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Collaborative Arrangements - Narrative (Details) course in Millions, $ in Millions | 1 Months Ended | 3 Months Ended | 6 Months Ended
--- | --- | --- | ---
Jan. 31, 2022 USD ($) | Mar. 31, 2021 USD ($) | Jun. 30, 2022 USD ($) course | Mar. 31, 2022 USD ($) | Jun. 30, 2021 USD ($) | Jun. 30, 2022 USD ($) market course | Jun. 30, 2021 USD ($)
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Amortization |  |  |  |  |  | $ 1,163 | $ 871
Number of markets (more than) | market |  |  |  |  |  | 40 |
Remaining minimum courses committed (in courses) | course |  |  | 1.1 |  |  | 1.1 |
Sales |  |  | $ 14,593 |  | $ 11,402 | $ 30,494 | 22,029
Operating Segments |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Sales |  |  | 14,223 |  | 11,452 | 29,812 | 22,108
Operating Segments | Pharmaceutical |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Sales |  |  | 12,756 |  | 9,980 | 26,863 | 19,218
Lynparza |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Amortization |  |  |  | $ 250 |  |  |
Lynparza | Other Noncurrent Assets |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Finite-lived intangible assets |  |  | 1,500 |  |  | 1,500 |
Lenvima | Operating Segments | Pharmaceutical |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Sales |  |  | 231 |  | 181 | 459 | 310
Lenvima | Other Noncurrent Assets |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Finite-lived intangible assets |  |  | 920 |  |  | 920 |
Verquvo | Other Intangible Assets |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Finite-lived intangible assets |  |  | 60 |  |  | 60 |
Adempas | Operating Segments | Pharmaceutical |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Sales |  |  | 63 |  | 74 | 124 | 129
Adempas | Other Intangible Assets |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Finite-lived intangible assets |  |  | 691 |  |  | 691 |
Alliance Revenue - Reblozyl | Operating Segments | Pharmaceutical |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Sales |  |  | 33 |  | $ 0 | 86 | $ 0
AstraZeneca | Sales-Based Milestones | Lynparza |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Probable contingent payments |  |  |  | 600 |  |  |
Liabilities |  |  |  | $ 600 |  |  |
Milestone payments accrued but not yet paid |  |  | 600 |  |  | 600 |
AstraZeneca | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Lynparza |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Sales-based milestone payments |  |  |  |  |  | 400 |
Potential future sales-based milestone payments |  |  | 2,100 |  |  | 2,100 |
Potential future regulatory milestone payments |  |  | 1,300 |  |  | 1,300 |
Capitalized milestone payment |  |  |  |  |  | 175 |
Eisai |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
License option payment related to collaborative arrangement |  | $ 125 |  |  |  |  |
Eisai | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Lenvima |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Sales-based milestone payments |  |  |  |  |  | 600 |
Potential future sales-based milestone payments |  |  | 2,600 |  |  | 2,600 |
Milestone payment accrued |  |  | $ 25 |  |  | 25 |
Capitalized milestone payment |  |  |  |  |  | $ 25 |
Bayer AG | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Sales-based milestone payments | $ 400 |  |  |  |  |  |
Bristol Myers Squibb | Licensing Agreements |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Royalty rate, deduction |  |  |  |  |  | 0.50 |
Royalties |  |  |  |  |  | $ 66 |
Bristol Myers Squibb | Licensing Agreements | Sales-Based Milestones |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Contingent milestone payments collaborative arrangement |  |  |  |  |  | 80 |
Bristol Myers Squibb | Licensing Agreements | Regulatory Milestones |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Contingent milestone payments collaborative arrangement |  |  |  |  |  | $ 20 |
Bristol Myers Squibb | Licensing Agreements | Minimum |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Royalty rate |  |  |  |  |  | 20.00% |
Bristol Myers Squibb | Licensing Agreements | Maximum |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Royalty rate |  |  |  |  |  | 24.00% |

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