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Collaborative Arrangements - Narrative (Details) course in Millions, $ in Millions | 1 Months Ended | 3 Months Ended | 9 Months Ended
--- | --- | --- | ---
Jan. 31, 2022 USD ($) | Mar. 31, 2021 USD ($) | Sep. 30, 2022 USD ($) course | Mar. 31, 2022 USD ($) | Sep. 30, 2021 USD ($) | Sep. 30, 2022 USD ($) market course | Sep. 30, 2021 USD ($)
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Amortization |  |  |  |  |  | $ 1,623 | $ 1,231
Number of markets (more than) | market |  |  |  |  |  | 40 |
Remaining minimum courses committed (in courses) | course |  |  | 0.8 |  |  | 0.8 |
Sales |  |  | $ 14,959 |  | $ 13,154 | $ 45,453 | 35,183
Operating Segments |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Sales |  |  | 14,334 |  | 12,913 | 44,146 | 35,021
Operating Segments | Pharmaceutical |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Sales |  |  | 12,963 |  | 11,496 | 39,826 | 30,714
Lynparza |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Amortization |  |  |  | $ 250 |  |  |
Lynparza | Other Noncurrent Assets |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Finite-lived intangible assets |  |  | 1,500 |  |  | 1,500 |
Lenvima | Operating Segments | Pharmaceutical |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Sales |  |  | 202 |  | 188 | 660 | 498
Lenvima | Other Noncurrent Assets |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Finite-lived intangible assets |  |  | 867 |  |  | 867 |
Verquvo | Other Intangible Assets |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Finite-lived intangible assets |  |  | 53 |  |  | 53 |
Adempas | Operating Segments | Pharmaceutical |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Sales |  |  | 57 |  | 59 | 181 | 188
Adempas | Other Intangible Assets |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Finite-lived intangible assets |  |  | 597 |  |  | 597 |
Alliance Revenue - Reblozyl | Operating Segments | Pharmaceutical |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Sales |  |  | 39 |  | $ 0 | 124 | $ 0
AstraZeneca | Sales-Based Milestones | Lynparza |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Probable contingent payments |  |  |  | 600 |  |  |
Liabilities |  |  |  | $ 600 |  |  |
Milestone payments accrued but not yet paid |  |  | 600 |  |  | 600 |
AstraZeneca | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Lynparza |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Sales-based milestone payments |  |  |  |  |  | 400 |
Potential future sales-based milestone payments |  |  | 2,100 |  |  | 2,100 |
Capitalized milestone payment |  |  |  |  |  | 250 |
Potential future regulatory milestone payments |  |  | 1,200 |  |  | 1,200 |
Eisai |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
License option payment related to collaborative arrangement |  | $ 125 |  |  |  |  |
Eisai | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Lenvima |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Sales-based milestone payments |  |  |  |  |  | 600 |
Potential future sales-based milestone payments |  |  | $ 2,600 |  |  | 2,600 |
Capitalized milestone payment |  |  |  |  |  | $ 50 |
Bayer AG | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Sales-based milestone payments | $ 400 |  |  |  |  |  |
Bristol Myers Squibb | Licensing Agreements |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Royalty rate, deduction |  |  |  |  |  | 0.50 |
Royalties |  |  |  |  |  | $ 104 |
Bristol Myers Squibb | Licensing Agreements | Sales-Based Milestones |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Contingent milestone payments collaborative arrangement |  |  |  |  |  | 80 |
Bristol Myers Squibb | Licensing Agreements | Regulatory Milestones |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Contingent milestone payments collaborative arrangement |  |  |  |  |  | $ 20 |
Bristol Myers Squibb | Licensing Agreements | Minimum |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Royalty rate |  |  |  |  |  | 20.00% |
Bristol Myers Squibb | Licensing Agreements | Maximum |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Royalty rate |  |  |  |  |  | 24.00% |

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