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Acquisitions, Research Collaborations and License Agreements (Details) $ in Millions | 1 Months Ended | 3 Months Ended | 9 Months Ended
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Oct. 31, 2022 USD ($) | Aug. 31, 2022 USD ($) | Jul. 31, 2022 USD ($) | May 31, 2022 USD ($) | Apr. 30, 2021 USD ($) | Jan. 31, 2021 USD ($) research_program collaboration_target | Dec. 31, 2022 USD ($) | Sep. 30, 2022 USD ($) | Sep. 30, 2021 USD ($) | Sep. 30, 2022 USD ($) | Sep. 30, 2021 USD ($)
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |
Upfront and milestone payments |  |  |  |  |  |  |  | $ 250.0 |  | $ 250.0 |
Research and development |  |  |  |  |  |  |  | $ 4,399.0 | $ 2,445.0 | $ 9,773.0 | $ 9,177.0
Subsequent Event |  |  |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |
Compensation earned | $ 50.0 |  |  |  |  |  |  |  |  |  |
Additional funding by others, percentage of development costs | 50.00% |  |  |  |  |  |  |  |  |  |
Additional funding by others, development costs subject to funding | $ 375.0 |  |  |  |  |  |  |  |  |  |
Pandion Therapeutics |  |  |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |
Research and development |  |  |  |  |  |  |  |  |  |  | 1,700.0
Consideration transferred, asset acquisition |  |  |  |  | $ 1,900.0 |  |  |  |  |  |
Asset acquisition costs |  |  |  |  | 147.0 |  |  |  |  |  |
Net assets |  |  |  |  | $ 156.0 |  |  |  |  |  |
Orna Therapeutics | Subsequent Event |  |  |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |
Amount paid for investment |  |  |  |  |  |  | $ 100.0 |  |  |  |
Orna Therapeutics | Licensing Agreements |  |  |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |
Upfront and milestone payments |  | $ 150.0 |  |  |  |  |  |  |  |  |
Orna Therapeutics | Licensing Agreements | Development Milestones |  |  |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |
Contingent milestone payments collaborative arrangement |  | 440.0 |  |  |  |  |  |  |  |  |
Orna Therapeutics | Licensing Agreements | Regulatory Milestones |  |  |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |
Contingent milestone payments collaborative arrangement |  | 675.0 |  |  |  |  |  |  |  |  |
Orna Therapeutics | Licensing Agreements | Sales-Based Milestones |  |  |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |
Contingent milestone payments collaborative arrangement |  | $ 2,400.0 |  |  |  |  |  |  |  |  |
Orion Corporation | Licensing Agreements |  |  |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |
Upfront and milestone payments |  |  | $ 290.0 |  |  |  |  |  |  |  |
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. | Licensing Agreements |  |  |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |
Upfront and milestone payments |  |  | 35.0 | $ 30.0 |  |  |  |  |  |  |
Milestone payments to be made to a collaborative partner |  |  |  | 30.0 |  |  |  |  |  |  |
Milestone payment to be made to a collaborative partner |  |  |  | 25.0 |  |  |  |  |  |  |
Research and development payments to be made to a collaborative partner (up to) |  |  |  | 101.0 |  |  |  |  |  |  |
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. | Licensing Agreements | Development Milestones |  |  |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |
Contingent milestone payments collaborative arrangement |  |  | 82.0 | 90.0 |  |  |  |  |  |  |
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. | Licensing Agreements | Regulatory Milestones |  |  |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |
Contingent milestone payments collaborative arrangement |  |  | 334.0 |  |  |  |  |  |  |  |
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. | Licensing Agreements | Sales-Based Milestones |  |  |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |
Contingent milestone payments collaborative arrangement |  |  | $ 485.0 | 780.0 |  |  |  |  |  |  |
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. | Licensing Agreements | First Commercial Sale Milestones |  |  |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |
Contingent milestone payments collaborative arrangement |  |  |  | $ 290.0 |  |  |  |  |  |  |
Artiva Biotherapeutics, Inc. | Licensing Agreements |  |  |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |
Upfront and milestone payments |  |  |  |  |  | $ 30.0 |  |  |  |  |
Upfront and milestone payments to be made |  |  |  |  |  | $ 15.0 |  |  |  |  |
Number of research programs | research_program |  |  |  |  |  | 3 |  |  |  |  |
Number of collaboration targets | collaboration_target |  |  |  |  |  | 3 |  |  |  |  |
Artiva Biotherapeutics, Inc. | Licensing Agreements | Minimum |  |  |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |
Royalty rate |  |  |  |  |  | 7.00% |  |  |  |  |
Artiva Biotherapeutics, Inc. | Licensing Agreements | Maximum |  |  |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |
Royalty rate |  |  |  |  |  | 14.00% |  |  |  |  |
Artiva Biotherapeutics, Inc. | Licensing Agreements | Development Milestones |  |  |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |
Contingent milestone payments collaborative arrangement |  |  |  |  |  | $ 217.5 |  |  |  |  |
Artiva Biotherapeutics, Inc. | Licensing Agreements | Regulatory Milestones |  |  |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |
Contingent milestone payments collaborative arrangement |  |  |  |  |  | 570.0 |  |  |  |  |
Artiva Biotherapeutics, Inc. | Licensing Agreements | Sales-Based Milestones |  |  |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |
Contingent milestone payments collaborative arrangement |  |  |  |  |  | $ 1,050.0 |  |  |  |  |
COVID-19 |  |  |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |
Charges related to program discontinuation |  |  |  |  |  |  |  |  |  |  | $ 207.0

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