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Collaborative Arrangements - Narrative (Details) - USD ($) $ in Millions | 3 Months Ended | 6 Months Ended | 12 Months Ended
--- | --- | --- | ---
Jun. 30, 2023 | Mar. 31, 2023 | Jun. 30, 2022 | Mar. 31, 2022 | Jun. 30, 2023 | Jun. 30, 2022 | Dec. 31, 2022
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Amortization |  |  |  |  | $ 1,020 | $ 1,163 |
Sales | $ 15,035 |  | $ 14,593 |  | 29,522 | 30,494 |
Operating Segments |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Sales | 14,913 |  | 14,223 |  | 29,126 | 29,812 |
Operating Segments | Pharmaceutical |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Sales | 13,457 |  | 12,756 |  | 26,179 | 26,863 |
Lynparza |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Amortization |  |  |  |  |  | 250 |
Lynparza | Other Noncurrent Assets |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Finite-lived intangible assets | 1,700 |  |  |  | 1,700 |  |
Lenvima |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Amortization |  |  |  |  | 72 |  |
Lenvima | Operating Segments | Pharmaceutical |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Sales | 242 |  | 231 |  | 474 | 459 |
Lenvima | Other Noncurrent Assets |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Finite-lived intangible assets | 756 |  |  |  | 756 |  |
Verquvo | Other Intangible Assets |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Finite-lived intangible assets | 55 |  |  |  | 55 |  |
Adempas | Operating Segments | Pharmaceutical |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Sales | 65 |  | 63 |  | 125 | 124 |
Adempas | Other Intangible Assets |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Finite-lived intangible assets | 586 |  |  |  | 586 |  |
Alliance Revenue - Reblozyl | Operating Segments | Pharmaceutical |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Sales | 47 |  | $ 33 |  | 90 | 86 |
AstraZeneca | Sales-Based Milestones | Lynparza |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Probable contingent payments |  |  |  | $ 600 |  |  |
Liabilities |  |  |  | $ 600 |  |  |
AstraZeneca | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Lynparza |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Sales-based milestone payments |  |  |  |  |  | 400 |
Potential future sales-based milestone payments | 2,100 |  |  |  | 2,100 |  |
Capitalized milestone payment | 245 | $ 105 |  |  |  | 175 | $ 250
Potential future regulatory milestone payments | 850 |  |  |  | 850 |  |
Eisai | Sales-Based Milestones | Lenvima |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Probable contingent payments |  | 125 |  |  |  |  |
Liabilities |  | $ 125 |  |  |  |  |
Eisai | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Lenvima |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Sales-based milestone payments |  |  |  |  |  | 600 |
Potential future sales-based milestone payments | $ 2,400 |  |  |  | $ 2,400 |  |
Capitalized milestone payment |  |  |  |  |  | 25 | $ 50
Bayer AG | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Sales-based milestone payments |  |  |  |  |  | 400 |
Bristol Myers Squibb Company | Licensing Agreements |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Royalty rate, deduction |  |  |  |  | 0.50 |  |
Bristol Myers Squibb Company | Licensing Agreements | Sales-Based Milestones |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Contingent proceeds collaborative arrangement |  |  |  |  | $ 80 |  |
Bristol Myers Squibb Company | Licensing Agreements | Regulatory Milestones |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Proceeds from collaborators |  |  |  |  |  | $ 20 |
Bristol Myers Squibb Company | Licensing Agreements | Minimum |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Royalty rate |  |  |  |  | 20.00% |  |
Bristol Myers Squibb Company | Licensing Agreements | Maximum |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Royalty rate |  |  |  |  | 24.00% |  |

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