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Acquisitions, Research Collaborations and License Agreements (Details) $ in Millions | 1 Months Ended | 3 Months Ended | 9 Months Ended | 17 Months Ended | 20 Months Ended |  |  |  |  |
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
Jun. 30, 2023 USD ($) | Feb. 28, 2023 USD ($) antibodyDrugConjugate | Jan. 31, 2023 USD ($) | Oct. 31, 2022 USD ($) | Sep. 30, 2023 USD ($) | Sep. 30, 2022 USD ($) | Sep. 30, 2023 USD ($) | Sep. 30, 2022 USD ($) | Sep. 30, 2023 USD ($) | Dec. 31, 2023 USD ($) | Oct. 31, 2023 USD ($) antibodyDrugConjugate | Dec. 31, 2022 USD ($) | Aug. 31, 2022 USD ($) | Jul. 31, 2022 USD ($) | May 31, 2022 USD ($)
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Research and development |  |  |  |  | $ 3,307 | $ 4,399 | $ 20,904 | $ 9,773 |  |  |  |  |  |  |
Royalty Pharma |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Compensation earned |  |  |  | $ 50 |  |  |  |  |  |  |  |  |  |  |
Additional funding by others, percentage of development costs |  |  |  | 50.00% |  |  |  |  |  |  |  |  |  |  |
Additional funding by others, development costs subject to funding |  |  |  | $ 375 |  |  |  |  |  |  |  |  |  |  |
Prometheus Biosciences, Inc. |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Consideration transferred, asset acquisition | $ 11,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Consideration transferred, to settle share-based equity awards | 1,200 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Consideration transferred, to settle equity awards, unvested | 700 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Net assets acquired | 877 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Cash recorded for asset acquisition | 368 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Investments recorded for asset acquisition | 296 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Deferred tax assets recorded for asset acquisition | 218 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Other net liabilities recorded for asset acquisition | $ 5 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Research and development |  |  |  |  |  |  | 10,200 |  |  |  |  |  |  |  |
Imago Bio Sciences, Inc. |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Consideration transferred, asset acquisition |  |  | $ 1,350 |  |  |  |  |  |  |  |  |  |  |  |
Net assets acquired |  |  | 219 |  |  |  |  |  |  |  |  |  |  |  |
Research and development |  |  |  |  |  |  | $ 1,200 |  |  |  |  |  |  |  |
Asset acquisition costs |  |  | 60 |  |  |  |  |  |  |  |  |  |  |  |
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Number of antibody drug conjugates obtained right and obligations | antibodyDrugConjugate |  | 7 |  |  |  |  |  |  |  |  |  |  |  |  |
Upfront and milestone payments made to collaborative partner |  | $ 175 |  |  |  | 35 |  | 35 |  |  |  |  |  |  |
Eligible future contingent development-related payments (up to) |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 90
Eligible future contingent regulatory milestone payments (up to) |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 334 |
Eligible future contingent sales-based milestone payments (up to) |  |  |  |  |  |  |  |  |  |  |  |  |  | 485 | 780
Stock investment in counterparty |  |  | $ 100 |  |  |  |  |  |  |  |  |  |  |  |
Option payment made to collaborative partner |  |  |  |  |  |  |  | 30 |  |  |  |  |  |  |
Milestone payment to be made to a collaborative partner |  |  |  |  | $ 25 |  |  |  |  |  |  |  |  |  |
Research and development payments made to a collaborative partner |  |  |  |  |  |  |  |  | $ 95 |  |  |  |  |  |
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Subsequent Event |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Number of antibody drug conjugates terminated with collaborative partner | antibodyDrugConjugate |  |  |  |  |  |  |  |  |  |  | 2 |  |  |  |
Eligible future contingent development-related payments (up to) |  |  |  |  |  |  |  |  |  |  | $ 725 |  |  |  |
Eligible future contingent regulatory milestone payments (up to) |  |  |  |  |  |  |  |  |  |  | 1,950 |  |  |  |
Eligible future contingent sales-based milestone payments (up to) |  |  |  |  |  |  |  |  |  |  | $ 3,900 |  |  |  |
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Development Milestones |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Eligible future contingent development-related payments (up to) |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 82 |
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | First Commercial Sale Milestones |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Eligible future contingent sales-based milestone payments (up to) |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 290
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Forecast |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Research and development payments to be made to a collaborative partner |  |  |  |  |  |  |  |  |  | $ 111 |  |  |  |  |
Moderna | Licensing Agreements |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Upfront and milestone payments made to collaborative partner |  |  |  |  |  | 250 |  | 250 |  |  |  |  |  |  |
Orna Therapeutics | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Eligible future contingent development-related payments (up to) |  |  |  |  |  |  |  |  |  |  |  |  | $ 440 |  |
Eligible future contingent regulatory milestone payments (up to) |  |  |  |  |  |  |  |  |  |  |  |  | 675 |  |
Eligible future contingent sales-based milestone payments (up to) |  |  |  |  |  |  |  |  |  |  |  |  | $ 2,400 |  |
Preferred stock investment in counterparty |  |  |  |  |  |  |  |  |  |  |  | $ 100 |  |  |
Orna Therapeutics | Licensing Agreements |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Upfront and milestone payments made to collaborative partner |  |  |  |  |  | 150 |  | 150 |  |  |  |  |  |  |
Orion Corporation | Licensing Agreements |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Upfront and milestone payments made to collaborative partner |  |  |  |  |  | $ 290 |  | $ 290 |  |  |  |  |  |  |

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