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Collaborative Arrangements - Narrative (Details) $ in Millions | 3 Months Ended | 9 Months Ended | 12 Months Ended |  |  |  |
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Dec. 31, 2023 USD ($) | Sep. 30, 2023 USD ($) | Jun. 30, 2023 USD ($) | Mar. 31, 2023 USD ($) | Sep. 30, 2022 USD ($) | Mar. 31, 2022 USD ($) | Sep. 30, 2023 USD ($) | Sep. 30, 2022 USD ($) | Dec. 31, 2022 USD ($) | Oct. 31, 2023 USD ($) antibodyDrugConjugate | Feb. 28, 2023 antibodyDrugConjugate | Jul. 31, 2022 USD ($) | May 31, 2022 USD ($)
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Amortization |  |  |  |  |  |  | $ 1,582 | $ 1,623 |  |  |  |  |
Sales |  | $ 15,962 |  |  | $ 14,959 |  | 45,485 | 45,453 |  |  |  |  |
Research and development expense |  | 3,307 |  |  | 4,399 |  | 20,904 | 9,773 |  |  |  |  |
Operating Segments |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Sales |  | 15,663 |  |  | 14,334 |  | 44,789 | 44,146 |  |  |  |  |
Operating Segments | Pharmaceutical |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Sales |  | 14,263 |  |  | 12,963 |  | 40,442 | 39,826 |  |  |  |  |
Lynparza |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Amortization |  |  |  |  |  |  |  | 250 |  |  |  |  |
Lynparza | Other Intangible Assets |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Finite-lived intangible assets |  | 1,600 |  |  |  |  | 1,600 |  |  |  |  |  |
Lenvima |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Amortization |  | 81 |  |  |  |  | 154 |  |  |  |  |  |
Lenvima | Operating Segments | Pharmaceutical |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Sales |  | 260 |  |  | 202 |  | 734 | 660 |  |  |  |  |
Lenvima | Other Intangible Assets |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Finite-lived intangible assets |  | 743 |  |  |  |  | 743 |  |  |  |  |  |
Verquvo | Other Intangible Assets |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Finite-lived intangible assets |  | 51 |  |  |  |  | 51 |  |  |  |  |  |
Adempas | Operating Segments | Pharmaceutical |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Sales |  | 65 |  |  | 57 |  | 189 | 181 |  |  |  |  |
Adempas | Other Intangible Assets |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Finite-lived intangible assets |  | 533 |  |  |  |  | 533 |  |  |  |  |  |
Alliance Revenue - Reblozyl | Operating Segments | Pharmaceutical |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Revenue from collaborative arrangement |  | 52 |  |  | $ 39 |  | 142 | 124 |  |  |  |  |
AstraZeneca | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Lynparza |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Probable contingent payments |  |  | $ 245 |  |  | $ 600 |  |  |  |  |  |  |
Liabilities |  |  |  |  |  | $ 600 |  |  |  |  |  |  |
Sales-based milestone payments |  |  |  |  |  |  |  | 400 |  |  |  |  |
Eligible future contingent sales-based milestone payments (up to) |  | 2,100 |  |  |  |  | 2,100 |  |  |  |  |  |
Capitalized milestone payment |  |  |  | $ 105 |  |  |  |  | $ 250 |  |  |  |
Eligible future contingent regulatory milestone payments (up to) |  | 850 |  |  |  |  | 850 |  |  |  |  |  |
Eisai | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Lenvima |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Probable contingent payments |  | 125 |  | $ 125 |  |  |  |  |  |  |  |  |
Liabilities |  | 250 |  |  |  |  | 250 |  |  |  |  |  |
Sales-based milestone payments |  |  |  |  |  |  |  | 600 |  |  |  |  |
Eligible future contingent sales-based milestone payments (up to) |  | $ 2,300 |  |  |  |  | $ 2,300 |  |  |  |  |  |
Capitalized milestone payment |  |  |  |  |  |  |  |  | $ 50 |  |  |  |
Bayer AG | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Sales-based milestone payments |  |  |  |  |  |  |  | 400 |  |  |  |  |
Bristol Myers Squibb Company | Licensing Agreements |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Royalty rate, deduction |  |  |  |  |  |  | 0.50 |  |  |  |  |  |
Bristol Myers Squibb Company | Licensing Agreements | Sales-Based Milestones |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Contingent proceeds collaborative arrangement |  |  |  |  |  |  | $ 80 |  |  |  |  |  |
Bristol Myers Squibb Company | Licensing Agreements | Regulatory Milestones |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Proceeds from collaborators |  |  |  |  |  |  |  | $ 20 |  |  |  |  |
Bristol Myers Squibb Company | Licensing Agreements | Minimum |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Royalty rate |  |  |  |  |  |  | 20.00% |  |  |  |  |  |
Bristol Myers Squibb Company | Licensing Agreements | Maximum |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Royalty rate |  |  |  |  |  |  | 24.00% |  |  |  |  |  |
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Eligible future contingent sales-based milestone payments (up to) |  |  |  |  |  |  |  |  |  |  |  | $ 485 | $ 780
Eligible future contingent regulatory milestone payments (up to) |  |  |  |  |  |  |  |  |  |  |  | $ 334 |
Number of antibody drug conjugates obtained right and obligations | antibodyDrugConjugate |  |  |  |  |  |  |  |  |  |  | 7 |  |
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Subsequent Event |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Eligible future contingent sales-based milestone payments (up to) |  |  |  |  |  |  |  |  |  | $ 3,900 |  |  |
Eligible future contingent regulatory milestone payments (up to) |  |  |  |  |  |  |  |  |  | $ 1,950 |  |  |
Daiichi Sankyo | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Subsequent Event |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Number of antibody drug conjugates obtained right and obligations | antibodyDrugConjugate |  |  |  |  |  |  |  |  |  | 3 |  |  |
Aggregate upfront payments due upon execution in collaborative arrangement |  |  |  |  |  |  |  |  |  | $ 4,000 |  |  |
Refundable upfront payments in collaborative arrangement |  |  |  |  |  |  |  |  |  | 1,000 |  |  |
Maximum aggregate contingent milestone payments, per product, in collaborative arrangement |  |  |  |  |  |  |  |  |  | 5,500 |  |  |
Daiichi Sankyo | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Subsequent Event | Forecast |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Research and development expense | $ 5,500 |  |  |  |  |  |  |  |  |  |  |  |
Daiichi Sankyo | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Ifinatamab Deruxtecan | Subsequent Event |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Refundable upfront payments in collaborative arrangement |  |  |  |  |  |  |  |  |  | 500 |  |  |
Daiichi Sankyo | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Patritumab Deruxtecan And Raludotatug Deruxtecan | Forecast |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Aggregate upfront payments due upon lapse of time in collaborative arrangement | $ 1,500 |  |  |  |  |  |  |  |  |  |  |  |
Daiichi Sankyo | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Patritumab Deruxtecan | Subsequent Event |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Refundable upfront payments in collaborative arrangement |  |  |  |  |  |  |  |  |  | 500 |  |  |
Aggregate upfront payments due upon lapse of time in collaborative arrangement |  |  |  |  |  |  |  |  |  | 750 |  |  |
Daiichi Sankyo | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Raludotatug Deruxtecan | Subsequent Event |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Aggregate upfront payments due upon lapse of time in collaborative arrangement |  |  |  |  |  |  |  |  |  | $ 750 |  |  |
Liable contracted portion of research and development expenses to incur costs for in collaborative arrangement, percentage |  |  |  |  |  |  |  |  |  | 75.00% |  |  |
Liable contracted portion of research and development expenses to incur costs for in collaborative arrangement |  |  |  |  |  |  |  |  |  | $ 2,000 |  |  |

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