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Acquisitions, Research Collaborations and License Agreements (Details)
$ in Millions
1 Months Ended 3 Months Ended 9 Months Ended 17 Months Ended 20 Months Ended
Jun. 30, 2023
USD ($)
Feb. 28, 2023
USD ($)
antibodyDrugConjugate
Jan. 31, 2023
USD ($)
Oct. 31, 2022
USD ($)
Sep. 30, 2023
USD ($)
Sep. 30, 2022
USD ($)
Sep. 30, 2023
USD ($)
Sep. 30, 2022
USD ($)
Sep. 30, 2023
USD ($)
Dec. 31, 2023
USD ($)
Oct. 31, 2023
USD ($)
antibodyDrugConjugate
Dec. 31, 2022
USD ($)
Aug. 31, 2022
USD ($)
Jul. 31, 2022
USD ($)
May 31, 2022
USD ($)
Business Acquisition [Line Items]                              
Research and development         $ 3,307 $ 4,399 $ 20,904 $ 9,773              
Royalty Pharma                              
Business Acquisition [Line Items]                              
Compensation earned       $ 50                      
Additional funding by others, percentage of development costs       50.00%                      
Additional funding by others, development costs subject to funding       $ 375                      
Prometheus Biosciences, Inc.                              
Business Acquisition [Line Items]                              
Consideration transferred, asset acquisition $ 11,000                            
Consideration transferred, to settle share-based equity awards 1,200                            
Consideration transferred, to settle equity awards, unvested 700                            
Net assets acquired 877                            
Cash recorded for asset acquisition 368                            
Investments recorded for asset acquisition 296                            
Deferred tax assets recorded for asset acquisition 218                            
Other net liabilities recorded for asset acquisition $ 5                            
Research and development             10,200                
Imago Bio Sciences, Inc.                              
Business Acquisition [Line Items]                              
Consideration transferred, asset acquisition     $ 1,350                        
Net assets acquired     219                        
Research and development             $ 1,200                
Asset acquisition costs     60                        
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement                              
Business Acquisition [Line Items]                              
Number of antibody drug conjugates obtained right and obligations | antibodyDrugConjugate   7                          
Upfront and milestone payments made to collaborative partner   $ 175       35   35              
Eligible future contingent development-related payments (up to)                             $ 90
Eligible future contingent regulatory milestone payments (up to)                           $ 334  
Eligible future contingent sales-based milestone payments (up to)                           485 780
Stock investment in counterparty     $ 100                        
Option payment made to collaborative partner               30              
Milestone payment to be made to a collaborative partner         $ 25                    
Research and development payments made to a collaborative partner                 $ 95            
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Subsequent Event                              
Business Acquisition [Line Items]                              
Number of antibody drug conjugates terminated with collaborative partner | antibodyDrugConjugate                     2        
Eligible future contingent development-related payments (up to)                     $ 725        
Eligible future contingent regulatory milestone payments (up to)                     1,950        
Eligible future contingent sales-based milestone payments (up to)                     $ 3,900        
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Development Milestones                              
Business Acquisition [Line Items]                              
Eligible future contingent development-related payments (up to)                           $ 82  
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | First Commercial Sale Milestones                              
Business Acquisition [Line Items]                              
Eligible future contingent sales-based milestone payments (up to)                             $ 290
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Forecast                              
Business Acquisition [Line Items]                              
Research and development payments to be made to a collaborative partner                   $ 111          
Moderna | Licensing Agreements                              
Business Acquisition [Line Items]                              
Upfront and milestone payments made to collaborative partner           250   250              
Orna Therapeutics | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement                              
Business Acquisition [Line Items]                              
Eligible future contingent development-related payments (up to)                         $ 440    
Eligible future contingent regulatory milestone payments (up to)                         675    
Eligible future contingent sales-based milestone payments (up to)                         $ 2,400    
Preferred stock investment in counterparty                       $ 100      
Orna Therapeutics | Licensing Agreements                              
Business Acquisition [Line Items]                              
Upfront and milestone payments made to collaborative partner           150   150              
Orion Corporation | Licensing Agreements                              
Business Acquisition [Line Items]                              
Upfront and milestone payments made to collaborative partner           $ 290   $ 290