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Segment Reporting - Reconciliation of Segment Profits to Income before Taxes (Details) - USD ($)
$ in Millions
3 Months Ended 9 Months Ended
Sep. 30, 2023
Sep. 30, 2022
Sep. 30, 2023
Sep. 30, 2022
Segment Reporting Information [Line Items]        
Profits $ 5,620 $ 3,583 $ 3,935 $ 12,931
Interest income 73 40 295 62
Interest expense (317) (244) (836) (727)
Amortization     (1,582) (1,623)
Depreciation     (1,326) (1,394)
Research and development (3,307) (4,399) (20,904) (9,773)
Restructuring costs (126) (94) (344) (288)
Operating Segments        
Segment Reporting Information [Line Items]        
Profits 10,828 10,105 30,853 29,935
Operating Segments | Pharmaceutical segment        
Segment Reporting Information [Line Items]        
Profits 10,407 9,590 29,400 28,263
Operating Segments | Animal Health segment        
Segment Reporting Information [Line Items]        
Profits 421 515 1,453 1,672
Corporate, Non-Segment        
Segment Reporting Information [Line Items]        
Profits 190 377 374 831
Segment Reconciling Items        
Segment Reporting Information [Line Items]        
Interest income 73 40 295 62
Interest expense (317) (244) (836) (727)
Amortization (562) (460) (1,582) (1,623)
Depreciation (401) (448) (1,175) (1,257)
Research and development (3,183) (4,277) (20,523) (9,374)
Restructuring costs (126) (94) (344) (288)
Charge for Zetia antitrust litigation settlements 0 0 (573) 0
Other unallocated, net $ (882) $ (1,416) $ (2,554) $ (4,628)