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Segment Reporting - Reconciliation of Segment Profits to Income Before Taxes (Details) - USD ($) $ in Millions | 12 Months Ended
--- | ---
Dec. 31, 2023 | Dec. 31, 2022 | Dec. 31, 2021
Segment Reporting Information [Line Items] |  |  |
Interest income | $ 365 | $ 157 | $ 36
Interest expense | (1,146) | (962) | (806)
Amortization | (2,044) | (2,085) | (1,636)
Depreciation | (1,828) | (1,824) | (1,578)
Research and development | (30,531) | (13,548) | (12,245)
Restructuring costs | (599) | (337) | (661)
Income before taxes | 1,889 | 16,444 | 13,879
Total segment profits |  |  |
Segment Reporting Information [Line Items] |  |  |
Depreciation | (203) | (182) | (164)
Income before taxes | 40,617 | 38,815 | 32,927
Total segment profits | Pharmaceutical segment |  |  |
Segment Reporting Information [Line Items] |  |  |
Depreciation | (5) | (5) | (6)
Income before taxes | 38,880 | 36,852 | 30,977
Total segment profits | Animal Health |  |  |
Segment Reporting Information [Line Items] |  |  |
Depreciation | (198) | (177) | (158)
Income before taxes | 1,737 | 1,963 | 1,950
Other profits |  |  |
Segment Reporting Information [Line Items] |  |  |
Income before taxes | 474 | 1,160 | 156
Unallocated |  |  |
Segment Reporting Information [Line Items] |  |  |
Interest income | 365 | 157 | 36
Interest expense | (1,146) | (962) | (806)
Amortization | (2,044) | (2,085) | (1,636)
Depreciation | (1,625) | (1,642) | (1,414)
Research and development | (30,008) | (13,011) | (11,692)
Charge for Zetia antitrust litigation settlements | (573) | 0 | 0
Other unallocated, net | $ (3,572) | $ (5,651) | $ (3,031)

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