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Segment Reporting - Reconciliation of Segment Profits to Income Before Taxes (Details) - USD ($)
$ in Millions
 12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Segment Reporting Information [Line Items]      
Interest income $ 365 $ 157 $ 36
Interest expense (1,146) (962) (806)
Amortization (2,044) (2,085) (1,636)
Depreciation (1,828) (1,824) (1,578)
Research and development (30,531) (13,548) (12,245)
Restructuring costs (599) (337) (661)
Income before taxes 1,889 16,444 13,879
Total segment profits      
Segment Reporting Information [Line Items]      
Depreciation (203) (182) (164)
Income before taxes 40,617 38,815 32,927
Total segment profits | Pharmaceutical segment      
Segment Reporting Information [Line Items]      
Depreciation (5) (5) (6)
Income before taxes 38,880 36,852 30,977
Total segment profits | Animal Health      
Segment Reporting Information [Line Items]      
Depreciation (198) (177) (158)
Income before taxes 1,737 1,963 1,950
Other profits      
Segment Reporting Information [Line Items]      
Income before taxes 474 1,160 156
Unallocated      
Segment Reporting Information [Line Items]      
Interest income 365 157 36
Interest expense (1,146) (962) (806)
Amortization (2,044) (2,085) (1,636)
Depreciation (1,625) (1,642) (1,414)
Research and development (30,008) (13,011) (11,692)
Charge for Zetia antitrust litigation settlements (573) 0 0
Other unallocated, net $ (3,572) $ (5,651) $ (3,031)