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Goodwill and Other Intangibles - Narrative (Details)
$ in Millions
 1 Months Ended 3 Months Ended 12 Months Ended
Dec. 31, 2022
USD ($)
Sep. 30, 2022
USD ($)
Dec. 31, 2023
USD ($)
Dec. 31, 2022
USD ($)
Dec. 31, 2021
USD ($)
Intangible Assets Excluding Goodwill [Line Items]          
Other intangibles, net $ 20,269   $ 18,011 $ 20,269  
Intangible asset impairment charges     $ 792 1,749 $ 302
Impairment, Intangible Asset, Indefinite-Lived (Excluding Goodwill), Statement of Income or Comprehensive Income [Extensible Enumeration]     Research and development    
Impairment, Intangible Asset, Finite-Lived, Statement of Income or Comprehensive Income [Extensible Enumeration]     Research and development    
Amortization expense for intangible assets     $ 2,000 2,100 1,600
Estimated aggregate amortization expense, 2024     1,800    
Estimated aggregate amortization expense, 2025     1,700    
Estimated aggregate amortization expense, 2026     1,600    
Estimated aggregate amortization expense, 2027     1,400    
Estimated aggregate amortization expense, 2028     1,100    
IPR&D          
Intangible Assets Excluding Goodwill [Line Items]          
IPR&D intangible asset 7,661   6,816 7,661  
Animal Health          
Intangible Assets Excluding Goodwill [Line Items]          
Other intangibles, net     4,200    
sotatercept | IPR&D          
Intangible Assets Excluding Goodwill [Line Items]          
IPR&D intangible asset     6,400    
gefapixant | IPR&D          
Intangible Assets Excluding Goodwill [Line Items]          
IPR&D impairment charges     779    
Lyfnua          
Intangible Assets Excluding Goodwill [Line Items]          
Finite-lived intangible assets, net     53    
nemtabrutinib | IPR&D          
Intangible Assets Excluding Goodwill [Line Items]          
IPR&D intangible asset     418    
IPR&D impairment charges 780 $ 807   1,600 $ 275
nemtabrutinib | Measurement Input, Discount Rate | Valuation Technique, Discounted Cash Flow          
Intangible Assets Excluding Goodwill [Line Items]          
Discount rate         0.085
Product rights          
Intangible Assets Excluding Goodwill [Line Items]          
Finite-lived intangible assets, net 6,810   5,878 6,810  
Product rights | Reblozyl          
Intangible Assets Excluding Goodwill [Line Items]          
Finite-lived intangible assets, net     3,200    
Product rights | Zerbaxa          
Intangible Assets Excluding Goodwill [Line Items]          
Finite-lived intangible assets, net     333    
Product rights | Sivextro          
Intangible Assets Excluding Goodwill [Line Items]          
Finite-lived intangible assets, net     106    
Product rights | Animal Health          
Intangible Assets Excluding Goodwill [Line Items]          
Finite-lived intangible assets, net     2,000    
Trade names          
Intangible Assets Excluding Goodwill [Line Items]          
Finite-lived intangible assets, net 2,244   2,105 2,244  
Trade names | Animal Health          
Intangible Assets Excluding Goodwill [Line Items]          
Finite-lived intangible assets, net     2,100    
Licenses and other          
Intangible Assets Excluding Goodwill [Line Items]          
Finite-lived intangible assets, net $ 3,554   3,212 3,554  
Licenses and other | Lynparza | Licenses and other          
Intangible Assets Excluding Goodwill [Line Items]          
Finite-lived intangible assets, net     1,500    
Licenses and other | Lenvima | Licenses and other          
Intangible Assets Excluding Goodwill [Line Items]          
Finite-lived intangible assets, net     683    
Licenses and other | Adempas | Licenses and other          
Intangible Assets Excluding Goodwill [Line Items]          
Finite-lived intangible assets, net     $ 526    
Licenses and other | derazantinib          
Intangible Assets Excluding Goodwill [Line Items]          
Intangible asset impairment charge related to finite-lived intangible asset       $ 80