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Segment Reporting - Reconciliation of Segment Profits to Income before Taxes (Details) - USD ($) $ in Millions	3 Months Ended		6 Months Ended
	Jun. 30, 2024	Jun. 30, 2023	Jun. 30, 2024	Jun. 30, 2023
Segment Reporting Information [Line Items]
Profits	$ 6,006	$ (5,335)	$ 11,675	$ (1,685)
Interest income	69	109	141	221
Interest expense	(310)	(277)	(613)	(519)
Amortization			(1,087)	(1,020)
Depreciation			(1,029)	(874)
Research and development	(3,500)	(13,321)	(7,492)	(17,597)
Restructuring costs	(80)	(151)	(202)	(218)
Operating Segments
Segment Reporting Information [Line Items]
Profits	11,708	10,321	23,168	20,025
Operating Segments | Pharmaceutical segment
Segment Reporting Information [Line Items]
Profits	11,200	9,854	22,104	18,993
Operating Segments | Animal Health segment
Segment Reporting Information [Line Items]
Profits	508	467	1,064	1,032
Corporate, Non-Segment
Segment Reporting Information [Line Items]
Profits	129	19	274	184
Interest income	69	109	141	221
Interest expense	(310)	(277)	(613)	(519)
Amortization	(614)	(477)	(1,087)	(1,020)
Depreciation	(450)	(376)	(902)	(775)
Research and development	(3,360)	(13,194)	(7,209)	(17,341)
Restructuring costs	(80)	(151)	(202)	(218)
Charge for Zetia antitrust litigation settlements	0	0	0	(573)
Other unallocated, net	$ (1,086)	$ (1,309)	$ (1,895)	$ (1,669)

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