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Acquisitions, Divestitures, Research Collaborations and Licensing Agreements - Narrative (Details) $ in Millions |  | 1 Months Ended | 3 Months Ended | 9 Months Ended |  |  |
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Jun. 02, 2021 | Sep. 30, 2024 USD ($) jurisdiction | Jul. 31, 2024 USD ($) candidate aqua_facility | Mar. 31, 2024 USD ($) | Jun. 30, 2023 USD ($) | Jan. 31, 2023 USD ($) | Sep. 30, 2024 USD ($) jurisdiction | Dec. 31, 2023 USD ($) | Sep. 30, 2023 USD ($) | Sep. 30, 2024 USD ($) jurisdiction | Sep. 30, 2023 USD ($) | Apr. 30, 2024 candidate | Oct. 31, 2023 USD ($) candidate | Feb. 28, 2023 candidate
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Research and development |  |  |  |  |  |  | $ 5,862 |  | $ 3,307 | $ 13,354 | $ 20,904 |  |  |
Sales |  |  |  |  |  |  | 16,657 |  | 15,962 | 48,544 | 45,485 |  |  |
Cost of sales |  |  |  |  |  |  | 4,080 |  | 4,264 | 11,365 | 12,214 |  |  |
Other current assets |  | $ 8,143 |  |  |  |  | 8,143 | $ 8,368 |  | 8,143 |  |  |  |
Accrued and other current liabilities |  | 16,539 |  |  |  |  | 16,539 | 15,766 |  | 16,539 |  |  |  |
Related Party |  |  |  |  |  |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Other current assets |  | 370 |  |  |  |  | 370 | 632 |  | 370 |  |  |  |
Accrued and other current liabilities |  | $ 130 |  |  |  |  | 130 | 598 |  | 130 |  |  |  |
Manufacturing and Supply Agreements | Related Party |  |  |  |  |  |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Sales |  |  |  |  |  |  | 109 |  | 100 | 309 | 290 |  |  |
Cost of sales |  |  |  |  |  |  | $ 108 |  | 106 | $ 310 | 314 |  |  |
Minimum | Manufacturing and Supply Agreements | Related Party |  |  |  |  |  |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Period of continuing involvement after disposal | 4 years |  |  |  |  |  |  |  |  |  |  |  |  |
Maximum | Manufacturing and Supply Agreements | Related Party |  |  |  |  |  |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Period of continuing involvement after disposal | 10 years |  |  |  |  |  |  |  |  |  |  |  |  |
Discontinued Operations, Disposed of by Means Other than Sale, Spinoff | Organon & Co. |  |  |  |  |  |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Number of jurisdictions remaining | jurisdiction |  | 1 |  |  |  |  | 1 |  |  | 1 |  |  |  |
Orion |  |  |  |  |  |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Eligible future contingent development-related payments (up to) |  |  | $ 30 |  |  |  |  |  |  |  |  |  |  |
Eligible future contingent regulatory milestone payments (up to) |  |  | 625 |  |  |  |  |  |  |  |  |  |  |
Eligible future contingent sales-based milestone payments (up to) |  |  | $ 975 |  |  |  |  |  |  |  |  |  |  |
Daiichi Sankyo | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement |  |  |  |  |  |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Research and development |  |  |  |  |  |  | $ 94 | 5,500 | 0 | $ 227 | 0 |  |  |
Number of antibody drug conjugates obtained right and obligations | candidate |  |  |  |  |  |  |  |  |  |  |  |  | 3 |
Accrued and other current liabilities |  | $ 811 |  |  |  |  | 811 | $ 800 |  | 811 |  |  |  |
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement |  |  |  |  |  |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Eligible future contingent development-related payments (up to) |  |  |  |  |  |  |  |  |  |  |  |  | $ 540 |
Eligible future contingent regulatory milestone payments (up to) |  |  |  |  |  |  |  |  |  |  |  |  | 1,500 |
Eligible future contingent sales-based milestone payments (up to) |  |  |  |  |  |  |  |  |  |  |  |  | $ 3,100 |
Number of antibody drug conjugates | candidate |  |  |  |  |  |  |  |  |  |  |  |  |  | 7
Upfront payment made to collaborative partner |  |  |  |  |  |  |  |  | $ 175 |  | 175 |  |  |
Number of antibody drug conjugates terminated | candidate |  |  |  |  |  |  |  |  |  |  |  | 1 | 2 |
Number of exercised license option antibody drug conjugates | candidate |  |  | 1 |  |  |  |  |  |  |  |  |  |  |
Number of licensed antibody drug conjugates | candidate |  |  | 3 |  |  |  |  |  |  |  |  |  |  |
Number of unexercised license option antibody drug conjugates | candidate |  |  | 1 |  |  |  |  |  |  |  |  |  |  |
Payment resulting from the license option exercise |  |  | $ 38 |  |  |  |  |  |  |  |  |  |  |
Stock investment in counterparty |  |  |  |  |  | $ 100 |  |  |  |  |  |  |  |
Elanco Animal Health Incorporated Aqua Business |  |  |  |  |  |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Payment to acquire business |  |  | $ 1,300 |  |  |  |  |  |  |  |  |  |  |
Aqua manufacturing facilities | aqua_facility |  |  | 2 |  |  |  |  |  |  |  |  |  |  |
CN201, Curon Biopharmaceutical |  |  |  |  |  |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Consideration transferred, asset acquisition |  | 700 |  |  |  |  |  |  |  |  |  |  |  |
Future contingent developmental milestone payments (up to) |  | 300 |  |  |  |  | 300 |  |  | 300 |  |  |  |
Future regulatory milestone payments (up to) |  | 300 |  |  |  |  | 300 |  |  | 300 |  |  |  |
Research and development |  |  |  |  |  |  | 750 |  |  | 750 |  |  |  |
CN201, Curon Biopharmaceutical | Third-Party |  |  |  |  |  |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Aggregate contingent developmental, regulatory, and sales-based-related payments |  | $ 128 |  |  |  |  | 128 |  |  | 128 |  |  |  |
Eyebiotech Limited |  |  |  |  |  |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Consideration transferred, asset acquisition |  |  | $ 1,200 |  |  |  |  |  |  |  |  |  |  |
Future contingent developmental milestone payments (up to) |  |  | 200 |  |  |  |  |  |  |  |  |  |  |
Future regulatory milestone payments (up to) |  |  | 1,000 |  |  |  |  |  |  |  |  |  |  |
Research and development |  |  |  |  |  |  | 1,350 |  |  | 1,350 |  |  |  |
Asset acquisition, transaction costs |  |  | 207 |  |  |  |  |  |  |  |  |  |  |
Developmental milestone payment triggered |  |  |  |  |  |  | 100 |  |  |  |  |  |  |
Maximum aggregate sales-based milestone payments |  |  | $ 500 |  |  |  |  |  |  |  |  |  |  |
Net assets acquired |  |  |  |  |  |  | $ 21 |  |  | 21 |  |  |  |
Harpoon Therapeutics, Inc. |  |  |  |  |  |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Consideration transferred, asset acquisition |  |  |  | $ 765 |  |  |  |  |  |  |  |  |  |
Research and development |  |  |  |  |  |  |  |  |  | 656 |  |  |  |
Asset acquisition, transaction costs |  |  |  | $ 56 |  |  |  |  |  |  |  |  |  |
Net assets acquired |  |  |  |  |  |  |  |  |  | $ 165 |  |  |  |
Prometheus Biosciences, Inc. |  |  |  |  |  |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Consideration transferred, asset acquisition |  |  |  |  | $ 11,000 |  |  |  |  |  |  |  |  |
Research and development |  |  |  |  |  |  |  |  |  |  | 10,200 |  |  |
Net assets acquired |  |  |  |  | 877 |  |  |  |  |  |  |  |  |
Consideration transferred, to settle share-based equity awards |  |  |  |  | 1,200 |  |  |  |  |  |  |  |  |
Consideration transferred, to settle equity awards, unvested |  |  |  |  | 700 |  |  |  |  |  |  |  |  |
Cash recorded for asset acquisition |  |  |  |  | 368 |  |  |  |  |  |  |  |  |
Investments recorded for asset acquisition |  |  |  |  | 296 |  |  |  |  |  |  |  |  |
Deferred tax assets recorded for asset acquisition |  |  |  |  | 218 |  |  |  |  |  |  |  |  |
Other net liabilities recorded for asset acquisition |  |  |  |  | $ 5 |  |  |  |  |  |  |  |  |
Imago Bio Sciences, Inc. |  |  |  |  |  |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Consideration transferred, asset acquisition |  |  |  |  |  | 1,350 |  |  |  |  |  |  |  |
Research and development |  |  |  |  |  |  |  |  |  |  | $ 1,200 |  |  |
Asset acquisition, transaction costs |  |  |  |  |  | 60 |  |  |  |  |  |  |  |
Net assets acquired |  |  |  |  |  | $ 219 |  |  |  |  |  |  |  |

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