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Collaborative Arrangements - Daiicho Sankyo - Narrative (Details)
$ in Millions
1 Months Ended 3 Months Ended 9 Months Ended
Aug. 31, 2024
USD ($)
Sep. 30, 2024
USD ($)
Dec. 31, 2023
USD ($)
Sep. 30, 2023
USD ($)
Sep. 30, 2024
USD ($)
Sep. 30, 2023
USD ($)
Oct. 31, 2023
USD ($)
candidate
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]              
Research and development   $ 5,862   $ 3,307 $ 13,354 $ 20,904  
Daiichi Sankyo | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement              
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]              
Number of antibody drug conjugates obtained right and obligations | candidate             3
Aggregate upfront payments due upon execution in collaborative arrangement             $ 4,000
Refundable upfront payments in collaborative arrangement             1,000
Maximum aggregate contingent milestone payments, per product, in collaborative arrangement             $ 5,500
Research and development   $ 94 $ 5,500 $ 0 $ 227 $ 0  
Sales based royalty percentage             5.00%
Upfront cash payment $ 170            
Daiichi Sankyo | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Ifinatamab Deruxtecan              
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]              
Refundable upfront payments in collaborative arrangement             $ 500
Daiichi Sankyo | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Patritumab Deruxtecan              
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]              
Refundable upfront payments in collaborative arrangement             500
Aggregate upfront payments due upon lapse of time in collaborative arrangement             750
Daiichi Sankyo | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Raludotatug Deruxtecan              
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]              
Aggregate upfront payments due upon lapse of time in collaborative arrangement             $ 750
Liable contracted portion of research and development expenses to incur costs for in collaborative arrangement, percentage             75.00%
Liable contracted portion of research and development expenses to incur costs for in collaborative arrangement             $ 2,000
Daiichi Sankyo | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Patritumab Deruxtecan And Raludotatug Deruxtecan              
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]              
Aggregate upfront payments due upon lapse of time in collaborative arrangement     $ 1,500