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Collaborative Arrangements - Daiicho Sankyo (Details) - USD ($)
$ in Millions
3 Months Ended 9 Months Ended
Sep. 30, 2024
Dec. 31, 2023
Sep. 30, 2023
Sep. 30, 2024
Sep. 30, 2023
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Selling, general and administrative $ 2,731   $ 2,519 $ 7,952 $ 7,700
Research and development 5,862   3,307 13,354 20,904
Accrued and other current liabilities 16,539 $ 15,766   16,539  
Daiichi Sankyo | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Selling, general and administrative 5   0 21 0
Research and development 94 5,500 $ 0 227 $ 0
Accrued and other current liabilities 811 800   811  
Other noncurrent liabilities $ 750 $ 750   $ 750