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Collaborative Arrangements - AstraZeneca PLC - Narrative (Details) - USD ($) $ in Millions | 12 Months Ended
--- | ---
Dec. 31, 2024 | Dec. 31, 2023 | Dec. 31, 2022
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |
Amortization expense for intangible assets | $ 2,400 | $ 2,000 | $ 2,100
Licenses and other |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |
Intangible assets | 3,091 | 3,212 |
Koselugo | Licenses and other |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |
Intangible assets | 49 |  |
Lynparza | Licenses and other |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |
Intangible assets | 1,200 |  |
AstraZeneca |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |
Amortization expense for intangible assets | 48 |  | 250
AstraZeneca | Koselugo | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |
Probable contingent payments | 100 |  |
Liabilities | 100 |  |
AstraZeneca | Lynparza | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |
Milestone payments sales-based |  |  | 400
Probable contingent payments |  |  | 600
Liabilities |  |  | 600
Sales milestone payments | 2,000 |  |
Regulatory milestone payments | $ 245 | $ 105 | $ 250

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