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Goodwill and Other Intangibles - Narrative (Details) - USD ($) $ in Millions | 1 Months Ended | 3 Months Ended | 12 Months Ended
--- | --- | --- | ---
Dec. 31, 2022 | Sep. 30, 2022 | Dec. 31, 2024 | Dec. 31, 2023 | Dec. 31, 2022
Intangible Assets Excluding Goodwill [Line Items] |  |  |  |  |
Other intangibles, net |  |  | $ 16,370 | $ 18,011 |
Intangible asset impairment charges |  |  | 39 | $ 792 | $ 1,749
Impairment, Intangible Asset, Indefinite-Lived (Excluding Goodwill), Statement of Income or Comprehensive Income [Extensible Enumeration] |  |  |  | Research and development | Research and development
Impairment, Intangible Asset, Finite-Lived, Statement of Income or Comprehensive Income [Extensible Enumeration] |  |  |  |  | Research and development
Amortization expense for intangible assets |  |  | 2,400 | $ 2,000 | $ 2,100
Estimated aggregate amortization expense, 2025 |  |  | 2,400 |  |
Estimated aggregate amortization expense, 2026 |  |  | 2,300 |  |
Estimated aggregate amortization expense, 2027 |  |  | 2,100 |  |
Estimated aggregate amortization expense, 2028 |  |  | 1,800 |  |
Estimated aggregate amortization expense, 2029 |  |  | 1,500 |  |
IPR&D |  |  |  |  |
Intangible Assets Excluding Goodwill [Line Items] |  |  |  |  |
IPR&D intangible asset |  |  | 430 | 6,816 |
Animal Health |  |  |  |  |
Intangible Assets Excluding Goodwill [Line Items] |  |  |  |  |
Other intangibles, net |  |  | 4,300 |  |
gefapixant | IPR&D |  |  |  |  |
Intangible Assets Excluding Goodwill [Line Items] |  |  |  |  |
IPR&D impairment charges |  |  |  | 779 |
Lyfnua |  |  |  |  |
Intangible Assets Excluding Goodwill [Line Items] |  |  |  |  |
Finite-lived intangible assets, net |  |  | 21 |  |
nemtabrutinib | IPR&D |  |  |  |  |
Intangible Assets Excluding Goodwill [Line Items] |  |  |  |  |
IPR&D intangible asset |  |  | 418 |  |
IPR&D impairment charges | $ 780 | $ 807 |  |  | 1,600
Product rights |  |  |  |  |
Intangible Assets Excluding Goodwill [Line Items] |  |  |  |  |
Finite-lived intangible assets, net |  |  | 10,922 | 5,878 |
Product rights | Reblozyl |  |  |  |  |
Intangible Assets Excluding Goodwill [Line Items] |  |  |  |  |
Finite-lived intangible assets, net |  |  | 2,800 |  |
Product rights | Zerbaxa |  |  |  |  |
Intangible Assets Excluding Goodwill [Line Items] |  |  |  |  |
Finite-lived intangible assets, net |  |  | 260 |  |
Product rights | Animal Health |  |  |  |  |
Intangible Assets Excluding Goodwill [Line Items] |  |  |  |  |
Finite-lived intangible assets, net |  |  | 1,700 |  |
Product rights | Winrevair |  |  |  |  |
Intangible Assets Excluding Goodwill [Line Items] |  |  |  |  |
Finite-lived intangible assets, net |  |  | 5,900 |  |
Trade names |  |  |  |  |
Intangible Assets Excluding Goodwill [Line Items] |  |  |  |  |
Finite-lived intangible assets, net |  |  | 1,927 | 2,105 |
Trade names | Animal Health |  |  |  |  |
Intangible Assets Excluding Goodwill [Line Items] |  |  |  |  |
Finite-lived intangible assets, net |  |  | 1,900 |  |
Licenses and other |  |  |  |  |
Intangible Assets Excluding Goodwill [Line Items] |  |  |  |  |
Finite-lived intangible assets, net |  |  | 3,091 | $ 3,212 |
Licenses and other | Lynparza |  |  |  |  |
Intangible Assets Excluding Goodwill [Line Items] |  |  |  |  |
Finite-lived intangible assets, net |  |  | 1,200 |  |
Licenses and other | Lenvima |  |  |  |  |
Intangible Assets Excluding Goodwill [Line Items] |  |  |  |  |
Finite-lived intangible assets, net |  |  | 442 |  |
Licenses and other | Adempas |  |  |  |  |
Intangible Assets Excluding Goodwill [Line Items] |  |  |  |  |
Finite-lived intangible assets, net |  |  | $ 372 |  |
Licenses and other | derazantinib |  |  |  |  |
Intangible Assets Excluding Goodwill [Line Items] |  |  |  |  |
Intangible asset impairment charge related to finite-lived intangible asset |  |  |  |  | $ 80

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