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Collaborative Arrangements - AstraZeneca PLC (Details) - USD ($) $ in Millions	3 Months Ended
	Mar. 31, 2025	Mar. 31, 2024	Dec. 31, 2024
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Cost of sales	$ 3,419	$ 3,540
Selling, general and administrative	2,552	2,483
Research and development	3,621	3,992
Other current assets	35,503		$ 38,782
Accrued and other current liabilities	12,772		15,694
AstraZeneca | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Revenue from collaborative arrangement	356	330
Cost of sales	83	82
Selling, general and administrative	32	39
Research and development	12	20
Other current assets	358		424
Accrued and other current liabilities	15		$ 713
AstraZeneca | Alliance revenue - Lynparza | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Revenue from collaborative arrangement	312	292
AstraZeneca | Alliance revenue - Koselugo | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Revenue from collaborative arrangement	$ 44	$ 38

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