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Collaborative Arrangements - Daiicho Sankyo - Narrative (Details)
$ in Millions
1 Months Ended 3 Months Ended 12 Months Ended
Aug. 31, 2024
USD ($)
Mar. 31, 2025
USD ($)
Mar. 31, 2024
USD ($)
Dec. 31, 2023
USD ($)
Oct. 31, 2023
USD ($)
candidate
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Research and development   $ 3,621 $ 3,992    
Daiichi Sankyo | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Number of antibody drug conjugates obtained right and obligations | candidate         3
Aggregate upfront payments due upon execution in collaborative arrangement         $ 4,000
Refundable upfront payments in collaborative arrangement         1,000
Maximum aggregate contingent milestone payments, per product, in collaborative arrangement         $ 5,500
Research and development   $ 128 $ 69 $ 5,500  
Sales based royalty percentage         5.00%
Upfront cash payment $ 170        
Daiichi Sankyo | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Ifinatamab Deruxtecan          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Refundable upfront payments in collaborative arrangement         $ 500
Daiichi Sankyo | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Patritumab Deruxtecan          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Refundable upfront payments in collaborative arrangement         500
Aggregate upfront payments due upon lapse of time in collaborative arrangement         750
Daiichi Sankyo | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Raludotatug Deruxtecan          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Aggregate upfront payments due upon lapse of time in collaborative arrangement         $ 750
Liable contracted portion of research and development expenses to incur costs for in collaborative arrangement, percentage         75.00%
Liable contracted portion of research and development expenses to incur costs for in collaborative arrangement         $ 2,000
Daiichi Sankyo | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Patritumab Deruxtecan and Ralduotatug Deruxtecan          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Aggregate upfront payments due upon lapse of time in collaborative arrangement       $ 1,500