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Segment Reporting | 6 Months Ended
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Jun. 30, 2025
Segment Reporting [Abstract] |
Segment Reporting | Segment Reporting The Company’s operations are principally managed on a product basis and include two operating segments, Pharmaceutical and Animal Health, both of which are reportable segments. The Pharmaceutical segment includes human health pharmaceutical and vaccine products. Human health pharmaceutical products consist of therapeutic and preventive agents, generally sold by prescription, for the treatment of human disorders. The Company sells these human health pharmaceutical products primarily to drug wholesalers and retailers, hospitals, government agencies and managed health care providers such as health maintenance organizations, pharmacy benefit managers and other institutions. Human health vaccine products consist of preventive pediatric, adolescent and adult vaccines. The Company sells these human health vaccines primarily to physicians, wholesalers, distributors and government entities. A large component of pediatric and adolescent vaccine sales are made to the U.S. Centers for Disease Control and Prevention Vaccines for Children program, which is funded by the U.S. government. Additionally, the Company sells vaccines to the Federal government for placement into vaccine stockpiles. The Animal Health segment discovers, develops, manufactures and markets a wide range of veterinary pharmaceutical and vaccine products, as well as health management solutions and services, for the prevention, treatment and control of disease in all major livestock and companion animal species. The Company also offers an extensive suite of digitally connected identification, traceability and monitoring products. The Company sells its products to veterinarians, distributors, animal producers, farmers and pet owners. Sales of the Company’s products were as follows:
| Three Months Ended June 30, |  | Six Months Ended June 30,
| 2025 |  | 2024 |  | 2025 |  | 2024
($ in millions) | U.S. |  | Int’l |  | Total |  | U.S. |  | Int’l |  | Total |  | U.S. |  | Int’l |  | Total |  | U.S. |  | Int’l |  | Total
Pharmaceutical: |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Oncology |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Keytruda | $ | 4,749 |  |  | $ | 3,207 |  |  | $ | 7,956 |  |  | $ | 4,412 |  |  | $ | 2,858 |  |  | $ | 7,270 |  |  | $ | 9,057 |  |  | $ | 6,104 |  |  | $ | 15,161 |  |  | $ | 8,531 |  |  | $ | 5,686 |  |  | $ | 14,217 |
Alliance revenue-Lynparza (1) | 174 |  |  | 195 |  |  | 370 |  |  | 153 |  |  | 165 |  |  | 317 |  |  | 319 |  |  | 363 |  |  | 682 |  |  | 288 |  |  | 321 |  |  | 609 |
Alliance revenue-Lenvima (1) | 183 |  |  | 83 |  |  | 265 |  |  | 177 |  |  | 73 |  |  | 249 |  |  | 368 |  |  | 155 |  |  | 523 |  |  | 349 |  |  | 155 |  |  | 504 |
Welireg | 138 |  |  | 24 |  |  | 162 |  |  | 116 |  |  | 10 |  |  | 126 |  |  | 261 |  |  | 39 |  |  | 300 |  |  | 194 |  |  | 17 |  |  | 211 |
Alliance revenue-Reblozyl (2) | 88 |  |  | 19 |  |  | 107 |  |  | 75 |  |  | 15 |  |  | 90 |  |  | 189 |  |  | 37 |  |  | 226 |  |  | 133 |  |  | 28 |  |  | 161 |
Vaccines |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Gardasil/Gardasil 9 | 545 |  |  | 581 |  |  | 1,126 |  |  | 536 |  |  | 1,941 |  |  | 2,478 |  |  | 1,082 |  |  | 1,371 |  |  | 2,453 |  |  | 1,024 |  |  | 3,702 |  |  | 4,727 |
ProQuad/M-M-R II/Varivax | 481 |  |  | 128 |  |  | 609 |  |  | 490 |  |  | 127 |  |  | 617 |  |  | 903 |  |  | 245 |  |  | 1,148 |  |  | 928 |  |  | 259 |  |  | 1,187 |
Vaxneuvance | 136 |  |  | 93 |  |  | 229 |  |  | 99 |  |  | 90 |  |  | 189 |  |  | 275 |  |  | 184 |  |  | 459 |  |  | 260 |  |  | 148 |  |  | 408 |
RotaTeq | 60 |  |  | 61 |  |  | 121 |  |  | 107 |  |  | 56 |  |  | 163 |  |  | 225 |  |  | 125 |  |  | 349 |  |  | 257 |  |  | 123 |  |  | 379 |
Capvaxive | 129 |  |  | — |  |  | 129 |  |  | — |  |  | — |  |  | — |  |  | 235 |  |  | 1 |  |  | 236 |  |  | — |  |  | — |  |  | — |
Pneumovax 23 | 5 |  |  | 33 |  |  | 38 |  |  | 11 |  |  | 48 |  |  | 59 |  |  | 3 |  |  | 76 |  |  | 79 |  |  | 17 |  |  | 103 |  |  | 120 |
Hospital Acute Care |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Bridion | 411 |  |  | 50 |  |  | 461 |  |  | 351 |  |  | 104 |  |  | 455 |  |  | 789 |  |  | 113 |  |  | 902 |  |  | 680 |  |  | 215 |  |  | 895 |
Prevymis | 115 |  |  | 113 |  |  | 228 |  |  | 90 |  |  | 98 |  |  | 188 |  |  | 217 |  |  | 219 |  |  | 436 |  |  | 165 |  |  | 197 |  |  | 362 |
Dificid | 83 |  |  | 13 |  |  | 96 |  |  | 79 |  |  | 12 |  |  | 92 |  |  | 155 |  |  | 24 |  |  | 179 |  |  | 147 |  |  | 17 |  |  | 165 |
Zerbaxa | 45 |  |  | 29 |  |  | 74 |  |  | 33 |  |  | 28 |  |  | 62 |  |  | 87 |  |  | 57 |  |  | 145 |  |  | 67 |  |  | 51 |  |  | 118 |
Cardiovascular |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Winrevair | 323 |  |  | 12 |  |  | 336 |  |  | 70 |  |  | — |  |  | 70 |  |  | 591 |  |  | 24 |  |  | 615 |  |  | 70 |  |  | — |  |  | 70 |
Alliance revenue-Adempas/Verquvo (3) | 108 |  |  | 15 |  |  | 123 |  |  | 98 |  |  | 8 |  |  | 106 |  |  | 205 |  |  | 23 |  |  | 229 |  |  | 188 |  |  | 16 |  |  | 203 |
Adempas | — |  |  | 80 |  |  | 80 |  |  | — |  |  | 72 |  |  | 72 |  |  | — |  |  | 147 |  |  | 147 |  |  | — |  |  | 142 |  |  | 142 |
Virology |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Lagevrio | 30 |  |  | 52 |  |  | 83 |  |  | 15 |  |  | 95 |  |  | 110 |  |  | 66 |  |  | 119 |  |  | 185 |  |  | 60 |  |  | 400 |  |  | 460 |
Isentress/Isentress HD | 48 |  |  | 38 |  |  | 86 |  |  | 43 |  |  | 46 |  |  | 89 |  |  | 99 |  |  | 77 |  |  | 176 |  |  | 93 |  |  | 107 |  |  | 200 |
Delstrigo | 14 |  |  | 70 |  |  | 83 |  |  | 14 |  |  | 45 |  |  | 60 |  |  | 29 |  |  | 121 |  |  | 150 |  |  | 26 |  |  | 89 |  |  | 116 |
Pifeltro | 25 |  |  | 16 |  |  | 41 |  |  | 27 |  |  | 12 |  |  | 39 |  |  | 57 |  |  | 29 |  |  | 86 |  |  | 56 |  |  | 25 |  |  | 81 |
Neuroscience |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Belsomra | 18 |  |  | 21 |  |  | 40 |  |  | 19 |  |  | 34 |  |  | 53 |  |  | 31 |  |  | 58 |  |  | 90 |  |  | 33 |  |  | 66 |  |  | 99 |
Immunology |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Simponi | — |  |  | — |  |  | — |  |  | — |  |  | 172 |  |  | 172 |  |  | — |  |  | — |  |  | — |  |  | — |  |  | 356 |  |  | 356 |
Remicade | — |  |  | — |  |  | — |  |  | — |  |  | 35 |  |  | 35 |  |  | — |  |  | — |  |  | — |  |  | — |  |  | 74 |  |  | 74 |
Diabetes |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Januvia | 216 |  |  | 155 |  |  | 372 |  |  | 177 |  |  | 227 |  |  | 405 |  |  | 561 |  |  | 360 |  |  | 921 |  |  | 361 |  |  | 463 |  |  | 824 |
Janumet | 68 |  |  | 184 |  |  | 251 |  |  | 17 |  |  | 208 |  |  | 224 |  |  | 133 |  |  | 366 |  |  | 498 |  |  | 55 |  |  | 420 |  |  | 475 |
Other pharmaceutical (4) | 136 |  |  | 450 |  |  | 584 |  |  | 190 |  |  | 430 |  |  | 618 |  |  | 317 |  |  | 997 |  |  | 1,313 |  |  | 354 |  |  | 899 |  |  | 1,252 |
Total Pharmaceutical segment sales | 8,328 |  |  | 5,722 |  |  | 14,050 |  |  | 7,399 |  |  | 7,009 |  |  | 14,408 |  |  | 16,254 |  |  | 11,434 |  |  | 27,688 |  |  | 14,336 |  |  | 14,079 |  |  | 28,415 |
Animal Health: |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Livestock | 190 |  |  | 771 |  |  | 961 |  |  | 168 |  |  | 669 |  |  | 837 |  |  | 384 |  |  | 1,501 |  |  | 1,885 |  |  | 334 |  |  | 1,352 |  |  | 1,686 |
Companion Animal | 309 |  |  | 376 |  |  | 685 |  |  | 287 |  |  | 358 |  |  | 645 |  |  | 617 |  |  | 732 |  |  | 1,349 |  |  | 595 |  |  | 712 |  |  | 1,307 |
Total Animal Health segment sales | 499 |  |  | 1,147 |  |  | 1,646 |  |  | 455 |  |  | 1,027 |  |  | 1,482 |  |  | 1,001 |  |  | 2,233 |  |  | 3,234 |  |  | 929 |  |  | 2,064 |  |  | 2,993 |
Total segment sales | 8,827 |  |  | 6,869 |  |  | 15,696 |  |  | 7,854 |  |  | 8,036 |  |  | 15,890 |  |  | 17,255 |  |  | 13,667 |  |  | 30,922 |  |  | 15,265 |  |  | 16,143 |  |  | 31,408 |
Other (5) | 9 |  |  | 100 |  |  | 110 |  |  | 22 |  |  | 200 |  |  | 222 |  |  | 104 |  |  | 310 |  |  | 413 |  |  | 89 |  |  | 390 |  |  | 479 |
| $ | 8,836 |  |  | $ | 6,969 |  |  | $ | 15,806 |  |  | $ | 7,876 |  |  | $ | 8,236 |  |  | $ | 16,112 |  |  | $ | 17,359 |  |  | $ | 13,977 |  |  | $ | 31,335 |  |  | $ | 15,354 |  |  | $ | 16,533 |  |  | $ | 31,887 |
U.S. plus international may not equal total due to rounding. (1) Alliance revenue for Lynparza and Lenvima represents Merck’s share of profits, which are product sales net of cost of sales and commercialization costs (see Note 3). (2) Alliance revenue for Reblozyl represents royalties (see Note 3). (3) Alliance revenue for Adempas/Verquvo represents Merck’s share of profits from sales in Bayer’s marketing territories, which are product sales net of cost of sales and commercialization costs (see Note 3). (4) Other pharmaceutical primarily reflects sales of other human health pharmaceutical products, including products within the franchises not listed separately. (5) Other is primarily comprised of miscellaneous c orpor ate revenue, including revenue hedging activities which increa se d sales by $16 million and $118 million for the six months ended June 30, 2025 and 2024, respectively, as well as revenue from third-party manufacturing arrangements (including sales to Organon & Co.). Other for the six months ended June 30, 2025 and 2024 also includes $100 million and $76 million, respectively, related to upfront and milestone payments received by Merck for out-licensing arrangements. Product sales are recorded net of the provision for discounts, including chargebacks, which are customer discounts that occur when a contracted customer purchases through an intermediary wholesale purchaser, and rebates that are owed based upon definitive contractual agreements or legal requirements with private sector and public sector (Medicaid and Medicare Part D) benefit providers, after the final dispensing of the product by a pharmacy to a benefit plan participant. These discounts, in the aggregate, reduced U.S. sales by $2.5 billion and $3.3 billion for the three months ended June 30, 2025 and 2024, respectively, and $4.7 billion and $6.6 billion for the six months ended June 30, 2025 and 2024, respectively. Consolidated sales by geographic area where derived are as follows:
| Three Months Ended June 30, |  | Six Months Ended June 30,
($ in millions) | 2025 |  | 2024 |  | 2025 |  | 2024
United States | $ | 8,836 |  |  | $ | 7,876 |  |  | $ | 17,359 |  |  | $ | 15,354 |
Europe, Middle East and Africa | 3,659 |  |  | 3,515 |  |  | 7,109 |  |  | 7,078 |
Latin America | 859 |  |  | 858 |  |  | 1,651 |  |  | 1,655 |
Asia Pacific (other than China and Japan) | 785 |  |  | 748 |  |  | 1,474 |  |  | 1,472 |
Japan | 626 |  |  | 686 |  |  | 1,295 |  |  | 1,507 |
China | 446 |  |  | 1,817 |  |  | 1,148 |  |  | 3,589 |
Other | 595 |  |  | 612 |  |  | 1,299 |  |  | 1,232 |
| $ | 15,806 |  |  | $ | 16,112 |  |  | $ | 31,335 |  |  | $ | 31,887 |
A reconciliation of segment profits to Income Before Taxes is as follows:
| Three Months Ended June 30, |  | Six Months Ended June 30,
| 2025 |  | 2024 |  | 2025 |  | 2024
($ in millions) | Pharma- ceutical |  | Animal Health |  | Total |  | Pharma- ceutical |  | Animal Health |  | Total |  | Pharma-ceutical |  | Animal Health |  | Total |  | Pharma-ceutical |  | Animal Health |  | Total
Segment sales | $ | 14,050 |  |  | $ | 1,646 |  |  | $ | 15,696 |  |  | $ | 14,408 |  |  | $ | 1,482 |  |  | $ | 15,890 |  |  | $ | 27,688 |  |  | $ | 3,234 |  |  | $ | 30,922 |  |  | $ | 28,415 |  |  | $ | 2,993 |  |  | $ | 31,408 |
Less segment costs: (1) |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Cost of sales | 1,601 |  |  | 659 |  |  |  |  | 1,708 |  |  | 612 |  |  |  |  | 3,174 |  |  | 1,258 |  |  |  |  | 3,414 |  |  | 1,225 |  |  |
Selling, general and administrative | 1,456 |  |  | 284 |  |  |  |  | 1,514 |  |  | 270 |  |  |  |  | 2,858 |  |  | 544 |  |  |  |  | 2,943 |  |  | 523 |  |  |
Research and development (2) | — |  |  | 110 |  |  |  |  | — |  |  | 91 |  |  |  |  | — |  |  | 205 |  |  |  |  | — |  |  | 181 |  |  |
Other segment items (3) | (21) |  |  | — |  |  |  |  | (14) |  |  | 1 |  |  |  |  | (70) |  |  | 1 |  |  |  |  | (46) |  |  | — |  |  |
Total segment profits | $ | 11,014 |  |  | $ | 593 |  |  | $ | 11,607 |  |  | $ | 11,200 |  |  | $ | 508 |  |  | $ | 11,708 |  |  | $ | 21,726 |  |  | $ | 1,226 |  |  | $ | 22,952 |  |  | $ | 22,104 |  |  | $ | 1,064 |  |  | $ | 23,168 |
Other profits |  |  |  |  | 30 |  |  |  |  |  |  | 129 |  |  |  |  |  |  | 231 |  |  |  |  |  |  | 274 |
Unallocated: |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Interest income |  |  |  |  | 69 |  |  |  |  |  |  | 69 |  |  |  |  |  |  | 178 |  |  |  |  |  |  | 141 |
Interest expense |  |  |  |  | (305) |  |  |  |  |  |  | (310) |  |  |  |  |  |  | (618) |  |  |  |  |  |  | (613) |
Amortization |  |  |  |  | (601) |  |  |  |  |  |  | (614) |  |  |  |  |  |  | (1,198) |  |  |  |  |  |  | (1,087) |
Depreciation |  |  |  |  | (455) |  |  |  |  |  |  | (450) |  |  |  |  |  |  | (896) |  |  |  |  |  |  | (902) |
Research and development |  |  |  |  | (3,844) |  |  |  |  |  |  | (3,360) |  |  |  |  |  |  | (7,321) |  |  |  |  |  |  | (7,209) |
Restructuring costs |  |  |  |  | (560) |  |  |  |  |  |  | (80) |  |  |  |  |  |  | (629) |  |  |  |  |  |  | (202) |
Other unallocated, net |  |  |  |  | (942) |  |  |  |  |  |  | (1,086) |  |  |  |  |  |  | (1,797) |  |  |  |  |  |  | (1,895) |
|  |  |  |  | $ | 4,999 |  |  |  |  |  |  | $ | 6,006 |  |  |  |  |  |  | $ | 10,902 |  |  |  |  |  |  | $ | 11,675 |
(1) The significant expense categories and amounts align with the segment level information that is regularly provided to the chief operating decision maker. (2) Human health-related research and development expenses incurred by Merck Research Laboratories are not allocated to segment profits as noted below. (3) Includes equity (income) loss from affiliates and other miscellaneous non-operating expenses. Pharmaceutical segment profits are comprised of segment sales less standard costs, as well as selling, general and administrative expenses directly incurred by the segment. Animal Health segment profits are comprised of segment sales, less all cost of sales, as well as selling, general and administrative expenses and research and development costs directly incurred by the segment. The chief operating decision maker (Merck’s Chief Executive Officer) uses segment profit to allocate resources predominately during the planning and forecasting process. For internal management reporting presented to the chief operating decision maker, Merck does not allocate the remaining cost of sales not included in segment profits as described above, research and development expenses incurred by Merck Research Laboratories (the Company’s research and development division that focuses on human health-related activities), or general and administrative expenses not directly incurred by the segments, nor the cost of financing these activities. Separate divisions maintain responsibility for monitoring and managing these costs, including depreciation related to fixed assets utilized by these divisions and, therefore, they are not included in segment profits. In addition, costs related to restructuring activities, as well as the amortization of intangible assets and amortization of purchase accounting adjustments are not allocated to segments. Other profits are primarily comprised of miscellaneous corporate profits, as well as operating profits (losses) related to third-party manufacturing arrangements. Other unallocated, net, includes expenses from corporate and manufacturing cost centers, intangible asset impairment charges, gains or losses on sales of businesses, expense or income related to changes in the estimated fair value measurement of liabilities for contingent consideration, and other miscellaneous income or expense items. Equity income from affiliates and depreciation included in segment profits is as follows:
| Three Months Ended June 30, |  | Six Months Ended June 30,
| 2025 |  | 2024 |  | 2025 |  | 2024
($ in millions) | Pharma- ceutical |  | Animal Health |  | Total |  | Pharma- ceutical |  | Animal Health |  | Total |  | Pharma-ceutical |  | Animal Health |  | Total |  | Pharma-ceutical |  | Animal Health |  | Total
Equity income from affiliates | $ | 29 |  |  | $ | — |  |  | $ | 29 |  |  | $ | 29 |  |  | $ | — |  |  | $ | 29 |  |  | $ | 86 |  |  | $ | — |  |  | $ | 86 |  |  | $ | 77 |  |  | $ | — |  |  | $ | 77 |
Depreciation | 1 |  |  | 62 |  |  | 63 |  |  | 1 |  |  | 67 |  |  | 68 |  |  | 2 |  |  | 122 |  |  | 124 |  |  | 2 |  |  | 125 |  |  | 127 |
Property, plant and equipment, net, by geographic area where located is as follows:
($ in millions) | June 30, 2025 |  | December 31, 2024
United States | $ | 15,182 |  |  | $ | 14,724 |
Europe, Middle East and Africa | 8,554 |  |  | 7,548 |
Asia Pacific (other than China and Japan) | 966 |  |  | 982 |
China | 204 |  |  | 202 |
Japan | 144 |  |  | 143 |
Latin America | 135 |  |  | 133 |
Other | 51 |  |  | 47 |
| $ | 25,236 |  |  | $ | 23,779 |
The Company does not disaggregate assets on a products and services basis for internal management reporting and, therefore, such information is not presented.

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- Definition The entire disclosure for reporting segments including data and tables. Reportable segments include those that meet any of the following quantitative thresholds a) it's reported revenue, including sales to external customers and intersegment sales or transfers is 10 percent or more of the combined revenue, internal and external, of all operating segments b) the absolute amount of its reported profit or loss is 10 percent or more of the greater, in absolute amount of 1) the combined reported profit of all operating segments that did not report a loss or 2) the combined reported loss of all operating segments that did report a loss c) its assets are 10 percent or more of the combined assets of all operating segments. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 21 -Subparagraph (b) -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-21 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Topic 280 -SubTopic 10 -Name 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