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Collaborative Arrangements - Daiicho Sankyo (Details) - USD ($)
$ in Millions
3 Months Ended 6 Months Ended 12 Months Ended
Jun. 30, 2025
Jun. 30, 2024
Jun. 30, 2025
Jun. 30, 2024
Dec. 31, 2023
Dec. 31, 2024
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]            
Selling, general and administrative $ 2,649 $ 2,739 $ 5,202 $ 5,221    
Research and development 4,048 3,500 7,669 7,492    
Other current assets 9,996   9,996     $ 8,706
Accrued and other current liabilities 14,502   14,502     15,694
Daiichi Sankyo | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement            
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]            
Selling, general and administrative 4 14 13 16    
Research and development 193 $ 65 321 $ 133 $ 5,500  
Other current assets 21   21     8
Accrued and other current liabilities $ 850   $ 850     $ 817