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Financial Instruments (Tables) | 9 Months Ended
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Sep. 30, 2025
Derivative Instruments and Hedging Activities Disclosure [Abstract] |
Schedule of Effect of Net Investment Hedges on OCI and the Consolidated Statement of Operations | The effects of the Company’s net investment hedges on OCI and the Condensed Consolidated Statement of Income are shown below:
| Amount of Pretax (Gain) Loss Recognized in Other Comprehensive Income (1) |  | Amount of Pretax Gain Recognized in Other (income) expense, net for Amounts Excluded from Effectiveness Testing
| Three Months Ended September 30, |  | Nine Months Ended September 30, |  | Three Months Ended September 30, |  | Nine Months Ended September 30,
($ in millions) | 2025 |  | 2024 |  | 2025 |  | 2024 |  | 2025 |  | 2024 |  | 2025 |  | 2024
Net Investment Hedging Relationships |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Foreign exchange contracts | $ | (20) |  |  | $ | 1 |  |  | $ | 45 |  |  | $ | 4 |  |  | $ | (3) |  |  | $ | — |  |  | $ | (11) |  |  | $ | (2) |
Euro-denominated notes | (1) |  |  | 169 |  |  | 540 |  |  | 73 |  |  | — |  |  | — |  |  | — |  |  | — |
(1) No amounts were reclassified from AOCL into income related to the sale of a subsidiary.
Schedule of Interest Rate Swaps Held | At September 30, 2025, the Company was a party to seven pay-floating, receive-fixed interest rate swap contracts designated as fair value hedges of a portion of fixed-rate notes as detailed in the table below.
| September 30, 2025
($ in millions) | Par Value of Debt |  | Number of Interest Rate Swaps Held |  | Total Swap Notional Amount
4.50% notes due 2033 | $ | 1,500 |  |  | 6 |  |  | $ | 1,500 |
5.00% notes due 2053 | 1,500 |  |  | 1 |  |  | 250
Schedule of Amounts Recorded on Balance Sheet Related to Fair Value Hedges | The table below presents the location of amounts recorded in the Condensed Consolidated Balance Sheet related to cumulative basis adjustments for fair value hedges:
| Carrying Amount of Hedged Liabilities |  | Cumulative Amount of Fair Value Hedging Adjustment Increase Included in the Carrying Amount
($ in millions) | September 30, 2025 |  | December 31, 2024 |  | September 30, 2025 |  | December 31, 2024
Balance Sheet Caption |  |  |  |  |  |  |
Long-Term Debt | $ | 1,819 |  |  | $ | 1,509 |  |  | $ | 80 |  |  | $ | 17 |
Schedule of Fair Value of Derivatives on a Gross Basis Segregated between those Derivatives that are Designated as Hedging Instruments and those that are Not Designated as Hedging Instruments | Presented in the table below is the fair value of derivatives on a gross basis segregated between those derivatives that are designated as hedging instruments and those that are not designated as hedging instruments:
|  | September 30, 2025 |  | December 31, 2024
|  | Fair Value of Derivative |  | U.S. Dollar Notional |  | Fair Value of Derivative |  | U.S. Dollar Notional
($ in millions) |  | Asset |  | Liability |  | Asset |  | Liability |
Derivatives Designated as Hedging Instruments | Balance Sheet Caption |  |  |  |  |  |  |  |  |  |  |
Interest rate swap contracts | Other Assets | $ | 80 |  |  | $ | — |  |  | $ | 1,750 |  |  | $ | 17 |  |  | $ | — |  |  | $ | 1,500 |
Foreign exchange contracts | Other current assets | 55 |  |  | — |  |  | 4,681 |  |  | 323 |  |  | — |  |  | 8,662 |
Foreign exchange contracts | Other Assets | 37 |  |  | — |  |  | 2,274 |  |  | 66 |  |  | — |  |  | 2,125 |
Foreign exchange contracts | Accrued and other current liabilities | — |  |  | 246 |  |  | 5,694 |  |  | — |  |  | 1 |  |  | 162 |
Foreign exchange contracts | Other Noncurrent Liabilities | — |  |  | — |  |  | — |  |  | — |  |  | 1 |  |  | 16 |
|  | $ | 172 |  |  | $ | 246 |  |  | $ | 14,399 |  |  | $ | 406 |  |  | $ | 2 |  |  | $ | 12,465 |
Derivatives Not Designated as Hedging Instruments | Balance Sheet Caption |  |  |  |  |  |  |  |  |  |  |
Foreign exchange contracts | Other current assets | $ | 144 |  |  | $ | — |  |  | $ | 12,498 |  |  | $ | 323 |  |  | $ | — |  |  | $ | 12,544 |
Foreign exchange contracts | Accrued and other current liabilities | — |  |  | 246 |  |  | 15,975 |  |  | — |  |  | 343 |  |  | 13,551 |
|  | $ | 144 |  |  | $ | 246 |  |  | $ | 28,473 |  |  | $ | 323 |  |  | $ | 343 |  |  | $ | 26,095 |
|  | $ | 316 |  |  | $ | 492 |  |  | $ | 42,872 |  |  | $ | 729 |  |  | $ | 345 |  |  | $ | 38,560 |
Schedule of Information on Derivative Positions Subject to Master Netting Arrangements as if they were Presented on a Net Basis | The following table provides information on the Company’s derivative positions subject to these master netting arrangements as if they were presented on a net basis, allowing for the right of offset by counterparty and cash collateral exchanged per the master agreements and related credit support annexes:
| September 30, 2025 |  | December 31, 2024
($ in millions) | Asset |  | Liability |  | Asset |  | Liability
Gross amounts recognized in the condensed consolidated balance sheet | $ | 316 |  |  | $ | 492 |  |  | $ | 729 |  |  | $ | 345 |
Gross amounts subject to offset in master netting arrangements not offset in the condensed consolidated balance sheet | (246) |  |  | (246) |  |  | (299) |  |  | (299) |
Cash collateral received | (1) |  |  | — |  |  | (165) |  |  | — |
Net amounts | $ | 69 |  |  | $ | 246 |  |  | $ | 265 |  |  | $ | 46 |
Schedule of Location and Amount of Pretax Gains and Losses of Derivatives | The table below provides information regarding the location and amount of pretax gains and losses of derivatives designated in fair value or cash flow hedging relationships:
| Three Months Ended September 30, |  | Nine Months Ended September 30,
($ in millions) | 2025 |  | 2024 |  | 2025 |  | 2024 |  | 2025 |  | 2024 |  | 2025 |  | 2024 |  | 2025 |  | 2024 |  | 2025 |  | 2024
Financial Statement Caption in which Effects of Fair Value or Cash Flow Hedges are Recorded | Sales |  | Other (income) expense, net (1) |  | Other comprehensive income (loss) |  | Sales |  | Other (income) expense, net (1) |  | Other comprehensive income (loss)
| $ | 17,276 |  |  | $ | 16,657 |  |  | $ | (238) |  |  | $ | (162) |  |  | $ | 219 |  |  | $ | (10) |  |  | $ | 48,611 |  |  | $ | 48,544 |  |  | $ | (281) |  |  | $ | (151) |  |  | $ | (257) |  |  | $ | (210) |
Loss (gain) on fair value hedging relationships: |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Interest rate swap contracts |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Hedged items | — |  |  | — |  |  | 4 |  |  | 68 |  |  | — |  |  | — |  |  | — |  |  | — |  |  | 62 |  |  | 42 |  |  | — |  |  | — |
Derivatives designated as hedging instruments | — |  |  | — |  |  | (5) |  |  | (69) |  |  | — |  |  | — |  |  | — |  |  | — |  |  | (63) |  |  | (43) |  |  | — |  |  | — |
Impact of cash flow hedging relationships: |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Foreign exchange contracts |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Amount of gain (loss) recognized in OCI on derivatives | — |  |  | — |  |  | — |  |  | — |  |  | 113 |  |  | (325) |  |  | — |  |  | — |  |  | — |  |  | — |  |  | (630) |  |  | 22 |
(Decrease) increase in Sales as a result of AOCL reclassifications | (85) |  |  | 48 |  |  | — |  |  | — |  |  | 85 |  |  | (48) |  |  | (35) |  |  | 146 |  |  | — |  |  | — |  |  | 35 |  |  | (146) |
Interest rate contracts |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Amount of gain recognized in Other (income) expense, net on derivatives | — |  |  | — |  |  | — |  |  | — |  |  | — |  |  | — |  |  | — |  |  | — |  |  | (1) |  |  | (1) |  |  | — |  |  | — |
Amount of gain (loss) recognized in OCI on derivatives | — |  |  | — |  |  | — |  |  | — |  |  | 18 |  |  | — |  |  | — |  |  | — |  |  | — |  |  | — |  |  | 17 |  |  | (1) |
(1) Interest expense is a component of Other (income) expense, net.
Schedule of Income Statement Effects of Derivatives Not Designated as Hedging Instruments | The table below provides information regarding the income statement effects of derivatives not designated as hedging instruments:
|  |  | Amount of Derivative Pretax Loss (Gain) Recognized in Income
|  |  | Three Months Ended September 30, |  | Nine Months Ended September 30,
($ in millions) |  |  | 2025 |  | 2024 |  | 2025 |  | 2024
Derivatives Not Designated as Hedging Instruments | Income Statement Caption |  |  |  |  |  |  |  |
Foreign exchange contracts (1) | Other (income) expense, net |  | $ | 39 |  |  | $ | (139) |  |  | $ | (217) |  |  | $ | (65) |
Foreign exchange contracts (2) | Sales |  | (8) |  |  | 10 |  |  | 26 |  |  | (10) |
(1) These derivative contracts primarily mitigate changes in the value of remeasured foreign currency denominated monetary assets and liabilities attributable to changes in foreign currency exchange rates. (2) These derivative contracts serve as economic hedges of forecasted transactions.
Schedule of Information on Investments in Debt and Equity Securities | Information on investments in debt and equity securities is as follows:
| September 30, 2025 |  | December 31, 2024
| Amortized Cost |  | Gross Unrealized |  | Fair Value |  | Amortized Cost |  | Gross Unrealized |  | Fair Value
($ in millions) | Gains |  | Losses |  | Gains |  | Losses |
U.S. government and agency securities | $ | 99 |  |  | $ | — |  |  | $ | — |  |  | $ | 99 |  |  | $ | 188 |  |  | $ | — |  |  | $ | — |  |  | $ | 188 |
Commercial paper | 45 |  |  | — |  |  | — |  |  | 45 |  |  | 348 |  |  | — |  |  | — |  |  | 348 |
Foreign government bonds | 1 |  |  | — |  |  | — |  |  | 1 |  |  | — |  |  | — |  |  | — |  |  | — |
Total debt securities | $ | 145 |  |  | $ | — |  |  | $ | — |  |  | $ | 145 |  |  | $ | 536 |  |  | $ | — |  |  | $ | — |  |  | $ | 536 |
Publicly traded equity securities (1) |  |  |  |  |  |  | 1,546 |  |  |  |  |  |  |  |  | 920 |
Total debt and publicly traded equity securities |  |  |  |  |  |  | $ | 1,691 |  |  |  |  |  |  |  |  | $ | 1,456 |
(1) Unrealized net gains of $367 million and $630 million were recorded in Other (income) expense, net in the third quarter and first nine months of 2025, respectively, on equity securities still held at September 30, 2025. Unrealized net losses (gains) of $42 million and $(82) million were recorded in Other (income) expense, net in the third quarter and first nine months of 2024, respectively, on equity securities still held at September 30, 2024.
Schedule of Financial Assets and Liabilities Measured at Fair Value on a Recurring Basis | Financial assets and liabilities measured at fair value on a recurring basis are summarized below:
| Fair Value Measurements Using |  | Fair Value Measurements Using
| Level 1 |  | Level 2 |  | Level 3 |  | Total |  | Level 1 |  | Level 2 |  | Level 3 |  | Total
($ in millions) | September 30, 2025 |  | December 31, 2024
Assets |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Investments |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Commercial paper | $ | — |  |  | $ | 45 |  |  | $ | — |  |  | $ | 45 |  |  | $ | — |  |  | $ | 348 |  |  | $ | — |  |  | $ | 348 |
Foreign government bonds | — |  |  | 1 |  |  | — |  |  | 1 |  |  | — |  |  | — |  |  | — |  |  | — |
U.S. government and agency securities | — |  |  | — |  |  | — |  |  | — |  |  | — |  |  | 99 |  |  | — |  |  | 99 |
Publicly traded equity securities | 1,116 |  |  | — |  |  | — |  |  | 1,116 |  |  | 463 |  |  | — |  |  | — |  |  | 463 |
| 1,116 |  |  | 46 |  |  | — |  |  | 1,162 |  |  | 463 |  |  | 447 |  |  | — |  |  | 910 |
Other assets (1) |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
U.S. government and agency securities | 99 |  |  | — |  |  | — |  |  | 99 |  |  | 89 |  |  | — |  |  | — |  |  | 89 |
Publicly traded equity securities (2) | 430 |  |  | — |  |  | — |  |  | 430 |  |  | 457 |  |  | — |  |  | — |  |  | 457 |
| 529 |  |  | — |  |  | — |  |  | 529 |  |  | 546 |  |  | — |  |  | — |  |  | 546 |
Derivative assets (3) |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Forward exchange contracts | — |  |  | 169 |  |  | — |  |  | 169 |  |  | — |  |  | 499 |  |  | — |  |  | 499 |
Interest rate swaps | — |  |  | 80 |  |  | — |  |  | 80 |  |  | — |  |  | 17 |  |  | — |  |  | 17 |
Purchased currency options | — |  |  | 67 |  |  | — |  |  | 67 |  |  | — |  |  | 213 |  |  | — |  |  | 213 |
| — |  |  | 316 |  |  | — |  |  | 316 |  |  | — |  |  | 729 |  |  | — |  |  | 729 |
Total assets | $ | 1,645 |  |  | $ | 362 |  |  | $ | — |  |  | $ | 2,007 |  |  | $ | 1,009 |  |  | $ | 1,176 |  |  | $ | — |  |  | $ | 2,185 |
Liabilities |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Other liabilities |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Contingent consideration | $ | — |  |  | $ | — |  |  | $ | — |  |  | $ | — |  |  | $ | — |  |  | $ | — |  |  | $ | 193 |  |  | $ | 193 |
Derivative liabilities (3) |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Forward exchange contracts | — |  |  | 461 |  |  | — |  |  | 461 |  |  | — |  |  | 338 |  |  | — |  |  | 338 |
Written currency options | — |  |  | 31 |  |  | — |  |  | 31 |  |  | — |  |  | 7 |  |  | — |  |  | 7 |
| — |  |  | 492 |  |  | — |  |  | 492 |  |  | — |  |  | 345 |  |  | — |  |  | 345 |
Total liabilities | $ | — |  |  | $ | 492 |  |  | $ | — |  |  | $ | 492 |  |  | $ | — |  |  | $ | 345 |  |  | $ | 193 |  |  | $ | 538 |
(1) Investments included in other assets are restricted as to use, including for the payment of benefits under employee benefit plans. (2) Includes securities with an aggregate fair value of $81 million at December 31, 2024, which were subject to a contractual sale restriction that expired in April 2025. (3) The fair value determination of derivatives includes the impact of the credit risk of counterparties to the derivatives and the Company’s own credit risk, the effects of which were not significant.
Schedule of Information About the Changes in Liabilities for Contingent Consideration | Summarized information about the changes in the fair value of liabilities for contingent consideration associated with business combinations is as follows:
($ in millions) | 2025 |  | 2024
Fair value January 1 | $ | 193 |  |  | $ | 354 |
Changes in estimated fair value (1) | (52) |  |  | 2 |
Payments (2) | (141) |  |  | (148) |
Fair value September 30 | $ | — |  |  | $ | 208 |
(1) Recorded in Cost of sales, Research and development expenses, and Other (income) expense, net. Includes cumulative translation adjustments. Amount in 2025 includes the reversal of $45 million for a Zerbaxa sales-based milestone as it was determined that payment was not probable. (2) Amount in both periods reflects payments related to the 2016 termination of the Sanofi Pasteur MSD joint venture. Amount in 2025 also includes a $25 million payment related to the achievement of a sales-based milestone for Zerbaxa.

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