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Collaborative Arrangements - Bayer AG (Details) - USD ($)
 3 Months Ended 9 Months Ended
Sep. 30, 2025
Sep. 30, 2024
Sep. 30, 2025
Sep. 30, 2024
Dec. 31, 2024
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Sales $ 17,276,000,000 $ 16,657,000,000 $ 48,611,000,000 $ 48,544,000,000  
Cost of sales 3,855,000,000 4,080,000,000 10,831,000,000 11,365,000,000  
Selling, general and administrative 2,633,000,000 2,731,000,000 7,835,000,000 7,952,000,000  
Research and development 4,234,000,000 5,862,000,000 11,903,000,000 13,354,000,000  
Other current assets 47,557,000,000   47,557,000,000   $ 38,782,000,000
Accrued and other current liabilities 16,186,000,000   16,186,000,000   15,694,000,000
Adempas | Licenses and Other          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Finite-lived intangible assets 312,000,000   312,000,000    
Verquvo | Licenses and Other          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Finite-lived intangible assets 41,000,000   41,000,000    
Bayer AG | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Sales milestone payments 0   0    
Revenue from collaborative arrangement 112,000,000 102,000,000 340,000,000 306,000,000  
Sales 206,000,000 185,000,000 602,000,000 545,000,000  
Cost of sales 71,000,000 59,000,000 190,000,000 182,000,000  
Selling, general and administrative 22,000,000 29,000,000 80,000,000 88,000,000  
Research and development 11,000,000 27,000,000 55,000,000 82,000,000  
Other current assets 168,000,000   168,000,000   160,000,000
Accrued and other current liabilities 93,000,000   93,000,000   $ 82,000,000
Bayer AG | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Adempas          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Sales 82,000,000 72,000,000 229,000,000 214,000,000  
Bayer AG | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Verquvo          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Sales $ 12,000,000 $ 11,000,000 $ 33,000,000 $ 25,000,000