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Collaborative Arrangements - Schedule of Daiicho Sankyo (Details) - USD ($)
$ in Millions
 3 Months Ended 9 Months Ended 12 Months Ended
Sep. 30, 2025
Sep. 30, 2024
Sep. 30, 2025
Sep. 30, 2024
Dec. 31, 2023
Dec. 31, 2024
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]            
Cost of sales $ 3,855 $ 4,080 $ 10,831 $ 11,365    
Selling, general and administrative 2,633 2,731 7,835 7,952    
Research and development 4,234 5,862 11,903 13,354    
Other current assets 10,779   10,779     $ 8,706
Accrued and other current liabilities 16,186   16,186     15,694
Daiichi Sankyo | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement            
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]            
Cost of sales 67 0 67 0    
Selling, general and administrative 8 5 21 21    
Research and development 110 $ 94 379 $ 227 $ 5,500  
Other current assets 17   17     8
Accrued and other current liabilities $ 869   $ 869     $ 817