<SEC-DOCUMENT>0001567619-22-020222.txt : 20221115
<SEC-HEADER>0001567619-22-020222.hdr.sgml : 20221115
<ACCEPTANCE-DATETIME>20221114195741
ACCESSION NUMBER:		0001567619-22-020222
CONFORMED SUBMISSION TYPE:	13F-HR
PUBLIC DOCUMENT COUNT:		2
CONFORMED PERIOD OF REPORT:	20200930
FILED AS OF DATE:		20221115
DATE AS OF CHANGE:		20221114
EFFECTIVENESS DATE:		20221115

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Alphabet Inc.
		CENTRAL INDEX KEY:			0001652044
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-COMPUTER PROGRAMMING, DATA PROCESSING, ETC. [7370]
		IRS NUMBER:				611767919
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		13F-HR
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	028-22702
		FILM NUMBER:		221388766

	BUSINESS ADDRESS:	
		STREET 1:		1600 AMPHITHEATRE PARKWAY
		CITY:			MOUNTAIN VIEW
		STATE:			CA
		ZIP:			94043
		BUSINESS PHONE:		650-253-0000

	MAIL ADDRESS:	
		STREET 1:		1600 AMPHITHEATRE PARKWAY
		CITY:			MOUNTAIN VIEW
		STATE:			CA
		ZIP:			94043
</SEC-HEADER>
<DOCUMENT>
<TYPE>13F-HR
<SEQUENCE>1
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          <cik>0001652044</cik>
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      <periodOfReport>09-30-2020</periodOfReport>
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    <coverPage>
      <reportCalendarOrQuarter>09-30-2020</reportCalendarOrQuarter>
      <filingManager>
        <name>Alphabet Inc.</name>
        <address>
          <com:street1>1600 AMPHITHEATRE PARKWAY</com:street1>
          <com:city>MOUNTAIN VIEW</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>94043</com:zipCode>
        </address>
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      <reportType>13F HOLDINGS REPORT</reportType>
      <form13FFileNumber>028-22702</form13FFileNumber>
      <provideInfoForInstruction5>N</provideInfoForInstruction5>
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    <signatureBlock>
      <name>Fabian Souza</name>
      <title>Vice President, Deputy Controller</title>
      <phone>650-253-0000</phone>
      <signature>/s/ Fabian Souza</signature>
      <city>Mountain View</city>
      <stateOrCountry>CA</stateOrCountry>
      <signatureDate>11-14-2022</signatureDate>
    </signatureBlock>
    <summaryPage>
      <otherIncludedManagersCount>4</otherIncludedManagersCount>
      <tableEntryTotal>26</tableEntryTotal>
      <tableValueTotal>2128802</tableValueTotal>
      <isConfidentialOmitted>false</isConfidentialOmitted>
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        <otherManager2>
          <sequenceNumber>1</sequenceNumber>
          <otherManager>
            <cik>0001940173</cik>
            <form13FFileNumber>028-22704</form13FFileNumber>
            <name>GV Management Company, L.L.C.</name>
          </otherManager>
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          <sequenceNumber>2</sequenceNumber>
          <otherManager>
            <cik>0001824723</cik>
            <form13FFileNumber>028-22705</form13FFileNumber>
            <name>Google LLC</name>
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        <otherManager2>
          <sequenceNumber>3</sequenceNumber>
          <otherManager>
            <cik>0001765351</cik>
            <form13FFileNumber>028-22709</form13FFileNumber>
            <name>CapitalG Rise LLC</name>
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          <sequenceNumber>4</sequenceNumber>
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            <cik>0001848282</cik>
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			<nameOfIssuer>Alector Inc</nameOfIssuer>
			<titleOfClass>COM</titleOfClass>
			<cusip>014442107</cusip>
			<value>1853</value>
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			<nameOfIssuer>Arcus Biosciences Inc</nameOfIssuer>
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			<value>86553</value>
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			<nameOfIssuer>Autolus Therapeutics PLC</nameOfIssuer>
			<titleOfClass>SPON ADS</titleOfClass>
			<cusip>05280R100</cusip>
			<value>8128</value>
			<shrsOrPrnAmt>
				<sshPrnamt>698262</sshPrnamt>
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			<nameOfIssuer>Beam Therapeutics Inc</nameOfIssuer>
			<titleOfClass>COM</titleOfClass>
			<cusip>07373V105</cusip>
			<value>16340</value>
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				<Shared>663691</Shared>
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			<nameOfIssuer>Cloudera Inc</nameOfIssuer>
			<titleOfClass>COM</titleOfClass>
			<cusip>18914U100</cusip>
			<value>4658</value>
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				<sshPrnamt>427710</sshPrnamt>
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		<infoTable>
			<nameOfIssuer>Cortexyme Inc</nameOfIssuer>
			<titleOfClass>COM</titleOfClass>
			<cusip>22053A107</cusip>
			<value>9456</value>
			<shrsOrPrnAmt>
				<sshPrnamt>189122</sshPrnamt>
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		<infoTable>
			<nameOfIssuer>Crowdstrike Hldgs Inc</nameOfIssuer>
			<titleOfClass>CL A</titleOfClass>
			<cusip>22788C105</cusip>
			<value>4260</value>
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				<sshPrnamt>31020</sshPrnamt>
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				<Shared>31020</Shared>
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			<nameOfIssuer>Dexcom Inc</nameOfIssuer>
			<titleOfClass>COM</titleOfClass>
			<cusip>252131107</cusip>
			<value>332126</value>
			<shrsOrPrnAmt>
				<sshPrnamt>805681</sshPrnamt>
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			<investmentDiscretion>DFND</investmentDiscretion>
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			<nameOfIssuer>Dropbox Inc</nameOfIssuer>
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			<cusip>26210C104</cusip>
			<value>251</value>
			<shrsOrPrnAmt>
				<sshPrnamt>13033</sshPrnamt>
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			<nameOfIssuer>Evelo Biosciences Inc</nameOfIssuer>
			<titleOfClass>COM</titleOfClass>
			<cusip>299734103</cusip>
			<value>5589</value>
			<shrsOrPrnAmt>
				<sshPrnamt>1060495</sshPrnamt>
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			<nameOfIssuer>Fulcrum Therapeutics Inc</nameOfIssuer>
			<titleOfClass>COM</titleOfClass>
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			<titleOfClass>COM</titleOfClass>
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			<nameOfIssuer>Magenta Therapeutics Inc</nameOfIssuer>
			<titleOfClass>COM</titleOfClass>
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			<nameOfIssuer>Mohawk Group Hldgs Inc</nameOfIssuer>
			<titleOfClass>COM</titleOfClass>
			<cusip>608189106</cusip>
			<value>7431</value>
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			<nameOfIssuer>Taysha Gene Therapies Inc</nameOfIssuer>
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				<None>0</None>
			</votingAuthority>
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