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Income Taxes (Details) - USD ($)
$ in Millions
3 Months Ended 6 Months Ended
Jun. 30, 2019
Jun. 30, 2018
Jun. 30, 2019
Jun. 30, 2018
Operating Loss Carryforwards [Line Items]        
Effective income tax rate, percentage 9.50%   14.10% 33.50%
Income tax expense $ 138.7 $ 273.3 $ 308.7 $ 471.8
Income before income taxes 1,465.9 41.7 $ 2,197.0 $ 1,407.4
Tax Year 2013        
Operating Loss Carryforwards [Line Items]        
Income tax year under examination     2013  
Tax Year 2015        
Operating Loss Carryforwards [Line Items]        
Income tax year under examination     2015  
Decrease in unrecognized tax benefits is reasonably possible 100.0   $ 100.0  
Tax Years 2013 to 2015        
Operating Loss Carryforwards [Line Items]        
Decrease in unrecognized tax benefits is reasonably possible 200.0   $ 200.0  
Income tax settlement payment $ 125.0      
ARMO and AurKa        
Operating Loss Carryforwards [Line Items]        
Nondeductible expense, research and development, amount   $ 1,560.0