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Revenue (Disaggregation of Revenue by Product) (Details) - USD ($) $ in Millions | 12 Months Ended
--- | ---
Dec. 31, 2020 | Dec. 31, 2019 | Dec. 31, 2018
Disaggregation of Revenue [Line Items] |  |  |
Revenue | $ 24,539.8 | $ 22,319.5 | $ 21,493.3
U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 14,229.3 | 12,722.6 | 12,391.9
Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 10,310.5 | 9,596.8 | 9,101.4
Diabetes | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 7,909.1 | 7,529.5 | 6,607.0
Diabetes | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 3,925.3 | 3,602.6 | 3,212.5
Trulicity® | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 3,835.9 | 3,155.2 | 2,515.8
Trulicity® | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 1,232.2 | 972.7 | 683.3
Humalog® | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 1,485.6 | 1,669.7 | 1,787.8
Humalog® | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 1,140.3 | 1,151.0 | 1,208.7
Humulin® | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 866.4 | 879.7 | 910.2
Humulin® | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 393.2 | 410.4 | 421.2
Jardiance® |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 1,153.8 | 944.2 | 658.3
Jardiance® | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 620.8 | 565.9 | 400.2
Jardiance® | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 533.0 | 378.3 | 258.1
Basaglar® |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 1,124.4 | 1,112.6 | 801.2
Basaglar® | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 842.3 | 876.2 | 622.8
Basaglar® | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 282.1 | 236.3 | 178.5
Trajenta® |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 358.5 | 590.6 | 574.7
Trajenta® | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 95.6 | 224.8 | 224.2
Trajenta® | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 263.0 | 365.8 | 350.5
Other Diabetes | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 162.5 | 158.0 | 146.0
Other Diabetes | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 81.5 | 88.1 | 112.2
Oncology | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 2,792.1 | 2,608.5 | 2,403.2
Oncology | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 2,527.2 | 2,005.9 | 1,857.3
Alimta® | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 1,265.3 | 1,219.5 | 1,131.0
Alimta® | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 1,064.7 | 896.4 | 1,001.9
Cyramza® | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 381.9 | 335.3 | 291.5
Cyramza® | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 650.8 | 589.9 | 529.9
Verzenio® | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 618.2 | 454.8 | 248.5
Verzenio® | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 294.4 | 124.9 | 6.6
Erbitux® | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 480.1 | 487.9 | 531.6
Erbitux® | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 56.3 | 55.4 | 103.8
Other Oncology | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 46.6 | 111.0 | 200.6
Other Oncology | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 461.0 | 339.3 | 215.1
Immunology | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 1,372.3 | 1,059.0 | 745.4
Immunology | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 1,089.6 | 734.3 | 394.6
Taltz® | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 1,288.5 | 1,016.8 | 738.7
Taltz® | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 500.0 | 349.6 | 198.7
Olumiant® |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 638.9 | 426.9 | 202.5
Olumiant® | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 63.8 | 42.2 | 6.7
Olumiant® | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 575.0 | 384.7 | 195.9
Other Immunology | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 20.0 | 0.0 | 0.0
Other Immunology | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 14.6 | 0.0 | 0.0
Neuroscience | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 487.3 | 356.5 | 277.4
Neuroscience | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 1,344.0 | 1,366.4 | 1,543.3
Cymbalta® | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 42.1 | 49.6 | 54.3
Cymbalta® | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 725.6 | 675.8 | 653.7
Zyprexa® | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 46.1 | 41.0 | 36.2
Zyprexa® | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 360.5 | 377.6 | 435.1
Emgality® | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 325.9 | 154.9 | 4.9
Emgality® | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 37.0 | 7.7 | 0.0
Other Neuroscience | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 73.2 | 111.0 | 182.0
Other Neuroscience | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 220.9 | 305.3 | 454.5
Other | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 1,668.4 | 1,169.1 | 2,358.8
Other | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 1,424.4 | 1,887.7 | 2,093.7
Forteo® | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 510.3 | 645.5 | 757.9
Forteo® | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 536.0 | 759.1 | 817.7
Bamlanivimab |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 871.2 |  |
Bamlanivimab | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 850.0 | 0.0 | 0.0
Bamlanivimab | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 21.2 | 0.0 | 0.0
Cialis® | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 61.8 | 231.7 | 1,129.2
Cialis® | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 545.4 | 658.8 | 722.7
Other | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 246.4 | 291.9 | 471.8
Other | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | $ 321.8 | $ 469.7 | $ 553.3

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