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Income Taxes (Schedule of Reconciliation of Income Taxes) (Details) - USD ($) $ in Millions | 12 Months Ended
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Dec. 31, 2020 | Dec. 31, 2019 | Dec. 31, 2018
Income Tax Disclosure [Abstract] |  |  |
Income tax at the U.S. federal statutory tax rate | $ 1,518.3 | $ 1,105.8 | $ 772.8
Add (deduct): |  |  |
International operations, including Puerto Rico | (297.1) | (242.0) | (627.1)
General business credits | (97.9) | (108.8) | (87.4)
Non-deductible acquired IPR&D | 63.2 | 0.0 | 309.9
2017 Tax Act | 0.0 | 0.0 | 175.3
Other | (150.3) | (127.0) | (14.0)
Income taxes | $ 1,036.2 | $ 628.0 | $ 529.5

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- Definition Amount of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to nondeductible research and development expense. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 12 -URI http://asc.fasb.org/extlink&oid=84230637&loc=d3e32687-109319 + Details
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