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Goodwill and Other Intangibles (Tables) | 12 Months Ended
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Dec. 31, 2021
Goodwill and Intangible Assets Disclosure [Abstract] |
Schedule of Finite-lived Intangible Assets other than Goodwill | The components of intangible assets other than goodwill at December 31 were as follows:
| 2021 |  | 2020
Description | Carrying Amount, Gross |  | Accumulated Amortization |  | Carrying Amount, Net |  | Carrying Amount, Gross |  | Accumulated Amortization |  | Carrying Amount, Net
Finite-lived intangible assets: |  |  |  |  |  |  |  |  |  |  |
Marketed products | $ | 7,987.2 |  |  | $ | (2,229.2) |  |  | $ | 5,758.0 |  |  | $ | 7,984.0 |  |  | $ | (1,659.5) |  |  | $ | 6,324.5 |
Other | 69.4 |  |  | (60.5) |  |  | 8.9 |  |  | 92.8 |  |  | (68.3) |  |  | 24.5 |
Total finite-lived intangible assets | 8,056.6 |  |  | (2,289.7) |  |  | 5,766.9 |  |  | 8,076.8 |  |  | (1,727.8) |  |  | 6,349.0 |
Indefinite-lived intangible assets: |  |  |  |  |  |  |  |  |  |  |
Acquired IPR&D | 1,925.0 |  |  | — |  |  | 1,925.0 |  |  | 1,101.0 |  |  | — |  |  | 1,101.0 |
Other intangibles | $ | 9,981.6 |  |  | $ | (2,289.7) |  |  | $ | 7,691.9 |  |  | $ | 9,177.8 |  |  | $ | (1,727.8) |  |  | $ | 7,450.0 |
Schedule of Indefinite-lived Intangible Assets other than Goodwill | The components of intangible assets other than goodwill at December 31 were as follows:
| 2021 |  | 2020
Description | Carrying Amount, Gross |  | Accumulated Amortization |  | Carrying Amount, Net |  | Carrying Amount, Gross |  | Accumulated Amortization |  | Carrying Amount, Net
Finite-lived intangible assets: |  |  |  |  |  |  |  |  |  |  |
Marketed products | $ | 7,987.2 |  |  | $ | (2,229.2) |  |  | $ | 5,758.0 |  |  | $ | 7,984.0 |  |  | $ | (1,659.5) |  |  | $ | 6,324.5 |
Other | 69.4 |  |  | (60.5) |  |  | 8.9 |  |  | 92.8 |  |  | (68.3) |  |  | 24.5 |
Total finite-lived intangible assets | 8,056.6 |  |  | (2,289.7) |  |  | 5,766.9 |  |  | 8,076.8 |  |  | (1,727.8) |  |  | 6,349.0 |
Indefinite-lived intangible assets: |  |  |  |  |  |  |  |  |  |  |
Acquired IPR&D | 1,925.0 |  |  | — |  |  | 1,925.0 |  |  | 1,101.0 |  |  | — |  |  | 1,101.0 |
Other intangibles | $ | 9,981.6 |  |  | $ | (2,289.7) |  |  | $ | 7,691.9 |  |  | $ | 9,177.8 |  |  | $ | (1,727.8) |  |  | $ | 7,450.0 |
Finite-lived Intangible Assets Amortization Expense | Amortization expense related to finite-lived intangible assets was as follows:
| 2021 |  | 2020 |  | 2019
Amortization expense | $ | 628.8 |  |  | $ | 428.2 |  |  | $ | 225.8 |
Schedule of Finite-Lived Intangible Assets, Future Amortization Expense | The estimated amortization expense for each of the next five years associated with our finite-lived intangible assets as of December 31, 2021 is as follows:
| 2022 |  | 2023 |  | 2024 |  | 2025 |  | 2026
Estimated amortization expense | $ | 570.9 |  |  | $ | 483.5 |  |  | $ | 433.7 |  |  | $ | 417.1 |  |  | $ | 408.8 |

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