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Acquisitions and Divestiture (Purchase Price Allocation) (Details) - USD ($) $ in Millions |  |  | 1 Months Ended | 12 Months Ended |
--- | --- | --- | --- | --- | ---
Jan. 22, 2021 | Feb. 15, 2019 | Jan. 31, 2021 | Dec. 31, 2021 | Dec. 31, 2020 | Dec. 31, 2019 | Jun. 30, 2019
Business Acquisition [Line Items] |  |  |  |  |  |  |
Goodwill |  |  |  | $ 3,892.0 | $ 3,766.5 |  |
Cash paid, net of cash acquired |  |  |  | $ 747.4 | $ 849.3 | $ 6,917.7 |
Prevail Therapeutics Inc. |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |
Cash | $ 90.5 |  |  |  |  |  |
Acquired IPR&D | 824.0 |  |  |  |  |  |
Goodwill | 126.8 |  |  |  |  |  |
Deferred income taxes | (106.0) |  |  |  |  |  |
Other assets and liabilities, net | (31.5) |  |  |  |  |  |
Acquisition date fair value of consideration transferred | 903.8 |  |  |  |  |  |
Cash acquired | (90.5) |  |  |  |  |  |
Fair value of CVR liability | (65.9) |  |  |  |  |  |
Cash paid, net of cash acquired | $ 747.4 |  | $ 747.4 |  |  |  |
Loxo Oncology, Inc. |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |
Acquired IPR&D |  | $ 4,670.0 |  |  |  |  |
Finite-lived intangibles |  | 980.0 |  |  |  |  |
Goodwill |  | 2,326.9 |  |  |  |  |
Deferred income taxes |  | (1,032.8) |  |  |  |  |
Other assets and liabilities, net |  | (26.4) |  |  |  |  |
Acquisition date fair value of consideration transferred |  | 6,917.7 |  |  |  |  |
Total identifiable net assets |  | $ 4,590.8 |  |  |  |  |
Contract-based intangibles | Loxo Oncology, Inc. |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |
Weighted average useful life |  | 12 years |  |  |  |  |
Selpercatinib (LOXO-292) | Loxo Oncology, Inc. |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |
Acquired IPR&D |  | $ 4,600.0 |  |  |  |  | $ 4,600.0

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