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Collaborations and Other Arrangements (Milestones (Deferred) Capitalized) (Details) - Milestone Payments, Development and Regulatory, Capitalized (Deferred), Cumulative - USD ($) $ in Millions | Dec. 31, 2021 | Dec. 31, 2020
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Jardiance® |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |
Milestones payments | $ 136.1 | $ 156.2
Trajenta® |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |
Milestones payments | 88.5 | 114.6
Basaglar® |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |
Milestones payments | $ (149.3) | $ (168.0)

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- Definition Collaborative Arrangement, Rights And Obligations, Rights (Obligations) + References No definition available. + Details
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Namespace Prefix: | lly_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | instant

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- Definition Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. + References No definition available. + Details
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Namespace Prefix: | us-gaap_
Data Type: | xbrli:stringItemType
Balance Type: | na
Period Type: | duration

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- Details
Name: | us-gaap_TypeOfArrangementAxis=lly_MilestonePaymentsDevelopmentandRegulatoryCapitalizedDeferredCumulativeMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

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- Details
Name: | srt_ProductOrServiceAxis=lly_JardianceMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

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- Details
Name: | srt_ProductOrServiceAxis=lly_TrajentaBIMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

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- Details
Name: | srt_ProductOrServiceAxis=lly_BasaglarMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |