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Revenue (Tables) | 12 Months Ended
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Dec. 31, 2021
Revenue from Contract with Customer [Abstract] |
Schedule of Disaggregation of Revenue | The following table summarizes our revenue recognized in our consolidated statements of operations:
| 2021 |  | 2020 |  | 2019
Net product revenue | $ | 25,957.9 |  |  | $ | 22,694.8 |  |  | $ | 20,377.3 |
Collaboration and other revenue(1) | 2,360.5 |  |  | 1,845.0 |  |  | 1,942.2 |
Revenue | $ | 28,318.4 |  |  | $ | 24,539.8 |  |  | $ | 22,319.5 |
(1) Collaboration and other revenue associated with prior period transfers of intellectual property was $175.0 million, $135.6 million, and $301.5 million during the years ended December 31, 2021, 2020, and 2019, respectively. The following table summarizes revenue by product:
|  |  | U.S. |  | Outside U.S.
|  |  | 2021 |  | 2020 |  | 2019 |  | 2021 |  | 2020 |  | 2019
Revenue—to unaffiliated customers: |  |  |  |  |  |  |  |  |  |
Diabetes: |  |  |  |  |  |  |  |  |  |  |
Trulicity® | $ | 4,914.4 |  |  | $ | 3,835.9 |  |  | $ | 3,155.2 |  |  | $ | 1,557.6 |  |  | $ | 1,232.2 |  |  | $ | 972.7 |
Humalog® (1) | 1,320.7 |  |  | 1,485.6 |  |  | 1,669.7 |  |  | 1,132.3 |  |  | 1,140.3 |  |  | 1,151.0 |
Jardiance (2) | 807.3 |  |  | 620.8 |  |  | 565.9 |  |  | 683.5 |  |  | 533.0 |  |  | 378.3 |
Humulin® | 832.9 |  |  | 866.4 |  |  | 879.7 |  |  | 389.6 |  |  | 393.2 |  |  | 410.4 |
Basaglar® | 588.3 |  |  | 842.3 |  |  | 876.2 |  |  | 304.2 |  |  | 282.1 |  |  | 236.3 |
Trajenta (3) | 82.1 |  |  | 95.6 |  |  | 224.8 |  |  | 290.4 |  |  | 263.0 |  |  | 365.8 |
Other Diabetes | 173.6 |  |  | 162.5 |  |  | 158.0 |  |  | 111.2 |  |  | 81.5 |  |  | 88.1 |
Total Diabetes | 8,719.3 |  |  | 7,909.1 |  |  | 7,529.5 |  |  | 4,468.8 |  |  | 3,925.3 |  |  | 3,602.6 |
Oncology: |  |  |  |  |  |  |  |  |  |  |
Alimta® | 1,233.9 |  |  | 1,265.3 |  |  | 1,219.5 |  |  | 827.5 |  |  | 1,064.7 |  |  | 896.4 |
Verzenio® | 834.9 |  |  | 618.2 |  |  | 454.8 |  |  | 515.0 |  |  | 294.4 |  |  | 124.9 |
Cyramza® | 358.1 |  |  | 381.9 |  |  | 335.3 |  |  | 674.8 |  |  | 650.8 |  |  | 589.9 |
Erbitux® | 481.8 |  |  | 480.1 |  |  | 487.9 |  |  | 66.4 |  |  | 56.3 |  |  | 55.4 |
Tyvyt® | — |  |  | — |  |  | — |  |  | 418.1 |  |  | 308.7 |  |  | 134.0 |
Other Oncology | 120.1 |  |  | 46.6 |  |  | 111.0 |  |  | 210.7 |  |  | 152.3 |  |  | 205.3 |
Total Oncology | 3,028.8 |  |  | 2,792.1 |  |  | 2,608.5 |  |  | 2,712.5 |  |  | 2,527.2 |  |  | 2,005.9 |
Immunology: |  |  |  |  |  |  |  |  |  |  |
Taltz® | 1,542.4 |  |  | 1,288.5 |  |  | 1,016.8 |  |  | 670.4 |  |  | 500.0 |  |  | 349.6 |
Olumiant® (4) | 324.1 |  |  | 63.8 |  |  | 42.2 |  |  | 791.0 |  |  | 575.0 |  |  | 384.7 |
Other Immunology | 15.3 |  |  | 20.0 |  |  | — |  |  | 17.6 |  |  | 14.6 |  |  | — |
Total Immunology | 1,881.8 |  |  | 1,372.3 |  |  | 1,059.0 |  |  | 1,479.0 |  |  | 1,089.6 |  |  | 734.3 |
Neuroscience: |  |  |  |  |  |  |  |  |  |  |
Cymbalta® | 38.7 |  |  | 42.1 |  |  | 49.6 |  |  | 542.8 |  |  | 725.6 |  |  | 675.8 |
Emgality® | 434.5 |  |  | 325.9 |  |  | 154.9 |  |  | 142.7 |  |  | 37.0 |  |  | 7.7 |
Zyprexa® | 39.6 |  |  | 46.1 |  |  | 41.0 |  |  | 390.7 |  |  | 360.5 |  |  | 377.6 |
Other Neuroscience | 102.0 |  |  | 73.2 |  |  | 111.0 |  |  | 207.5 |  |  | 220.9 |  |  | 305.3 |
Total Neuroscience | 614.8 |  |  | 487.3 |  |  | 356.5 |  |  | 1,283.7 |  |  | 1,344.0 |  |  | 1,366.4 |
Other: |  |  |  |  |  |  |  |  |  |  |
COVID-19 Antibodies (5) | 1,978.0 |  |  | 850.0 |  |  | — |  |  | 261.4 |  |  | 21.2 |  |  | — |
Forteo® | 441.6 |  |  | 510.3 |  |  | 645.5 |  |  | 360.3 |  |  | 536.0 |  |  | 759.1 |
Cialis® | 10.6 |  |  | 61.8 |  |  | 231.7 |  |  | 707.9 |  |  | 545.4 |  |  | 658.8 |
Other | 136.1 |  |  | 246.4 |  |  | 291.9 |  |  | 233.9 |  |  | 321.8 |  |  | 469.7 |
Total Other | 2,566.4 |  |  | 1,668.4 |  |  | 1,169.1 |  |  | 1,563.5 |  |  | 1,424.4 |  |  | 1,887.7 |
Revenue | $ | 16,811.0 |  |  | $ | 14,229.3 |  |  | $ | 12,722.6 |  |  | $ | 11,507.4 |  |  | $ | 10,310.5 |  |  | $ | 9,596.8 |
Numbers may not add due to rounding. (1) Humalog revenue includes insulin lispro. (2) Jardiance revenue includes Glyxambi®, Synjardy®, and Trijardy® XR. (3) Trajenta revenue includes Jentadueto®. (4) Olumiant revenue includes sales for baricitinib, for treatment in hospitalized COVID-19 patients, that were made pursuant to Emergency Use Authorization (EUA) or similar regulatory authorizations. (5) COVID-19 antibodies include sales for bamlanivimab administered alone as well as sales for bamlanivimab and etesevimab administered together and were made pursuant to EUAs or similar regulatory authorizations. The following table summarizes revenue by geographical area:
|  |  |  | 2021 |  | 2020 |  | 2019
Revenue—to unaffiliated customers(1): |  |  |  |  |  |
U.S. |  | $ | 16,811.0 |  |  | $ | 14,229.3 |  |  | $ | 12,722.6 |
Europe |  | 4,776.8 |  |  | 4,187.7 |  |  | 3,765.0 |
Japan |  | 2,367.0 |  |  | 2,583.1 |  |  | 2,547.6 |
China |  | 1,661.4 |  |  | 1,116.9 |  |  | 939.4 |
Other foreign countries |  | 2,702.2 |  |  | 2,422.7 |  |  | 2,344.9 |
Revenue |  | $ | 28,318.4 |  |  | $ | 24,539.8 |  |  | $ | 22,319.5 |
Numbers may not add due to rounding. (1) Revenue is attributed to the countries based on the location of the customer.
Schedule of Amounts Recorded for Contract Liabilities | The following table summarizes contract liability balances:
| 2021 |  | 2020
Contract liabilities | $ | 262.6 |  |  | $ | 276.8 |

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