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Goodwill and Other Intangibles (Tables)
12 Months Ended
Dec. 31, 2021
Goodwill and Intangible Assets Disclosure [Abstract]  
Schedule of Finite-lived Intangible Assets other than Goodwill
The components of intangible assets other than goodwill at December 31 were as follows:
 20212020
DescriptionCarrying
Amount,
Gross
Accumulated
Amortization
Carrying
Amount,
Net
Carrying
Amount,
Gross
Accumulated
Amortization
Carrying
Amount,
Net
Finite-lived intangible assets:
Marketed products$7,987.2 $(2,229.2)$5,758.0 $7,984.0 $(1,659.5)$6,324.5 
Other69.4 (60.5)8.9 92.8 (68.3)24.5 
Total finite-lived intangible assets8,056.6 (2,289.7)5,766.9 8,076.8 (1,727.8)6,349.0 
Indefinite-lived intangible assets:
Acquired IPR&D1,925.0  1,925.0 1,101.0 — 1,101.0 
Other intangibles$9,981.6 $(2,289.7)$7,691.9 $9,177.8 $(1,727.8)$7,450.0 
Schedule of Indefinite-lived Intangible Assets other than Goodwill
The components of intangible assets other than goodwill at December 31 were as follows:
 20212020
DescriptionCarrying
Amount,
Gross
Accumulated
Amortization
Carrying
Amount,
Net
Carrying
Amount,
Gross
Accumulated
Amortization
Carrying
Amount,
Net
Finite-lived intangible assets:
Marketed products$7,987.2 $(2,229.2)$5,758.0 $7,984.0 $(1,659.5)$6,324.5 
Other69.4 (60.5)8.9 92.8 (68.3)24.5 
Total finite-lived intangible assets8,056.6 (2,289.7)5,766.9 8,076.8 (1,727.8)6,349.0 
Indefinite-lived intangible assets:
Acquired IPR&D1,925.0  1,925.0 1,101.0 — 1,101.0 
Other intangibles$9,981.6 $(2,289.7)$7,691.9 $9,177.8 $(1,727.8)$7,450.0 
Finite-lived Intangible Assets Amortization Expense
Amortization expense related to finite-lived intangible assets was as follows:
202120202019
Amortization expense$628.8 $428.2 $225.8 
Schedule of Finite-Lived Intangible Assets, Future Amortization Expense
The estimated amortization expense for each of the next five years associated with our finite-lived intangible assets as of December 31, 2021 is as follows:
20222023202420252026
Estimated amortization expense$570.9 $483.5 $433.7 $417.1 $408.8