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Acquisitions and Divestiture (Narrative) (Details) $ / shares in Units, $ in Millions		1 Months Ended				3 Months Ended	12 Months Ended
	Jan. 22, 2021 USD ($)	Jan. 31, 2021 USD ($) right $ / shares	Feb. 29, 2020 USD ($)	Oct. 31, 2019 USD ($) medicine	Feb. 28, 2019 USD ($)	Dec. 31, 2019 USD ($)	Dec. 31, 2021 USD ($)	Dec. 31, 2020 USD ($)	Dec. 31, 2019 USD ($)	Jun. 30, 2019 USD ($)	Feb. 15, 2019 USD ($)
Business Acquisition [Line Items]
Acquired IPR&D charges							$ 874.9	$ 660.4	$ 239.6
Cash paid, net of cash acquired							747.4	849.3	6,917.7
Goodwill							3,892.0	3,766.5
Repayments of long-term debt							1,905.4	276.5	2,866.4
Gain related to disposition							$ 0.0	0.0	$ 309.8
Prevail Therapeutics Inc.
Business Acquisition [Line Items]
Business acquisition, share price (in dollars per share) | $ / shares		$ 22.50
Cash paid, net of cash acquired	$ 747.4	$ 747.4
Number of contingent value rights | right		1
Contingent value right, additional price per share (in dollars per share) | $ / shares		$ 4.00
Contingent value right, additional price per share, aggregate amount		$ 160.0
Contingent value right, monthly reduction | $ / shares		$ 0.083
Goodwill	126.8
Acquired IPR&D	824.0
Deferred income tax liabilities assumed	$ 106.0
Dermira
Business Acquisition [Line Items]
Consideration transferred			$ 849.3
Goodwill			86.8
Acquired IPR&D			1,200.0
Deferred income tax liabilities assumed			49.5
Long-term debt assumed			$ 375.5
Repayments of long-term debt								$ 276.2
Loxo Oncology, Inc.
Business Acquisition [Line Items]
Consideration transferred					$ 6,920.0
Goodwill											$ 2,326.9
Acquired IPR&D											4,670.0
Deferred income tax liabilities assumed											1,032.8
Loxo Oncology, Inc. | Selpercatinib (LOXO-292)
Business Acquisition [Line Items]
Acquired IPR&D										$ 4,600.0	$ 4,600.0
Disposal Group, Disposed of by Sale, Not Discontinued Operations | Legacy Antibiotic Medicines and a Manufacturing Facility in Suzhou, China | Eddingpharm
Business Acquisition [Line Items]
Number of legacy antibiotic medicines rights sold | medicine				2
Proceeds from divestiture of businesses, net of cash divested				$ 354.8
Disposal group, not discontinued operation, payment to be received				$ 40.3
Gain related to disposition						$ 309.8

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