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Property and Equipment (Tables)
12 Months Ended
Dec. 31, 2022
Property, Plant and Equipment [Abstract]  
Property, Plant and Equipment
At December 31, property and equipment consisted of the following:
20222021
Land$256.6 $258.7 
Buildings7,915.9 7,588.1 
Equipment9,406.3 8,937.2 
Construction in progress2,798.6 2,177.8 
20,377.4 18,961.8 
Less accumulated depreciation(10,233.4)(9,976.7)
Property and equipment, net$10,144.0 $8,985.1 
Depreciation expense related to property and equipment was as follows:
202220212020
Depreciation expense$816.6 $787.0 $765.2 
Long-lived Assets by Geographic Areas
The following table summarizes long-lived assets by geographical area:
20222021
Long-lived assets(1):
U.S. and Puerto Rico$7,709.7 $6,620.0 
Ireland1,898.5 1,702.3 
Other foreign countries1,625.9 1,691.0 
Long-lived assets$11,234.1 $10,013.3 
(1) Long-lived assets consist of property and equipment, net, operating lease assets, and certain other noncurrent assets.