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Revenue (Summary of Revenue Recognized) (Details) - USD ($) $ in Millions	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Disaggregation of Revenue [Line Items]
Revenues	$ 28,541.4	$ 28,318.4	$ 24,539.8
Net product revenue
Disaggregation of Revenue [Line Items]
Revenues	25,462.8	25,957.9	22,694.8
Collaboration and other revenue
Disaggregation of Revenue [Line Items]
Revenues	3,078.6	2,360.5	1,845.0
Collaboration and other revenue associated with prior period transfers of intellectual property
Disaggregation of Revenue [Line Items]
Revenues	$ 163.4	$ 175.0	$ 135.6

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Amount of revenue recognized from goods sold, services rendered, insurance premiums, or other activities that constitute an earning process. Includes, but is not limited to, investment and interest income before deduction of interest expense when recognized as a component of revenue, and sales and trading gain (loss).

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