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Acquisitions (Narrative) (Details) $ / shares in Units, $ in Millions		1 Months Ended			12 Months Ended
	Jan. 22, 2021 USD ($)	Dec. 31, 2022 USD ($) right $ / shares	Jan. 31, 2021 USD ($) right $ / shares	Feb. 29, 2020 USD ($)	Dec. 31, 2022 USD ($) $ / shares	Dec. 31, 2021 USD ($)	Dec. 31, 2020 USD ($)	Dec. 01, 2022 USD ($)
Business Acquisition [Line Items]
Acquired in-process research and development and development milestones					$ 908.5	$ 970.1	$ 769.8
Cash paid, net of cash acquired					327.2	747.4	849.3
Goodwill		$ 4,073.0			4,073.0	3,892.0
Repayments of long-term debt					1,560.0	$ 1,905.4	$ 276.5
Acquired IPR&D Expense					$ 333.8
Akouos Acquisition
Business Acquisition [Line Items]
Business acquisition, share price (in dollars per share) | $ / shares		$ 12.50			$ 12.50
Cash paid, net of cash acquired		$ 327.2
Consideration transferred, number of contingent value rights | right		1
Contingent value right, additional price per share (in dollars per share) | $ / shares		$ 3.00			$ 3.00
Contingent value right, additional price per share, aggregate amount		$ 122.0			$ 122.0
Goodwill								$ 181.2
Acquired IPR&D								$ 184.0
Prevail Therapeutics Inc.
Business Acquisition [Line Items]
Business acquisition, share price (in dollars per share) | $ / shares			$ 22.50
Cash paid, net of cash acquired	$ 747.4		$ 747.4
Consideration transferred, number of contingent value rights | right			1
Contingent value right, additional price per share (in dollars per share) | $ / shares			$ 4.00
Contingent value right, additional price per share, aggregate amount			$ 160.0
Contingent value right, monthly reduction | $ / shares			$ 0.083
Goodwill	126.8
Acquired IPR&D	824.0
Deferred tax liabilities	$ 106.0
Dermira
Business Acquisition [Line Items]
Consideration transferred				$ 849.3
Goodwill				86.8
Acquired IPR&D				1,200.0
Deferred tax liabilities				49.5
Long-term debt assumed				375.5
Repayments of long-term debt				$ 276.2

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