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Collaborations and Other Arrangements (Narrative) (Details) - USD ($) $ in Millions	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Revenues	$ 28,541.4	$ 28,318.4	$ 24,539.8
Olumiant®
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Revenues	$ 830.5	1,115.1	638.9
Olumiant® | Royalty Payments Received
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Collaborative arrangement, rights and obligations percent (up to)	20.00%
Olumiant® | Milestone Payments, Development and Regulatory, Capitalized (Deferred), Cumulative
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Potential achievements	$ 330.0	260.0
Olumiant® | Milestone Payments, Development and Regulatory
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Potential achievements	100.0
COVID-19 Antibodies
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Revenues	2,020.0	$ 2,240.0	$ 871.2
Lebrikizumab | Milestone Payments, Development and Regulatory
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Potential achievements	65.0
Lebrikizumab | Milestone Payments, Development and Regulatory | Roche
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Potential achievements	165.0
Lebrikizumab | Milestone Payments, Sales-based
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Potential achievements	1,250.0
Lebrikizumab | Milestone Payments, Sales-based | Roche
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Potential achievements	$ 1,030.0

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Description of rights and obligations under the collaborative arrangements, including but not limited to - percent share in various revenues and costs, percent interest earned on related party notes.

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