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Revenue (Disaggregation of Revenue by Product) (Details) - USD ($) $ in Millions | 12 Months Ended
--- | ---
Dec. 31, 2023 | Dec. 31, 2022 | Dec. 31, 2021
Disaggregation of Revenue [Line Items] |  |  |
Revenue | $ 34,124.1 | $ 28,541.4 | $ 28,318.4
U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 21,791.0 | 18,190.0 | 16,811.0
Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 12,333.1 | 10,351.3 | 11,507.4
Diabetes and Obesity | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 14,780.8 | 9,911.1 | 8,719.3
Diabetes and Obesity | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 4,886.8 | 4,553.7 | 4,468.8
Trulicity® | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 5,433.3 | 5,688.8 | 4,914.4
Trulicity® | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 1,699.2 | 1,750.9 | 1,557.6
Mounjaro® | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 4,834.2 | 366.6 | 0.0
Mounjaro® | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 328.9 | 115.9 | 0.0
Jardiance |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 2,744.7 | 2,066.0 | 1,490.8
Jardiance | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 1,600.4 | 1,194.5 | 807.3
Jardiance | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 1,144.2 | 871.5 | 683.5
Humalog® | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 863.2 | 1,191.9 | 1,320.7
Humalog® | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 800.2 | 868.7 | 1,132.3
Humulin® | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 610.1 | 730.2 | 832.9
Humulin® | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 242.0 | 289.2 | 389.6
Basaglar |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 728.3 | 760.4 | 892.5
Basaglar | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 443.1 | 470.7 | 588.3
Basaglar | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 285.2 | 289.7 | 304.2
Baqsimi | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 645.7 | 110.4 | 96.4
Baqsimi | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 31.9 | 28.9 | 16.8
Zepbound® | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 175.8 | 0.0 | 0.0
Zepbound® | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 0.0 | 0.0 | 0.0
Other diabetes and obesity | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 175.0 | 158.0 | 159.3
Other diabetes and obesity | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 355.2 | 338.9 | 384.8
Oncology | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 3,797.0 | 3,218.1 | 3,028.8
Oncology | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 2,861.3 | 2,448.1 | 2,712.5
Verzenio® | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 2,509.0 | 1,653.2 | 834.9
Verzenio® | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 1,354.3 | 830.3 | 515.0
Cyramza® | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 402.3 | 351.4 | 358.1
Cyramza® | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 572.4 | 620.0 | 674.8
Erbitux® | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 528.9 | 500.1 | 481.8
Erbitux® | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 67.6 | 66.4 | 66.4
Tyvyt® |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 393.4 | 293.3 | 418.1
Tyvyt® | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 0.0 | 0.0 | 0.0
Tyvyt® | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 393.4 | 293.3 | 418.1
Alimta® | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 72.9 | 543.7 | 1,233.9
Alimta® | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 144.6 | 384.0 | 827.5
Other oncology | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 283.9 | 169.7 | 120.1
Other oncology | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 329.0 | 254.1 | 210.7
Immunology | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 2,057.9 | 1,892.8 | 1,881.8
Immunology | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 1,739.6 | 1,451.8 | 1,479.0
Taltz® | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 1,831.6 | 1,724.6 | 1,542.4
Taltz® | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 928.0 | 757.4 | 670.4
Olumiant |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 922.6 | 830.5 | 1,115.1
Olumiant | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 225.5 | 148.2 | 324.1
Olumiant | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 697.2 | 682.3 | 791.0
Other immunology | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 0.8 | 20.0 | 15.3
Other immunology | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 114.4 | 12.1 | 17.6
Neuroscience | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 696.0 | 612.4 | 614.8
Neuroscience | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 2,182.5 | 933.8 | 1,283.7
Zyprexa® | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 79.4 | 30.4 | 39.6
Zyprexa® | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 1,615.4 | 306.5 | 390.7
Emgality® | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 482.2 | 462.8 | 434.5
Emgality® | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 196.0 | 188.1 | 142.7
Other neuroscience | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 134.4 | 119.2 | 140.7
Other neuroscience | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 371.1 | 439.2 | 750.3
Other | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 459.3 | 2,555.7 | 2,566.4
Other | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 662.9 | 964.0 | 1,563.5
Forteo® | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 335.5 | 367.3 | 441.6
Forteo® | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 197.7 | 245.8 | 360.3
Cialis® | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 26.1 | 35.2 | 10.6
Cialis® | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 355.3 | 552.1 | 707.9
COVID-19 antibodies |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue |  | 2,020.0 | 2,240.0
COVID-19 antibodies | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 0.0 | 2,008.9 | 1,978.0
COVID-19 antibodies | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 0.0 | 14.7 | 261.4
Other | U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | 97.7 | 144.2 | 136.1
Other | Outside U.S. |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Revenue | $ 109.9 | $ 151.3 | $ 233.9

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