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Revenue - Disaggregation of Revenue by Product (Details) - USD ($) $ in Millions | 3 Months Ended | 6 Months Ended
--- | --- | ---
Jun. 30, 2024 | Jun. 30, 2023 | Jun. 30, 2024 | Jun. 30, 2023
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | $ 11,302.8 | $ 8,312.1 | $ 20,070.8 | $ 15,272.1
U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 7,835.2 | 5,531.4 | 13,529.6 | 9,967.6
Outside U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 3,467.5 | 2,780.7 | 6,541.2 | 5,304.6
Cardiometabolic Health |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 7,514.6 | 5,010.9 | 13,007.6 | 9,201.3
Cardiometabolic Health | U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 5,716.1 | 3,781.4 | 9,806.1 | 6,856.4
Cardiometabolic Health | Outside U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 1,798.5 | 1,229.5 | 3,201.6 | 2,344.9
Mounjaro® |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 3,090.8 | 979.7 | 4,897.4 | 1,548.2
Mounjaro® | U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 2,413.7 | 915.7 | 3,934.0 | 1,452.2
Mounjaro® | Outside U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 677.2 | 64.0 | 963.4 | 96.0
Trulicity® |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 1,245.6 | 1,812.5 | 2,701.9 | 3,789.6
Trulicity® | U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 876.7 | 1,371.3 | 1,958.6 | 2,918.7
Trulicity® | Outside U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 368.9 | 441.2 | 743.3 | 871.0
Zepbound® |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 1,243.2 | 0.0 | 1,760.6 | 0.0
Zepbound® | U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 1,243.2 | 0.0 | 1,760.6 | 0.0
Zepbound® | Outside U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 0.0 | 0.0 | 0.0 | 0.0
Jardiance |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 769.6 | 668.3 | 1,456.1 | 1,245.8
Jardiance | U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 428.9 | 386.1 | 797.1 | 715.6
Jardiance | Outside U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 340.7 | 282.2 | 659.0 | 530.2
Humalog® |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 631.6 | 440.4 | 1,170.3 | 901.4
Humalog® | U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 434.7 | 229.8 | 773.0 | 501.4
Humalog® | Outside U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 196.9 | 210.6 | 397.3 | 400.0
Humulin® |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 223.6 | 205.3 | 429.8 | 457.3
Humulin® | U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 169.3 | 144.3 | 322.4 | 343.1
Humulin® | Outside U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 54.2 | 61.0 | 107.4 | 114.2
Basaglar® |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 180.8 | 154.2 | 338.3 | 363.5
Basaglar® | U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 105.2 | 83.0 | 188.4 | 218.4
Basaglar® | Outside U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 75.6 | 71.2 | 149.9 | 145.2
Baqsimi |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 12.4 | 613.9 | 11.5 | 645.4
Baqsimi | U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 3.3 | 606.2 | (6.9) | 629.3
Baqsimi | Outside U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 9.0 | 7.7 | 18.3 | 16.1
Other cardiometabolic health |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 117.0 | 136.6 | 241.7 | 250.1
Other cardiometabolic health | U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 41.1 | 45.0 | 78.9 | 77.7
Other cardiometabolic health | Outside U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 76.0 | 91.6 | 163.0 | 172.2
Oncology |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 2,158.7 | 1,671.0 | 3,968.7 | 3,027.0
Oncology | U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 1,275.2 | 935.0 | 2,273.5 | 1,688.4
Oncology | Outside U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 883.5 | 736.0 | 1,695.1 | 1,338.6
Verzenio® |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 1,331.9 | 926.8 | 2,382.2 | 1,677.7
Verzenio® | U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 861.4 | 588.6 | 1,499.6 | 1,049.6
Verzenio® | Outside U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 470.5 | 338.2 | 882.6 | 628.0
Cyramza® |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 248.9 | 260.3 | 478.7 | 497.0
Cyramza® | U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 116.1 | 115.0 | 223.3 | 215.6
Cyramza® | Outside U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 132.8 | 145.3 | 255.4 | 281.4
Erbitux® |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 155.8 | 162.5 | 300.4 | 292.4
Erbitux® | U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 142.9 | 145.5 | 275.0 | 264.2
Erbitux® | Outside U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 13.0 | 17.0 | 25.4 | 28.1
Tyvyt® |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 123.0 | 103.6 | 239.7 | 164.6
Tyvyt® | U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 0.0 | 0.0 | 0.0 | 0.0
Tyvyt® | Outside U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 123.0 | 103.6 | 239.7 | 164.6
Other oncology |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 299.1 | 217.8 | 567.7 | 395.3
Other oncology | U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 154.8 | 85.9 | 275.6 | 159.0
Other oncology | Outside U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 144.2 | 131.9 | 292.0 | 236.5
Immunology |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 1,082.4 | 928.5 | 1,916.3 | 1,706.3
Immunology | U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 599.8 | 523.1 | 996.9 | 877.6
Immunology | Outside U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 482.6 | 405.4 | 919.4 | 828.6
Taltz® |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 824.7 | 703.9 | 1,428.8 | 1,230.8
Taltz® | U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 539.4 | 472.3 | 886.4 | 784.5
Taltz® | Outside U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 285.3 | 231.6 | 542.3 | 446.3
Olumiant® |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 227.7 | 218.9 | 445.1 | 447.8
Olumiant® | U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 44.5 | 50.8 | 90.9 | 93.1
Olumiant® | Outside U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 183.2 | 168.1 | 354.2 | 354.6
Other immunology |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 30.0 | 5.7 | 42.4 | 27.7
Other immunology | U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 15.9 | 0.0 | 19.6 | 0.0
Other immunology | Outside U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 14.1 | 5.7 | 22.9 | 27.7
Neuroscience |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 339.5 | 387.2 | 728.6 | 747.7
Neuroscience | U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 191.9 | 160.9 | 355.1 | 305.4
Neuroscience | Outside U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 147.6 | 226.3 | 373.5 | 442.3
Emgality® |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 192.0 | 169.3 | 417.8 | 323.6
Emgality® | U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 137.6 | 118.8 | 262.7 | 227.5
Emgality® | Outside U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 54.4 | 50.5 | 155.1 | 96.1
Other neuroscience |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 147.5 | 217.9 | 310.8 | 424.1
Other neuroscience | U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 54.3 | 42.1 | 92.4 | 77.9
Other neuroscience | Outside U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 93.2 | 175.8 | 218.4 | 346.2
Other |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 207.6 | 314.6 | 449.6 | 589.9
Other | U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 52.2 | 131.0 | 98.0 | 239.8
Other | Outside U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 155.4 | 183.5 | 351.6 | 350.1
Cialis® |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 87.7 | 115.6 | 227.1 | 215.9
Cialis® | U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 7.5 | 9.2 | 13.4 | 16.8
Cialis® | Outside U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 80.2 | 106.4 | 213.7 | 199.1
Forteo® |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 69.9 | 148.0 | 131.2 | 270.3
Forteo® | U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 31.5 | 97.4 | 53.2 | 168.0
Forteo® | Outside U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 38.5 | 50.6 | 78.0 | 102.3
Other |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 50.0 | 51.0 | 91.3 | 103.7
Other | U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | 13.2 | 24.4 | 31.4 | 55.0
Other | Outside U.S. |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenue | $ 36.7 | $ 26.5 | $ 59.9 | $ 48.7

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