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v3.25.0.1

Consolidated Statements of Cash Flows - USD ($) $ in Millions | 12 Months Ended
--- | ---
Dec. 31, 2024 | Dec. 31, 2023 | Dec. 31, 2022
Cash Flows from Operating Activities |  |  |
Net income | $ 10,590.0 | $ 5,240.4 | $ 6,244.8
Adjustments to Reconcile Net Income to Cash Flows from Operating Activities: |  |  |
Depreciation and amortization | 1,766.6 | 1,527.3 | 1,522.5
Change in deferred income taxes | (2,683.1) | (2,341.0) | (2,185.2)
Stock-based compensation expense | 645.6 | 628.5 | 371.1
Investment (gains) losses, net | 49.8 | 23.5 | 420.0
Gains on sale of product rights | (223.8) | (1,878.9) | (156.5)
Acquired in-process research and development | 3,280.4 | 3,799.8 | 908.5
Other operating activities, net | 777.4 | 295.5 | 461.3
Other changes in operating assets and liabilities, net of acquisitions and divestitures: |  |  |
Receivables—(increase) decrease | (2,155.2) | (2,451.0) | (299.6)
Inventories—(increase) decrease | (2,507.4) | (1,425.0) | (599.7)
Prepaid expenses and other assets—(increase) decrease | (3,331.2) | (3,453.4) | (793.5)
Accounts payable and other liabilities—increase (decrease) | 2,608.8 | 4,274.4 | 1,692.0
Net Cash Provided by Operating Activities | 8,817.9 | 4,240.1 | 7,585.7
Cash Flows from Investing Activities |  |  |
Purchases of property and equipment | (5,057.8) | (3,447.6) | (1,854.3)
Proceeds from sales and maturities of short-term investments | 148.9 | 192.2 | 121.4
Purchases of short-term investments | (98.5) | (98.2) | (107.4)
Proceeds from sales of and distributions from noncurrent investments | 373.6 | 508.1 | 342.2
Purchases of noncurrent investments | (677.3) | (730.8) | (600.2)
Proceeds from sale of product rights | 601.3 | 1,604.3 | 95.8
Purchases of in-process research and development | (3,345.8) | (3,944.5) | (1,131.0)
Cash paid for acquisitions, net of cash acquired | (947.7) | (1,044.3) | (327.2)
Other investing activities, net | (298.2) | (191.9) | (302.2)
Net Cash Used for Investing Activities | (9,301.5) | (7,152.7) | (3,762.9)
Cash Flows from Financing Activities |  |  |
Dividends paid | (4,680.4) | (4,069.3) | (3,535.8)
Net change in short-term borrowings | (1,851.8) | 4,691.4 | 1,498.0
Proceeds from issuance of long-term debt | 11,417.1 | 3,958.5 | 0.0
Repayments of long-term debt | (664.2) | 0.0 | (1,560.0)
Purchases of common stock | (2,500.0) | (750.0) | (1,500.0)
Other financing activities, net | (490.6) | (335.0) | (308.9)
Net Cash Provided by (Used for) Financing Activities | 1,230.1 | 3,495.6 | (5,406.7)
Effect of exchange rate changes on cash and cash equivalents | (296.7) | 168.6 | (167.6)
Net increase (decrease) in cash and cash equivalents | 449.8 | 751.6 | (1,751.5)
Cash and cash equivalents at beginning of year | 2,818.6 | 2,067.0 | 3,818.5
Cash and Cash Equivalents at End of Year | $ 3,268.4 | $ 2,818.6 | $ 2,067.0

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