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Consolidated Condensed Statements of Operations (Unaudited) - USD ($)
shares in Thousands, $ in Millions
 3 Months Ended
Mar. 31, 2025
Mar. 31, 2024
Income Statement [Abstract]    
Revenue (Note 2) $ 12,728.5 $ 8,768.0
Costs, expenses, and other:    
Cost of sales 2,224.2 1,673.5
Research and development 2,733.7 2,522.8
Marketing, selling, and administrative 2,468.8 1,952.2
Acquired in-process research and development (Note 3) 1,571.7 110.5
Asset impairment, restructuring, and other special charges 35.0 0.0
Other–net, (income) expense (Note 11) 239.0 (27.1)
Costs, expenses, and other 9,272.4 6,231.9
Income before income taxes 3,456.1 2,536.1
Income taxes (Note 7) 696.8 293.2
Net income $ 2,759.3 $ 2,242.9
Earnings per share:    
Basic (in dollars per share) $ 3.07 $ 2.49
Diluted (in dollars per share) $ 3.06 $ 2.48
Shares used in calculation of earnings per share:    
Basic (in shares) 898,700 900,800
Diluted (in shares) 900,600 903,800