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Segment Information (Tables)
3 Months Ended
Mar. 31, 2025
Segment Reporting [Abstract]  
Schedule of Segment Reporting Information, by Segment
The following table summarizes our segment revenue, significant segment expenses, and segment profit:
Three Months Ended March 31,
20252024
Revenue$12,728.5 $8,768.0 
Less:
Cost of sales2,224.2 1,673.5 
Early-stage research and development(1)
990.0 852.1 
Late-stage research and development(1)
1,743.7 1,670.7 
Marketing, selling, and administrative2,468.8 1,952.2 
Acquired in-process research and development1,571.7 110.5 
Other segment items(2)
970.8 266.1 
Net income$2,759.3 $2,242.9 
(1) Early-stage research and development primarily includes costs incurred from discovery through Phase 2 clinical trials. Late-stage research and development primarily includes costs incurred from Phase 3 clinical trials.
(2) Other segment items primarily include income taxes and asset impairment, restructuring, and other special charges.
The following tables summarize additional segment information:
Three Months Ended March 31,
20252024
Interest expense$243.7 $179.6 
Interest income48.3 45.8 
Depreciation and amortization462.8 400.6 
Asset impairment, restructuring, and other special charges35.0 — 
Earnings (loss) in equity method investments
(58.7)13.7 
Income taxes696.8 293.2 
Expenditures for long-lived assets(1)
1,516.6 1,059.6 
(1) Includes expenditures for property and equipment and computer software costs.
March 31, 2025December 31, 2024
Total assets$89,388.8 $78,714.9 
Equity method investments
1,148.6 1,142.7