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Segment Information (Details)
$ in Millions
 3 Months Ended 12 Months Ended
Mar. 31, 2025
USD ($)
segment
Mar. 31, 2024
USD ($)
Dec. 31, 2024
USD ($)
Segment Reporting [Abstract]      
Number of reportable segments | segment 1    
Financial Information Regularly Reviewed by the CODM      
Revenue $ 12,728.5 $ 8,768.0  
Less:      
Cost of sales 2,224.2 1,673.5  
Research and development 2,733.7 2,522.8  
Marketing, selling, and administrative 2,468.8 1,952.2  
Acquired in-process research and development 1,571.7 110.5  
Net income 2,759.3 2,242.9  
Additional Segment Information      
Interest expense 243.7 179.6  
Interest income 48.3 45.8  
Depreciation and amortization 462.8 400.6  
Income taxes 696.8 293.2  
Total assets 89,388.8   $ 78,714.9
Reportable Segment      
Financial Information Regularly Reviewed by the CODM      
Revenue 12,728.5 8,768.0  
Less:      
Cost of sales 2,224.2 1,673.5  
Marketing, selling, and administrative 2,468.8 1,952.2  
Acquired in-process research and development 1,571.7 110.5  
Other segment items 970.8 266.1  
Net income 2,759.3 2,242.9  
Additional Segment Information      
Interest expense 243.7 179.6  
Interest income 48.3 45.8  
Depreciation and amortization 462.8 400.6  
Asset impairment, restructuring, and other special charges 35.0 0.0  
Earnings (loss) in equity method investments (58.7) 13.7  
Income taxes 696.8 293.2  
Expenditures for long-lived assets 1,516.6 1,059.6  
Total assets 89,388.8   78,714.9
Equity method investments 1,148.6   $ 1,142.7
Early-stage | Reportable Segment      
Less:      
Research and development 990.0 852.1  
Late-stage | Reportable Segment      
Less:      
Research and development $ 1,743.7 $ 1,670.7