<SEC-DOCUMENT>0001415889-25-002113.txt : 20250127
<SEC-HEADER>0001415889-25-002113.hdr.sgml : 20250127
<ACCEPTANCE-DATETIME>20250127155431
ACCESSION NUMBER:		0001415889-25-002113
CONFORMED SUBMISSION TYPE:	SCHEDULE 13G/A
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20250127

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ELI LILLY & Co
		CENTRAL INDEX KEY:			0000059478
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		IRS NUMBER:				350470950
		STATE OF INCORPORATION:			IN
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13G/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-17885
		FILM NUMBER:		25558767

	BUSINESS ADDRESS:	
		STREET 1:		LILLY CORPORATE CTR
		STREET 2:		DROP CODE 1094
		CITY:			INDIANAPOLIS
		STATE:			IN
		ZIP:			46285
		BUSINESS PHONE:		3172762000

	MAIL ADDRESS:	
		STREET 1:		LILLY CORPORATE CENTER
		STREET 2:		DROP CODE 1094
		CITY:			INDIANAPOLIS
		STATE:			IN
		ZIP:			46285

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	LILLY ELI & CO
		DATE OF NAME CHANGE:	19941024

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			LILLY ENDOWMENT INC
		CENTRAL INDEX KEY:			0000316011
		ORGANIZATION NAME:           	
		IRS NUMBER:				350868122
		STATE OF INCORPORATION:			IN
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13G/A

	BUSINESS ADDRESS:	
		STREET 1:		2801 NORTH MERIDIAN STREET
		CITY:			INDIANANAPOLIS
		STATE:			IN
		ZIP:			46208
		BUSINESS PHONE:		3179245471

	MAIL ADDRESS:	
		STREET 1:		2801 NORTH MERIDIAN ST
		CITY:			INDIANAPOLIS
		STATE:			IN
		ZIP:			46208
</SEC-HEADER>
<DOCUMENT>
<TYPE>SCHEDULE 13G/A
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/schedule13g" xmlns:com="http://www.sec.gov/edgar/common">
  <headerData>
    <submissionType>SCHEDULE 13G/A</submissionType>
		<previousAccessionNumber>0000911916-94-000024</previousAccessionNumber>
	    <filerInfo>
      <filer>
        <filerCredentials>
          <cik>0000316011</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>





    </filerInfo>
  </headerData>

  <formData>
    <coverPageHeader>
		<amendmentNo>15</amendmentNo>
	      <securitiesClassTitle>Common Stock, Without Par Value</securitiesClassTitle>
      <eventDateRequiresFilingThisStatement>12/31/2024</eventDateRequiresFilingThisStatement>
      <issuerInfo>
        <issuerCik>0000059478</issuerCik>        <issuerName>ELI LILLY AND CO</issuerName>        <issuerCusip>532457108</issuerCusip>
        <issuerPrincipalExecutiveOfficeAddress>
          <com:street1>LILLY CORPORATE CTR</com:street1>
          <com:street2>DROP CODE 1094</com:street2>          <com:city>INDIANAPOLIS</com:city>
          <com:stateOrCountry>IN</com:stateOrCountry>
          <com:zipCode>46285</com:zipCode>
        </issuerPrincipalExecutiveOfficeAddress>
      </issuerInfo>

	        <designateRulesPursuantThisScheduleFiled>
	           <designateRulePursuantThisScheduleFiled>Rule 13d-1(d)</designateRulePursuantThisScheduleFiled>
						      </designateRulesPursuantThisScheduleFiled>

    </coverPageHeader>

	    <coverPageHeaderReportingPersonDetails>




    <reportingPersonName>LILLY ENDOWMENT INC</reportingPersonName>



		 <citizenshipOrOrganization>IN</citizenshipOrOrganization>

      <reportingPersonBeneficiallyOwnedNumberOfShares>
                <soleVotingPower>96891978.00</soleVotingPower>
                          <sharedVotingPower>0.00</sharedVotingPower>
                          <soleDispositivePower>96891978.00</soleDispositivePower>
                         <sharedDispositivePower>0.00</sharedDispositivePower>
             </reportingPersonBeneficiallyOwnedNumberOfShares>

              <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>96891978.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>


     	    <classPercent>10.2</classPercent>









	        <typeOfReportingPerson>CO</typeOfReportingPerson>





	  <comments>The percentage of class represented is based on 949,315,694 shares of common stock outstanding as of October 25, 2024 (the most recent date for which such information is publicly available), as reported on the Issuer's Form 10-Q for the period ended September 30, 2024.

This information is provided as of December 31, 2024.</comments>

    </coverPageHeaderReportingPersonDetails>

    <items>
      <item1>
        <issuerName>ELI LILLY AND CO</issuerName>
        <issuerPrincipalExecutiveOfficeAddress>LILLY CORPORATE CTR, DROP CODE 1094, INDIANAPOLIS, IN, 46285.</issuerPrincipalExecutiveOfficeAddress>
      </item1>

      <item2>
        <filingPersonName>This statement is filed by Lilly Endowment Inc., a not for profit corporation organized under the laws of the State of Indiana.  Lilly Endowment Inc. is an organization described in Section 501(c)(3) of the Internal Revenue Code of 1986 and is a private foundation under Section 509(a) of the Code.

</filingPersonName>        <principalBusinessOfficeOrResidenceAddress>The address of the principal business office of Lilly Endowment Inc. is 2801 North Meridian Street, Indianapolis, IN 46208.</principalBusinessOfficeOrResidenceAddress>        <citizenship>Indiana</citizenship>      </item2>

        <item3>
		        <notApplicableFlag>Y</notApplicableFlag>

      </item3>



    <item4>
    <amountBeneficiallyOwned>96,891,978 shares as of December 31, 2024 - None of such shares are deemed to be beneficially owned by reason of the possession of Lilly Endowment Inc. of a right to acquire such shares.</amountBeneficiallyOwned>    <classPercent>10.2%</classPercent>
      <numberOfSharesPersonHas>
        <solePowerOrDirectToVote>96,891,978 shares</solePowerOrDirectToVote>
        <sharedPowerOrDirectToVote>0</sharedPowerOrDirectToVote>
        <solePowerOrDirectToDispose>96,891,978 shares</solePowerOrDirectToDispose>
        <sharedPowerOrDirectToDispose>0</sharedPowerOrDirectToDispose>
      </numberOfSharesPersonHas>
    </item4>


        <item5>
	          <notApplicableFlag>Y</notApplicableFlag>


    </item5>


        <item6>
	  	  <notApplicableFlag>Y</notApplicableFlag>
		        </item6>


        <item7>
	  	  <notApplicableFlag>Y</notApplicableFlag>


    </item7>


          <item8>
                <notApplicableFlag>Y</notApplicableFlag>

              </item8>


            <item9>
                <notApplicableFlag>Y</notApplicableFlag>
                      </item9>


      <item10>
                    <notApplicableFlag>Y</notApplicableFlag>

      </item10>
    </items>


	    <signatureInformation>
      <reportingPersonName>LILLY ENDOWMENT INC</reportingPersonName>

      <signatureDetails>
        <signature>Diane M. Stenson</signature>
        <title>Vice President and Treasurer</title>
        <date>01/27/2025</date>
      </signatureDetails>

    </signatureInformation>



  </formData>

    </edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
