<SEC-DOCUMENT>0000059478-25-000243.txt : 20251003
<SEC-HEADER>0000059478-25-000243.hdr.sgml : 20251003
<ACCEPTANCE-DATETIME>20251003161639
ACCESSION NUMBER:		0000059478-25-000243
CONFORMED SUBMISSION TYPE:	SCHEDULE 13G/A
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20251003
DATE AS OF CHANGE:		20251003

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Immunocore Holdings plc
		CENTRAL INDEX KEY:			0001671927
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		ORGANIZATION NAME:           	03 Life Sciences
		EIN:				000000000
		STATE OF INCORPORATION:			X0
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13G/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-92246
		FILM NUMBER:		251374079

	BUSINESS ADDRESS:	
		STREET 1:		90 PARK DRIVE
		STREET 2:		MILTON PARK, ABINGDON
		CITY:			OXFORDSHIRE
		STATE:			X0
		ZIP:			OX14 4RY
		BUSINESS PHONE:		01235 5430281

	MAIL ADDRESS:	
		STREET 1:		90 PARK DRIVE
		STREET 2:		MILTON PARK, ABINGDON
		CITY:			OXFORDSHIRE
		STATE:			X0
		ZIP:			OX14 4RY

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Immunocore Ltd
		DATE OF NAME CHANGE:	20160412

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ELI LILLY & Co
		CENTRAL INDEX KEY:			0000059478
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		EIN:				350470950
		STATE OF INCORPORATION:			IN
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13G/A

	BUSINESS ADDRESS:	
		STREET 1:		LILLY CORPORATE CTR
		STREET 2:		DROP CODE 1094
		CITY:			INDIANAPOLIS
		STATE:			IN
		ZIP:			46285
		BUSINESS PHONE:		3172762000

	MAIL ADDRESS:	
		STREET 1:		LILLY CORPORATE CENTER
		STREET 2:		DROP CODE 1094
		CITY:			INDIANAPOLIS
		STATE:			IN
		ZIP:			46285

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	LILLY ELI & CO
		DATE OF NAME CHANGE:	19941024
</SEC-HEADER>
<DOCUMENT>
<TYPE>SCHEDULE 13G/A
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/schedule13g" xmlns:com="http://www.sec.gov/edgar/common">
  <headerData>
    <submissionType>SCHEDULE 13G/A</submissionType>
    <previousAccessionNumber>0001193125-22-034420</previousAccessionNumber>
    <filerInfo>
      <filer>
        <filerCredentials>
          <cik>0000059478</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>



    </filerInfo>
  </headerData>
  <formData>
    <coverPageHeader>
      <amendmentNo>1</amendmentNo>
      <securitiesClassTitle>Ordinary Shares</securitiesClassTitle>
      <eventDateRequiresFilingThisStatement>09/30/2025</eventDateRequiresFilingThisStatement>
      <issuerInfo>
        <issuerCik>0001671927</issuerCik>
        <issuerName>Immunocore Holdings plc</issuerName>
        <issuerCusip>54258D105</issuerCusip>
        <issuerPrincipalExecutiveOfficeAddress>
          <com:street1>90 PARK DRIVE</com:street1>
          <com:street2>MILTON PARK</com:street2>
          <com:city>ABINGDON, OXFORDSHIRE</com:city>
          <com:stateOrCountry>X0</com:stateOrCountry>
          <com:zipCode>OX14 4RY</com:zipCode>
        </issuerPrincipalExecutiveOfficeAddress>
      </issuerInfo>
      <designateRulesPursuantThisScheduleFiled>
        <designateRulePursuantThisScheduleFiled>Rule 13d-1(d)</designateRulePursuantThisScheduleFiled>
      </designateRulesPursuantThisScheduleFiled>
    </coverPageHeader>
    <coverPageHeaderReportingPersonDetails>

      <reportingPersonName>ELI LILLY &amp; Co</reportingPersonName>
      <citizenshipOrOrganization>IN</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>0.00</soleVotingPower>
        <sharedVotingPower>0.00</sharedVotingPower>
        <soleDispositivePower>0.00</soleDispositivePower>
        <sharedDispositivePower>0.00</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>0.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <classPercent>0.0</classPercent>
      <typeOfReportingPerson>CO</typeOfReportingPerson>
    </coverPageHeaderReportingPersonDetails>
    <coverPageHeaderReportingPersonDetails>

      <reportingPersonName>ELI LILLY S.A.</reportingPersonName>
      <citizenshipOrOrganization>V8</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>0.00</soleVotingPower>
        <sharedVotingPower>0.00</sharedVotingPower>
        <soleDispositivePower>0.00</soleDispositivePower>
        <sharedDispositivePower>0.00</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>0.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <classPercent>0.0</classPercent>
      <typeOfReportingPerson>CO</typeOfReportingPerson>
    </coverPageHeaderReportingPersonDetails>
    <items>
      <item1>
        <issuerName>Immunocore Holdings plc</issuerName>
        <issuerPrincipalExecutiveOfficeAddress>90 PARK DRIVE, MILTON PARK, ABINGDON, OXFORDSHIRE, UNITED KINGDOM, OX14 4RY.</issuerPrincipalExecutiveOfficeAddress>
      </item1>
      <item2>
        <filingPersonName>Eli Lilly S.A.
Eli Lilly and Company</filingPersonName>
        <principalBusinessOfficeOrResidenceAddress>c/o Lilly Corporate Center
Indianapolis, Indiana 46285</principalBusinessOfficeOrResidenceAddress>
        <citizenship>Eli Lilly S.A. Switzerland societe anonyme
Eli Lilly and Company Indiana corporation</citizenship>
      </item2>
      <item3>
        <notApplicableFlag>Y</notApplicableFlag>
      </item3>
      <item4>
        <amountBeneficiallyOwned>See Item 9 of Cover Sheet.</amountBeneficiallyOwned>
        <classPercent>See Item 11 of Cover Sheet.</classPercent>
        <numberOfSharesPersonHas>
          <solePowerOrDirectToVote>See Item 5 of Cover Sheet.
</solePowerOrDirectToVote>
          <sharedPowerOrDirectToVote>See Item 6 of Cover Sheet.
</sharedPowerOrDirectToVote>
          <solePowerOrDirectToDispose>See Item 7 of Cover Sheet.
</solePowerOrDirectToDispose>
          <sharedPowerOrDirectToDispose>See Item 8 of Cover Sheet.
</sharedPowerOrDirectToDispose>
        </numberOfSharesPersonHas>
      </item4>
      <item5>
        <classOwnership5PercentOrLess>Y</classOwnership5PercentOrLess>
      </item5>
      <item6>
        <notApplicableFlag>Y</notApplicableFlag>
      </item6>
      <item7>
        <notApplicableFlag>Y</notApplicableFlag>
      </item7>
      <item8>
        <notApplicableFlag>Y</notApplicableFlag>
      </item8>
      <item9>
        <notApplicableFlag>Y</notApplicableFlag>
      </item9>
      <item10>
        <notApplicableFlag>Y</notApplicableFlag>
      </item10>
    </items>
    <signatureInformation>
      <reportingPersonName>ELI LILLY &amp; Co</reportingPersonName>
      <signatureDetails>
        <signature>/s/ Christopher Anderson</signature>
        <title>Attorney-in-Fact</title>
        <date>10/03/2025</date>
      </signatureDetails>
    </signatureInformation>
    <signatureInformation>
      <reportingPersonName>ELI LILLY S.A.</reportingPersonName>
      <signatureDetails>
        <signature>/s/ Christopher Anderson</signature>
        <title>Attorney-in-Fact</title>
        <date>10/03/2025</date>
      </signatureDetails>
    </signatureInformation>
    <signatureComments>This Schedule 13G/A was executed pursuant to a power of attorney for Eli Lilly and Company previously
filed with the Securities and Exchange Commission, and hereby incorporated by reference herein. The
power of attorney was filed as Exhibit 99.3 to a filing on Schedule 13G for the Issuer on February 10,
2022.

This Schedule 13G/A was executed pursuant to a power of attorney for Eli Lilly S.A. previously filed with
the Securities and Exchange Commission, and hereby incorporated by reference herein. The power of
attorney was filed as Exhibit 99.2 to a filing on Schedule 13G for the Issuer on February 10, 2022.</signatureComments>
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</DOCUMENT>
</SEC-DOCUMENT>
