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Intangible assets and goodwill - Goodwill (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 29, 2024
Dec. 31, 2023
Goodwill [Roll Forward]    
Goodwill beginning of period $ 36,558 $ 36,047
Goodwill, related to acquisitions 8,209 0
Goodwill, related to divestitures (56) 0
Currency translation/other (511) 511
Goodwill end of period 44,200 36,558
Innovative Medicine    
Goodwill [Roll Forward]    
Goodwill beginning of period 10,407 10,184
Goodwill, related to acquisitions 640 0
Goodwill, related to divestitures 0 0
Currency translation/other (355) 223
Goodwill end of period 10,692 10,407
MedTech    
Goodwill [Roll Forward]    
Goodwill beginning of period 26,151 25,863
Goodwill, related to acquisitions 7,569 0
Goodwill, related to divestitures (56) 0
Currency translation/other (156) 288
Goodwill end of period $ 33,508 $ 26,151