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Segment and Geographic Information - Summary of Reconciliation of Segment Financial Information to Loss from Operations (Detail) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2025
Sep. 30, 2024
Sep. 30, 2025
Sep. 30, 2024
Segment Reporting Information [Line Items]        
Income from operations $ 393,256 $ 113,140 $ 838,621 $ 299,360
Total stock-based compensation expense 172,318 142,425 487,628 409,840
Reconciling items        
Segment Reporting Information [Line Items]        
Income from operations 393,256 113,140 838,621 299,360
Research and development expenses 109,142 86,840 315,172 248,844
General and administrative expenses 103,370 90,819 316,758 266,136
Total stock-based compensation expense 172,318 142,425 487,628 409,840
Operating Segments        
Segment Reporting Information [Line Items]        
Contribution $ 778,086 $ 433,224 $ 1,958,179 $ 1,224,180