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Segment Information (Tables)
9 Months Ended
Sep. 30, 2025
Segment Reporting [Abstract]  
Schedule of worldwide net revenues
The following table details AbbVie’s worldwide net revenues:
Three months ended
September 30,
Nine months ended
September 30,
(in millions)2025202420252024
Immunology
SkyriziUnited States$4,085 $2,778 $10,847 $6,774 
International623 427 1,709 1,166 
Total$4,708 $3,205 $12,556 $7,940 
RinvoqUnited States$1,559 $1,170 $4,231 $2,912 
International625 444 1,699 1,225 
Total$2,184 $1,614 $5,930 $4,137 
HumiraUnited States$619 $1,765 $2,165 $5,896 
International374 462 1,129 1,415 
Total$993 $2,227 $3,294 $7,311 
Neuroscience
VraylarUnited States$931 $873 $2,592 $2,338 
International
Total$934 $875 $2,599 $2,343 
Botox TherapeuticUnited States$825 $708 $2,323 $1,988 
International160 140 456 422 
Total$985 $848 $2,779 $2,410 
UbrelvyUnited States$344 $261 $907 $685 
International10 25 18 
Total$354 $269 $932 $703 
QuliptaUnited States$252 $168 $661 $442 
International36 87 15 
Total$288 $176 $748 $457 
VyalevUnited States$53 $— $81 $— 
International85 28 218 55 
Total$138 $28 $299 $55 
DuodopaUnited States$16 $24 $56 $72 
International80 87 233 267 
Total$96 $111 $289 $339 
Other NeuroscienceUnited States$42 $54 $148 $172 
International12 11 
Total$46 $56 $160 $183 
Three months ended
September 30,
Nine months ended
September 30,
(in millions)2025202420252024
Oncology
ImbruvicaUnited States$507 $618 $1,579 $1,823 
Collaboration revenues199 210 619 676 
Total$706 $828 $2,198 $2,499 
VenclextaUnited States$341 $340 $974 $921 
International385 337 1,108 1,007 
Total$726 $677 $2,082 $1,928 
Elahere
United States
$150 $139 $453 $331 
International
20 — 55 — 
Total$170 $139 $508 $331 
Epkinly
Collaboration revenues
$44 $31 $129 $82 
International25 12 61 24 
Total$69 $43 $190 $106 
Other OncologyUnited States$11 $— $13 $— 
Aesthetics
Botox CosmeticUnited States$379 $414 $1,084 $1,253 
International258 257 801 780 
Total$637 $671 $1,885 $2,033 
Juvederm CollectionUnited States$98 $105 $278 $349 
International155 153 466 549 
Total$253 $258 $744 $898 
Other AestheticsUnited States$265 $272 $817 $828 
International38 38 128 119 
Total$303 $310 $945 $947 
Eye Care
OzurdexUnited States$32 $33 $92 $102 
International85 86 273 272 
Total$117 $119 $365 $374 
Lumigan/GanfortUnited States$42 $58 $142 $129 
International55 58 164 181 
Total$97 $116 $306 $310 
Alphagan/CombiganUnited States$$26 $35 $54 
International38 36 108 116 
Total$47 $62 $143 $170 
Other Eye CareUnited States$138 $123 $399 $421 
International110 105 316 321 
Total$248 $228 $715 $742 
Other Key Products
MavyretUnited States$146 $147 $472 $458 
International166 155 521 562 
Total$312 $302 $993 $1,020 
CreonUnited States$368 $338 $1,127 $995 
Linzess/ConstellaUnited States$315 $225 $701 $693 
International11 31 28 
Total$326 $234 $732 $721 
All other$660 $726 $2,010 $2,280 
Total net revenues$15,776 $14,460 $44,542 $41,232