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Licensing, Acquisitions and Other Arrangements (Details) - USD ($)
$ in Millions
1 Months Ended 3 Months Ended 9 Months Ended
Jun. 30, 2024
Sep. 30, 2025
Jun. 30, 2025
Sep. 30, 2024
Sep. 30, 2025
Sep. 30, 2024
Collaborative and license agreements            
Cash outflows related to acquisitions and investments         $ (4,076) $ (1,232)
Acquired IPR&D and milestones   $ 2,680   $ 82 3,751 1,183
Collaborative arrangement            
Collaborative and license agreements            
Research and development milestone expenses   65   0 185 95
Ichnos Glenmark Innovation, Inc.            
Collaborative and license agreements            
Acquired IPR&D and milestones   700        
Ichnos Glenmark Innovation, Inc. | Collaborative arrangement            
Collaborative and license agreements            
Potential Payments under Agreement Certain Milestones   1,200     1,200  
Capstan Therapeutics, Inc.            
Collaborative and license agreements            
Acquired IPR&D and milestones   1,900        
Cash consideration paid to shareholders   2,100        
Cash-Settled, Post-Closing Expense for Employee Incentive and Compensation Awards   187        
ADARx Pharmaceuticals, Inc.            
Collaborative and license agreements            
Acquired IPR&D and milestones     $ 335      
ADARx Pharmaceuticals, Inc. | Collaborative arrangement            
Collaborative and license agreements            
Potential Payments under Agreement Certain Milestones     7,500      
Option fees and exercise payments     385      
Gubra A/S            
Collaborative and license agreements            
Acquired IPR&D and milestones     350      
Gubra A/S | Collaborative arrangement            
Collaborative and license agreements            
Potential Payments under Agreement Certain Milestones     $ 1,900      
Celsius Therapeutics            
Collaborative and license agreements            
Cash consideration paid to shareholders $ 250          
Other Collaboration Arrangements | Collaborative arrangement            
Collaborative and license agreements            
Acquired IPR&D and milestones   $ 2,615   $ 82 $ 3,566 $ 1,088