<SEC-DOCUMENT>0000899243-19-001171.txt : 20190115
<SEC-HEADER>0000899243-19-001171.hdr.sgml : 20190115
<ACCEPTANCE-DATETIME>20190115092404
ACCESSION NUMBER:		0000899243-19-001171
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20190104
FILED AS OF DATE:		20190115
DATE AS OF CHANGE:		20190115

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Blackstone Holdings II L.P.
		CENTRAL INDEX KEY:			0001484870

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-38537
		FILM NUMBER:		19526295

	BUSINESS ADDRESS:	
		STREET 1:		C/O  THE BLACKSTONE GROUP
		STREET 2:		345 PARK AVENUE
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10154
		BUSINESS PHONE:		212-583-5000

	MAIL ADDRESS:	
		STREET 1:		C/O  THE BLACKSTONE GROUP
		STREET 2:		345 PARK AVENUE
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10154

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Blackstone Clarus III L.L.C.
		CENTRAL INDEX KEY:			0001762202
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-38537
		FILM NUMBER:		19526296

	BUSINESS ADDRESS:	
		STREET 1:		C/O THE BLACKSTONE GROUP L.P.
		STREET 2:		345 PARK AVENUE
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10154
		BUSINESS PHONE:		212-583-5000

	MAIL ADDRESS:	
		STREET 1:		C/O THE BLACKSTONE GROUP L.P.
		STREET 2:		345 PARK AVENUE
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10154

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Blackstone Holdings I/II GP Inc
		CENTRAL INDEX KEY:			0001464695
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-38537
		FILM NUMBER:		19526297

	BUSINESS ADDRESS:	
		STREET 1:		C/O THE BLACKSTONE GROUP
		STREET 2:		345 PARK AVENUE
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10154
		BUSINESS PHONE:		2125835000

	MAIL ADDRESS:	
		STREET 1:		C/O THE BLACKSTONE GROUP
		STREET 2:		345 PARK AVENUE
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10154

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Blackstone Group L.P.
		CENTRAL INDEX KEY:			0001393818
		STANDARD INDUSTRIAL CLASSIFICATION:	INVESTMENT ADVICE [6282]
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-38537
		FILM NUMBER:		19526298

	BUSINESS ADDRESS:	
		STREET 1:		345 PARK AVENUE
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10154
		BUSINESS PHONE:		(212) 583-5000

	MAIL ADDRESS:	
		STREET 1:		345 PARK AVENUE
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10154

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Blackstone Group Management L.L.C.
		CENTRAL INDEX KEY:			0001404071
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-38537
		FILM NUMBER:		19526299

	BUSINESS ADDRESS:	
		STREET 1:		345 PARK AVENUE
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10154
		BUSINESS PHONE:		(212) 583-5000

	MAIL ADDRESS:	
		STREET 1:		345 PARK AVENUE
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10154

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			SCHWARZMAN STEPHEN A
		CENTRAL INDEX KEY:			0001070844

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-38537
		FILM NUMBER:		19526300

	MAIL ADDRESS:	
		STREET 1:		C/O THE BLACKSTONE GROUP
		STREET 2:		345 PARK AVE
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10154

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			AVROBIO, Inc.
		CENTRAL INDEX KEY:			0001681087
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				810710585
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		ONE KENDALL SQUARE
		STREET 2:		BLDG. 300, SUITE 201
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02139
		BUSINESS PHONE:		7819626030

	MAIL ADDRESS:	
		STREET 1:		ONE KENDALL SQUARE
		STREET 2:		BLDG. 300, SUITE 201
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02139

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	AvroBio, Inc.
		DATE OF NAME CHANGE:	20160729
</SEC-HEADER>
<DOCUMENT>
<TYPE>3
<SEQUENCE>1
<FILENAME>doc3.xml
<DESCRIPTION>FORM 3 SUBMISSION
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0206</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2019-01-04</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001681087</issuerCik>
        <issuerName>AVROBIO, Inc.</issuerName>
        <issuerTradingSymbol>AVRO</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001484870</rptOwnerCik>
            <rptOwnerName>Blackstone Holdings II L.P.</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O THE BLACKSTONE GROUP L.P.</rptOwnerStreet1>
            <rptOwnerStreet2>345 PARK AVENUE</rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10154</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001762202</rptOwnerCik>
            <rptOwnerName>Blackstone Clarus III L.L.C.</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O THE BLACKSTONE GROUP L.P.</rptOwnerStreet1>
            <rptOwnerStreet2>345 PARK AVENUE</rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10154</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001464695</rptOwnerCik>
            <rptOwnerName>Blackstone Holdings I/II GP Inc</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O THE BLACKSTONE GROUP L.P.</rptOwnerStreet1>
            <rptOwnerStreet2>345 PARK AVENUE</rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10154</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001393818</rptOwnerCik>
            <rptOwnerName>Blackstone Group L.P.</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>345 PARK AVENUE</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10154</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001404071</rptOwnerCik>
            <rptOwnerName>Blackstone Group Management L.L.C.</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O THE BLACKSTONE GROUP L.P.</rptOwnerStreet1>
            <rptOwnerStreet2>345 PARK AVENUE</rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10154</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001070844</rptOwnerCik>
            <rptOwnerName>SCHWARZMAN STEPHEN A</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O THE BLACKSTONE GROUP L.P.</rptOwnerStreet1>
            <rptOwnerStreet2>345 PARK AVENUE</rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10154</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>2962325</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See Footnotes</value>
                    <footnoteId id="F1"/>
                    <footnoteId id="F2"/>
                    <footnoteId id="F3"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">These securities are held directly by Clarus Lifesciences III, L.P. (&quot;Clarus III&quot;). Clarus Ventures III GP, L.P. (&quot;Clarus III GP&quot;) is the sole general partner of Clarus III. Blackstone Clarus III L.L.C. is the sole general partner of Clarus GP.  The sole member of Blackstone Clarus III L.L.C. is Blackstone Holdings II L.P.  The sole general partner of Blackstone Holdings II L.P. is Blackstone Holdings I/II GP Inc.  The controlling shareholder of Blackstone Holdings I/II GP Inc. is The Blackstone Group L.P.  The sole general partner of The Blackstone Group L.P. is Blackstone Group Management L.L.C.  Blackstone Group Management L.L.C. is wholly-owned by Blackstone's senior managing directors and controlled by its founder, Stephen A. Schwarzman.</footnote>
        <footnote id="F2">Information with respect to each of the Reporting Persons is given solely by such Reporting Person, and no Reporting Person has responsibility for the accuracy or completeness of information supplied by another Reporting Person.</footnote>
        <footnote id="F3">Each of such Reporting Persons may be deemed to beneficially own the shares beneficially owned by Clarus III, but each disclaims beneficial ownership of such shares, except to the extent of such Reporting Person's pecuniary interest therein. The filing of this statement shall not be deemed to be an admission that, for purposes of Section 16 of the Securities Exchange Act of 1934 or otherwise, the Reporting Persons are the beneficial owners of any securities reported herein.</footnote>
    </footnotes>

    <remarks>This Form 3 is being filed in connection with the acquisition by The Blackstone Group L.P. and certain of its affiliates (&quot;Blackstone&quot;) of Clarus Ventures, LLC and certain of its affiliates (collectively, &quot;Clarus&quot;).  On January 4, 2019, Blackstone integrated the Clarus business into Blackstone (the &quot;Clarus Integration&quot;).  As a result of such integration, Blackstone may be deemed to have become the beneficial owner of the securities beneficially owned by Clarus, including the securities of the Issuer.</remarks>

    <ownerSignature>
        <signatureName>BLACKSTONE CLARUS III L.L.C., By: Blackstone Holdings II L.P., its managing member, By: Blackstone Holdings I/II GP Inc., its general partner, By: /s/ John G. Finley, Name: John G. Finley, Title: Chief Legal Officer</signatureName>
        <signatureDate>2019-01-10</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>BLACKSTONE HOLDINGS II L.P.,  By: Blackstone Holdings I/II GP Inc., its general partner,  By: /s/ John G. Finley, Name:   John G. Finley, Title:   Chief Legal Officer</signatureName>
        <signatureDate>2019-01-10</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>BLACKSTONE HOLDINGS I/II GP INC., By: /s/ John G. Finley, Name:   John G. Finley, Title:   Chief Legal Officer</signatureName>
        <signatureDate>2019-01-10</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>THE BLACKSTONE GROUP L.P., By: Blackstone Group Management L.L.C., its general partner, By: /s/ John G. Finley, Name:   John G. Finley, Title:   Chief Legal Officer</signatureName>
        <signatureDate>2019-01-10</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>BLACKSTONE GROUP MANAGEMENT L.L.C., By: /s/ John G. Finley, Name:   John G. Finley,  Title:   Chief Legal Officer</signatureName>
        <signatureDate>2019-01-10</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>/s/ Stephen A. Schwarzman</signatureName>
        <signatureDate>2019-01-10</signatureDate>
    </ownerSignature>
</ownershipDocument>
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</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
