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Provision for (Benefit from) Income Taxes - Reconciliation of Federal Income Tax Rate (Detail) - USD ($) $ in Millions | 12 Months Ended
--- | ---
Dec. 31, 2025 | Dec. 31, 2024 | Dec. 31, 2023
Income Tax Expense (Benefit), Effective Income Tax Rate Reconciliation, Amount [Abstract] |  |  |
U.S. federal statutory tax rate | $ 475 | $ 365 | $ 212
State and local income tax, net of federal benefit | 51 | 33 | (81)
Other | (2) | 2 | (2)
Global intangible low-taxed income | (22) | (29) | 45
Other | (1) | (6) | (1)
Research and development tax credits | (53) | (64) | (74)
Changes in valuation allowances | (1) | 3 | (930)
Stock-based compensation | (66) | (78) | 25
Officer’s compensation | 32 | 28 | 32
Other | 29 | 13 | 16
Change in unrecognized tax benefits | 11 | 3 | 9
Acquisition-related effects | 29 | (5) | 3
Provision for (benefit from) income taxes | $ 513 | $ 313 | $ (723)
Effective Income Tax Rate Reconciliation, Percent [Abstract] |  |  |
U.S. federal statutory tax rate | 21.00% | 21.00% | 21.00%
State and local income tax, net of federal benefit | 2.30% | 1.90% | (8.10%)
Other | (0.10%) | 0.10% | (0.20%)
Global intangible low-taxed income | (1.00%) | (1.60%) | 4.50%
Other | (0.10%) | (0.30%) | (0.10%)
Research and development tax credits | (2.30%) | (3.70%) | (7.30%)
Changes in valuation allowances | (0.10%) | 0.20% | (92.20%)
Stock-based compensation | (2.90%) | (4.50%) | 2.50%
Officer’s compensation | 1.40% | 1.60% | 3.20%
Acquisition-related effects | 1.30% | (0.30%) | 0.30%
Other | 1.30% | 0.80% | 1.50%
Change in unrecognized tax benefits | 0.50% | 0.20% | 0.90%
Effective Income Tax Rate Reconciliation, Percent | 22.70% | 18.00% | (71.70%)
Ireland |  |  |
Income Tax Expense (Benefit), Effective Income Tax Rate Reconciliation, Amount [Abstract] |  |  |
Statutory tax rate difference | $ (45) | $ (31) | $ (20)
Other | $ (17) | $ 1 | $ 12
Effective Income Tax Rate Reconciliation, Percent [Abstract] |  |  |
Statutory tax rate difference | (2.00%) | (1.80%) | (1.90%)
Other | (0.70%) | 0.00% | 1.20%
Brazil |  |  |
Income Tax Expense (Benefit), Effective Income Tax Rate Reconciliation, Amount [Abstract] |  |  |
Other | $ 0 | $ 2 | $ 10
Withholding | $ 30 | $ 18 | $ 0
Effective Income Tax Rate Reconciliation, Percent [Abstract] |  |  |
Other | 0.00% | 0.10% | 0.90%
Withholding | 1.30% | 1.00% | 0.00%
Foreign Tax Jurisdiction, Other |  |  |
Income Tax Expense (Benefit), Effective Income Tax Rate Reconciliation, Amount [Abstract] |  |  |
Statutory tax rate difference | $ 63 | $ 58 | $ 21
Effective Income Tax Rate Reconciliation, Percent [Abstract] |  |  |
Statutory tax rate difference | 2.80% | 3.30% | 2.10%

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