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Consolidated Statements of Changes in Shareholders’ Equity - USD ($) $ in Thousands | Total | Preferred Stock Series A Convertible Preferred Shares | Preferred Stock Series B Convertible Preferred Shares | Preferred Stock Series C Convertible Preferred Shares | Common Stock | Additional Paid-in Capital | Accumulated Deficit
--- | --- | --- | --- | --- | --- | --- | ---
Shareholders' equity, beginning balance (in shares) at Dec. 31, 2012 |  | 13,025,765 | 7,247,070 | 0 | 36,453,715 |  |
Shareholders' equity, beginning balance at Dec. 31, 2012 | $ 17,969 | $ 5,346 | $ 11,952 | $ 0 | $ 1,840 | $ 747 | $ (1,916)
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |  |  |
Exercise of stock options (in shares) |  |  |  |  | 1,658,197 |  |
Exercise of stock options | 295 |  |  |  | $ 445 | (150) |
Stock-based compensation | 1,472 |  |  |  |  | 1,472 |
Issuance of common stock - business combination (in shares) |  |  |  |  | 96,479 |  |
Issuance of common stock - business combination | 404 |  |  |  | $ 404 |  |
Vesting of restricted shares (in shares) |  |  |  |  | 354,730 |  |
Vesting of restricted shares | 320 |  |  |  | $ 320 |  |
Issuance of stock (in shares) |  |  |  | 6,886,442 |  |  |
Issuance of stock | 69,758 |  |  | $ 69,758 |  |  |
Net loss and comprehensive loss for the year | (4,837) |  |  |  |  |  | (4,837)
Shareholders' equity, ending balance (in shares) at Dec. 31, 2013 |  | 13,025,765 | 7,247,070 | 6,886,442 | 38,563,121 |  |
Shareholders' equity, ending balance at Dec. 31, 2013 | $ 85,381 | $ 5,346 | $ 11,952 | $ 69,758 | $ 3,009 | 2,069 | (6,753)
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |  |  |
Exercise of stock options (in shares) | 305,649 |  |  |  | 305,649 |  |
Exercise of stock options | $ 140 |  |  |  | $ 395 | (255) |
Stock-based compensation | 3,871 |  |  |  |  | 3,871 |
Vesting of restricted shares (in shares) |  |  |  |  | 441,676 |  |
Vesting of restricted shares | 651 |  |  |  | $ 651 |  |
Net loss and comprehensive loss for the year | (22,311) |  |  |  |  |  | (22,311)
Shareholders' equity, ending balance (in shares) at Dec. 31, 2014 |  | 13,025,765 | 7,247,070 | 6,886,442 | 39,310,446 |  |
Shareholders' equity, ending balance at Dec. 31, 2014 | $ 67,732 | $ 5,346 | $ 11,952 | $ 69,758 | $ 4,055 | 5,685 | (29,064)
Increase (Decrease) in Stockholders' Equity [Roll Forward] |  |  |  |  |  |  |
Exercise of stock options (in shares) | 4,665,059 |  |  |  | 4,665,059 |  |
Exercise of stock options | $ 1,604 |  |  |  | $ 3,737 | (2,133) |
Stock-based compensation | 8,167 |  |  |  |  | 8,167 |
Vesting of restricted shares (in shares) |  |  |  |  | 100,076 |  |
Vesting of restricted shares | 353 |  |  |  | $ 353 |  |
Issuance of stock (in shares) |  |  |  |  | 8,855,000 |  |
Issuance of stock | 136,251 |  |  |  | $ 136,251 |  |
Conversion of shares (in shares) |  | (13,025,765) | (7,247,070) | (6,886,442) | 27,159,277 |  |
Conversion of shares | 0 | $ (5,346) | $ (11,952) | $ (69,758) | $ 87,056 |  |
Net loss and comprehensive loss for the year | (18,790) |  |  |  |  |  | (18,790)
Shareholders' equity, ending balance (in shares) at Dec. 31, 2015 |  | 0 | 0 | 0 | 80,089,858 |  |
Shareholders' equity, ending balance at Dec. 31, 2015 | $ 195,317 | $ 0 | $ 0 | $ 0 | $ 231,452 | $ 11,719 | $ (47,854)

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