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Business Segment Information - Schedule of Business Segment Information (Details) - USD ($)
$ in Millions
3 Months Ended
Mar. 28, 2026
Mar. 29, 2025
Dec. 31, 2025
Segment Reporting Information [Line Items]      
Total revenues $ 11,005 $ 10,364  
Selling, general and administrative expenses 2,181 2,078  
Research and development expenses 336 342  
Segment income 1,863 1,716  
Restructuring and other costs (49) (98)  
Amortization of acquisition-related intangible assets (430) (429)  
Interest income 233 203  
Interest expense (354) (303)  
Other income/(expense) (9) 3  
Consolidated income before income taxes 1,734 1,620  
Segment assets 113,281 99,041 $ 110,343
Purchases of property, plant and equipment 376 362  
Depreciation of property, plant and equipment 306 276  
Life Sciences Solutions      
Segment Reporting Information [Line Items]      
Total revenues 2,219 1,954  
Analytical Instruments      
Segment Reporting Information [Line Items]      
Total revenues 1,667 1,677  
Specialty Diagnostics      
Segment Reporting Information [Line Items]      
Total revenues 1,124 1,130  
Laboratory Products and Biopharma Services      
Segment Reporting Information [Line Items]      
Total revenues 5,995 5,603  
Segment Reconciling Items      
Segment Reporting Information [Line Items]      
Total revenues 524 482  
Cost of revenues adjustments (14) (11)  
Selling, general and administrative expenses adjustments (43) (14)  
Restructuring and other costs (49) (98)  
Amortization of acquisition-related intangible assets (430) (429)  
Interest income 233 203  
Interest expense (354) (303)  
Other income/(expense) (9) 3  
Segment assets 98,434 85,272  
Purchases of property, plant and equipment 28 36  
Depreciation of property, plant and equipment 0 0  
Segment Reconciling Items | Life Sciences Solutions      
Segment Reporting Information [Line Items]      
Total revenues 417 387  
Segment Reconciling Items | Analytical Instruments      
Segment Reporting Information [Line Items]      
Total revenues 49 41  
Segment Reconciling Items | Specialty Diagnostics      
Segment Reporting Information [Line Items]      
Total revenues 18 18  
Segment Reconciling Items | Laboratory Products and Biopharma Services      
Segment Reporting Information [Line Items]      
Total revenues 41 37  
Operating Segments      
Segment Reporting Information [Line Items]      
Total revenues 11,529 10,846  
Segment income 2,399 2,269  
Operating Segments | Life Sciences Solutions      
Segment Reporting Information [Line Items]      
Total revenues 2,636 2,341  
Cost of revenues 1,004 855  
Selling, general and administrative expenses 496 468  
Research and development expenses 131 139  
Other segment items 50 45  
Segment income 954 834  
Restructuring and other costs (9)    
Segment assets 3,490 3,018  
Purchases of property, plant and equipment 20 43  
Depreciation of property, plant and equipment 70 59  
Operating Segments | Analytical Instruments      
Segment Reporting Information [Line Items]      
Total revenues 1,716 1,718  
Cost of revenues 876 835  
Selling, general and administrative expenses 313 313  
Research and development expenses 139 137  
Other segment items 34 33  
Segment income 355 399  
Restructuring and other costs (4)    
Segment assets 3,104 2,986  
Purchases of property, plant and equipment 36 44  
Depreciation of property, plant and equipment 26 24  
Operating Segments | Specialty Diagnostics      
Segment Reporting Information [Line Items]      
Total revenues 1,142 1,148  
Cost of revenues 657 679  
Selling, general and administrative expenses 177 171  
Research and development expenses 44 45  
Other segment items (49) (51)  
Segment income 313 304  
Segment assets 1,332 1,298  
Purchases of property, plant and equipment 35 33  
Depreciation of property, plant and equipment 24 22  
Operating Segments | Laboratory Products and Biopharma Services      
Segment Reporting Information [Line Items]      
Total revenues 6,036 5,640  
Cost of revenues 4,757 4,410  
Selling, general and administrative expenses 597 588  
Research and development expenses 15 13  
Other segment items (110) (103)  
Segment income 778 731  
Restructuring and other costs (33)    
Segment assets 6,921 6,467  
Purchases of property, plant and equipment 259 205  
Depreciation of property, plant and equipment 186 172  
Elimination of intersegment revenues      
Segment Reporting Information [Line Items]      
Total revenues $ (524) $ (482)