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Share-Based Compensation - Additional Information (Details)
$ / shares in Units, $ in Millions
12 Months Ended
Dec. 31, 2021
USD ($)
period
$ / shares
shares
Dec. 31, 2020
USD ($)
shares
Dec. 31, 2019
USD ($)
shares
Dec. 31, 2018
Mar. 31, 2021
shares
Apr. 30, 2019
shares
Mar. 31, 2019
shares
Apr. 30, 2017
shares
Mar. 31, 2017
shares
Apr. 30, 2015
shares
Oct. 31, 2009
shares
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                      
Aggregate intrinsic value of options exercised under stock option plans | $ $ 613.0 $ 598.0 $ 512.0                
Cash received from option exercises and employee stock purchase plans | $ 276.0 309.0 273.0                
Employee service share-based compensation, tax benefit from exercise of stock options | $ $ 138.0                    
Number of options vested and expected to vest | shares 11,500,000                    
Weighted average remaining contractual life of shares vested and expected to vest, years 5 years                    
Aggregate intrinsic value of shares vested and expected to vest | $ $ 2,720.0                    
Options vested and expected to vest, weighted-average exercise price per share | $ / shares $ 122.97                    
Restricted Stock Units (RSUs)                      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                      
Expected to vest (in shares) | shares 4,300,000                    
Aggregate intrinsic value | $ $ 1,560.0                    
Vested in period, aggregate fair value | $ 578.0 $ 478.0 $ 433.0                
Total unrecognized compensation expense | $ $ 616.0                    
Weighted average period unrecognized compensation expenses are expected to be recognized, years 2 years 2 months 12 days                    
Restricted Stock Units (RSUs) | Employees                      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                      
Share based vesting period 4 years                    
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Rights, Percentage 25.00%                    
Annual Grant Options                      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                      
Percentage vesting upon six months of service 12.50%                    
Percentage vesting per month after six months of service 2.0833%                    
Annual Grant Options | August Grant                      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                      
Percentage vesting at the end of one month 14.5833%                    
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Rights, Percentage 2.0833%                    
Annual Grant Options | February Grant                      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                      
Percentage vesting upon six months of service 12.50%                    
Percentage vesting per month after six months of service 2.0833%                    
Employee Stock                      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                      
Shares were reserved for future issuance (shares) | shares 2,800,000                    
Employee stock purchase plan, shares issued | shares 500,000 500,000 600,000                
Employee stock purchase plan, value of shares issued | $ $ 75.9 $ 71.2 $ 56.4                
Total unrecognized compensation expense | $ $ 38.0                    
Weighted average period unrecognized compensation expenses are expected to be recognized, years 1 year 6 months                    
Nonvested Stock Option                      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                      
Total unrecognized compensation expense | $ $ 122.0                    
Weighted average period unrecognized compensation expenses are expected to be recognized, years 2 years 3 months 18 days                    
Initial RSU grants | Director                      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                      
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Rights, Percentage   33.3333%                  
New Hire Options                      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                      
Percentage vesting per month after one year 2.0833%                    
Percentage vesting upon one year of service 25.00%                    
2010 Incentive Award Plan                      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                      
Share-based compensation, options, expiration term (in years) 10 years                    
Number of shares of common stock reserved for issuance (shares) | shares         97,350,000 103,350,000          
Shares were reserved for future issuance (shares) | shares 25,500,000                    
2010 Incentive Award Plan | Restricted Stock Units (RSUs)                      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                      
Shares were reserved for future issuance (shares) | shares 11,100,000                    
2010 Incentive Award Plan | Annual Grant Options | August Grant                      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                      
Share based vesting period 3 years 6 months                    
2010 Incentive Award Plan | Annual Grant Options | February Grant                      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                      
Share based vesting period 4 years                    
2009 Employment Commencement Incentive Plan                      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                      
Share-based compensation, options, expiration term (in years) 10 years                    
Number of shares of common stock reserved for issuance (shares) | shares                 10,395,000 13,095,000  
2000 Non-Employee Directors' Stock Option Plan                      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                      
Share-based compensation, options, expiration term (in years) 10 years                    
Number of shares of common stock reserved for issuance (shares) | shares                     1,350,000
2000 Non-Employee Directors' Stock Option Plan | Annual Grant Options                      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                      
Share based vesting period       1 year              
2000 Non-Employee Directors' Stock Option Plan | Initial Grant Options                      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                      
Stock options granted initial vesting period, years       3 years              
Percentage vesting per month after one year   2.7778%                  
Percentage vesting upon one year of service   33.3333%                  
2000 Employee Stock Purchase Plan | Employee Stock                      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                      
Minimum hours employed per week 20 hours                    
Minimum months employed per year 5 months                    
Maximum percentage of employees on stockholders to participate in ESPP 5.00%                    
Percentage of employee payroll deduction under the stock plan, maximum 15.00%                    
Duration for each offering period 24 months                    
Number of shorter purchase periods that each offering period is divided into | period 4                    
Duration of each shorter offering period 6 months                    
Discount on fair market value on the offering date 85.00%                    
Discount on fair market value on the purchase date 85.00%                    
Period of look-back that could cause offering period to reset 2 years                    
Share-based compensation arrangement by share-based payment award, number of shares available for grant | shares             18,270,945 22,770,945