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Consolidated Statements Of Cash Flows - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Operating activities:      
Net income $ 1,728.1 $ 1,066.8 $ 1,381.8
Adjustments to reconcile net income to net cash provided by operating activities:      
Depreciation and loss on disposal of property, plant, and equipment, net 282.8 226.4 160.0
Amortization of intangible assets 27.4 49.8 43.0
Loss (gain) on investments, accretion of discounts, and amortization of premiums on investments, net 10.6 (55.1) (6.0)
Deferred income taxes (62.6) 57.6 (8.0)
Share-based compensation expense 449.2 395.4 335.8
Amortization of contract acquisition assets 22.0 17.1 13.1
Changes in operating assets and liabilities, net of effects of acquisitions:      
Accounts receivable (142.3) 5.7 38.8
Inventory (256.0) (170.1) (360.5)
Prepaids and other assets (204.9) (111.8) (116.9)
Accounts payable 36.0 (32.3) 12.3
Accrued compensation and employee benefits 115.1 (16.6) 57.4
Deferred revenue 32.6 15.0 35.5
Other liabilities 51.4 36.9 11.9
Net cash provided by operating activities 2,089.4 1,484.8 1,598.2
Investing activities:      
Purchase of investments (6,452.0) (4,292.9) (3,346.2)
Proceeds from sales of investments 84.9 800.7 107.3
Proceeds from maturities of investments 4,267.8 2,930.8 2,569.8
Purchase of property, plant, and equipment and intellectual property (353.5) (341.5) (425.6)
Acquisition of businesses, net of cash 8.7 37.7 59.7
Net cash used in investing activities (2,461.5) (940.6) (1,154.4)
Financing activities:      
Proceeds from issuance of common stock relating to employee stock plans 276.5 308.8 272.8
Taxes paid related to net share settlement of equity awards (211.6) (175.2) (159.1)
Repurchase of common stock 0.0 (134.3) (269.5)
Capital contribution from noncontrolling interest 0.0 0.0 10.0
Payment of deferred purchase consideration (21.9) (85.0) (22.6)
Net cash provided by (used in) financing activities 43.0 (85.7) (168.4)
Effect of exchange rate changes on cash, cash equivalents, and restricted cash (3.4) (2.6) (2.2)
Net increase (decrease) in cash, cash equivalents, and restricted cash (332.5) 455.9 273.2
Cash, cash equivalents, and restricted cash, beginning of year 1,638.5 1,182.6 909.4
Cash, cash equivalents, and restricted cash, end of year $ 1,306.0 $ 1,638.5 $ 1,182.6