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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
$ in Millions
3 Months Ended
Mar. 31, 2022
Mar. 31, 2021
Operating activities:    
Net income $ 369.4 $ 435.2
Adjustments to reconcile net income to net cash provided by operating activities:    
Depreciation and loss on disposal of property, plant, and equipment 77.7 64.8
Amortization of intangible assets 6.1 6.9
Gain on sale of business (3.8) 0.0
Loss (gain) on investments, accretion, and amortization, net 26.0 (12.6)
Deferred income taxes (14.4) 44.7
Share-based compensation expense 120.8 103.2
Amortization of contract acquisition assets 6.6 4.9
Changes in operating assets and liabilities, net of effects of acquisitions:    
Accounts receivable (123.4) (14.3)
Inventory (120.1) (41.2)
Prepaids and other assets (21.7) (73.2)
Accounts payable (1.9) 23.7
Accrued compensation and employee benefits (130.3) (40.2)
Deferred revenue 11.4 6.8
Other liabilities 20.6 (31.1)
Net cash provided by operating activities 223.0 477.6
Investing activities:    
Purchase of investments (1,187.3) (1,833.1)
Proceeds from sales of investments 0.0 72.0
Proceeds from maturities of investments 1,067.7 1,231.4
Purchase of property, plant, and equipment and intellectual property (95.1) (58.6)
Acquisition of businesses, net of cash 0.0 (8.7)
Net cash used in investing activities (214.7) (597.0)
Financing activities:    
Proceeds from issuance of common stock relating to employee stock plans 80.0 84.0
Taxes paid related to net share settlement of equity awards (172.2) (178.3)
Repurchase of common stock (106.5) 0.0
Payment of deferred purchase consideration (1.2) (7.9)
Net cash used in financing activities (199.9) (102.2)
Effect of exchange rate changes on cash, cash equivalents, and restricted cash 3.8 0.8
Net increase (decrease) in cash, cash equivalents, and restricted cash (187.8) (220.8)
Cash, cash equivalents, and restricted cash, beginning of period 1,306.0 1,638.5
Cash, cash equivalents, and restricted cash, end of period $ 1,118.2 $ 1,417.7